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anti-Rabbit MCL-1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MCL-1 Antibody (supplied by: Log in to see )

Antigen
Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
  • AW556805
  • bcl2-L-3
  • BCL2L3
  • EAT
  • mcl-1
  • Mcl-1
  • MCL1-ES
  • mcl1/EAT
  • MCL1L
  • MCL1S
  • TM
Reactivity
Cat (Feline), Dog (Canine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
290
101
67
8
7
4
3
3
2
1
1
1
Host
Rabbit
204
76
18
2
Clonality
Polyclonal
Conjugate
This MCL-1 antibody is un-conjugated
11
9
9
6
6
5
3
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
244
118
102
57
55
31
26
22
20
8
7
6
1
Supplier
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Catalog No. ABIN126984
$ 390.50
Plus shipping costs $45.00

Similar anti-MCL-1 Antibodies

Application / Reactivity Human Cat (Feline) Dog (Canine) Monkey Mouse (Murine) Pig (Porcine) Rabbit Rat (Rattus)
Western Blotting (WB) 239 Antibodies 2 Antibodies 8 Antibodies 5 Antibodies 63 Antibodies 7 Antibodies 4 Antibodies 45 Antibodies
Immunoprecipitation (IP) 1 Antibodies 2 Antibodies 21 Antibodies 3 Antibodies 5 Antibodies 2 Antibodies 2 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 58 Antibodies

General

Antigen Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Antibodies
Reactivity Cat (Feline), Dog (Canine), Human, Monkey, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(290), (101), (67), (8), (7), (4), (3), (3), (2), (1), (1), (1)
Host Rabbit
(204), (76), (18), (2)
Clonality
Polyclonal
Conjugate This MCL-1 antibody is un-conjugated
(11), (9), (9), (6), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(244), (118), (102), (57), (55), (31), (26), (22), (20), (8), (7), (6), (1)
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Product Details anti-MCL-1 Antibody

Target Details MCL-1 Application Details Handling Images
Specificity This antibody detects Mcl-1.
Purification Affinity Chromatography.
Immunogen Synthetic peptide corresponding to residues surrounding amino acid 131 of human Mcl-1

Target Details MCL-1

Product Details anti-MCL-1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MCL1 (MCL1 Antibody Abstract)
Background Mcl-1 (Myeloid cell leukemia-1) is a 37 kDa Bcl-2-related protein with an apparent molecular weight of 43 kDa on SDS-PAGE. Mcl-1 was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-β1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
Gene ID 4170
NCBI Accession NP_001184249
UniProt Q07820
Research Area Cancer, Apoptosis/Necrosis
Pathways MAPK Signaling

Application Details

Product Details anti-MCL-1 Antibody Target Details MCL-1 Handling Images back to top
Application Notes Western Blot (0.5-4 μg/mL). Immunoprecipitation (10-20 μg/mL). Immunohistochemistry (10-20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Images back to top
Concentration 0.2 mg/mL
Buffer PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.

Images

Product Details anti-MCL-1 Antibody Target Details MCL-1 Application Details Handling back to top
Supplier Images
 image for anti-MCL-1 antibody (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1) (ABIN126984) anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) antibody