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MAP Kinase Interacting serine/threonine Kinase 1 ELISA Kits (MKNK1)
On www.antibodies-online.com are 6 MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) ELISA Kits from 2 different suppliers available. Additionally we are shipping MKNK1 Antibodies (134) and MKNK1 Proteins (10) and many more products for this protein. A total of 163 MKNK1 products are currently listed.
Synonyms:
2410048M24Rik, Erk-1, Erk1, Ert2, Esrk1, MAPK1, MKNK1, Mnk1, Mtap2k, p44, p44erk1, p44mapk, Prkm3, zgc:171912
list all ELISA KIts Gene Name GeneID UniProt
MKNK1 8569 Q9BUB5
MKNK1 17346 O08605
MKNK1 500526 Q4G050

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MKNK1 (MKNK1) ELISA Kits by Reactivity

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More ELISA Kits for MKNK1 Interaction Partners

Human MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. MNK1 encodes a Ser/Thr protein kinase that interacts with extracellular signal-regulated kinase 1 (show MAPK3 ELISA Kits) and p38 mitogen-activated protein kinase (show MAPK14 ELISA Kits), a pathway that is involved in Blood Pressure regulation through norepinephrine and angiotensin II.

  2. Data show that galeterone (gal (show GAL ELISA Kits)) and VNPT55 inhibit migration and invasion of prostate cancer cells, possibly by down-regulating protein expression via antagonizing the Mnk1/2-eIF4E (show EIF4E ELISA Kits) axis.

  3. data suggest a physiological role for MNK1a-Ser (show SIGLEC1 ELISA Kits)(353) phosphorylation in regulation of the MNK1a kinase, which correlates with increased eIF4E (show EIF4E ELISA Kits) phosphorylation in vitro and in vivo.

  4. Data suggest MNK1/MNK2 (show MKNK2 ELISA Kits) stimulate mRNA translation but only of mRNA containing both 5-prime-terminal cap and hairpin duplex; this stimulation involves up-regulation of phosphorylation/mRNA un-winding activity of eIF4E (show EIF4E ELISA Kits) (via decreased binding to eIF4G (show EIF4G1 ELISA Kits)).

  5. Simultaneous targeting of androgen receptor (show AR ELISA Kits) and MNK1 by novel retinamides inhibits growth of human prostate cancer cell lines.

  6. MNK1 and MNK2 (show MKNK2 ELISA Kits) inhibition ablates eIF4E1 (show EIF4E ELISA Kits) phosphorylation and concurrently enhances eIF4E3 (show EIF4E3 ELISA Kits) expression in diffuse large B-cell lymphoma.

  7. Data show that interferon-gamma (show IFNG ELISA Kits) regulated the metabolism and mRNA translation of macrophages by targeting the kinases mTORC1 and MNK1/2, both of which converge on the selective regulator of translation initiation eukaryotic initiation factor-4E (eIF4E (show EIF4E ELISA Kits)).

  8. Data suggest that a combined pharmacologic inhibition of mTORC1 and Mnk1/2 kinases offers a therapeutic opportunity in blast crisis-chronic myeloid leukemia (BC-CML).

  9. Authors show that MNK (show ATP7A ELISA Kits) regulates SRPK (show SRPK1 ELISA Kits) via mTOR (show FRAP1 ELISA Kits) and AKT (show AKT1 ELISA Kits).

  10. ERK1/2 (show MAPK1/3 ELISA Kits) signal induced MNK (show ATP7A ELISA Kits) catalytic activity enabled enterovirus type 1 internal ribosomal entry site-mediated translation/host cell cytotoxicity through negative regulation of the Ser (show SIGLEC1 ELISA Kits)/Arg (SR)-rich protein kinase (show CDK7 ELISA Kits) (SRPK (show SRPK1 ELISA Kits)).

Mouse (Murine) MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) interaction partners

  1. ERK1 (show MAPK3 ELISA Kits) underexpression is associated with obesity.

  2. retinoschisin (show RS1 ELISA Kits) is a novel regulator of MAP kinase (show MAPK1 ELISA Kits) signalling and exerts an anti-apoptotic effect on retinal cells.

  3. Postnatal chondrocyte-specific deletion of Hdac3 (show HDAC3 ELISA Kits) with an inducible Col2a1 (show COL2A1 ELISA Kits)-Cre caused premature production of pErk1/2 and Mmp13 (show MMP13 ELISA Kits) in the growth plate.

  4. The progress of neurogenesis depended on sustained ERK (show EPHB2 ELISA Kits) phosphorylation and resulted in ERK1/2 (show MAPK1/3 ELISA Kits) translocation to the nucleus.

  5. Mirtazapine suppressed 5-HT (show DDC ELISA Kits)-mediated TGF-beta1 (show TGFB1 ELISA Kits)/Smad3 (show SMAD3 ELISA Kits) and ERK1/2 (show MAPK1/3 ELISA Kits) signaling pathways as well as oxidative stress that contribute to the progression of liver fibrosis.

  6. The kinase TPL2 (show MAP3K8 ELISA Kits) activates ERK (show EPHB2 ELISA Kits) and p38 (show CRK ELISA Kits) signaling to promote neutrophilic inflammation

  7. MNK1 participates in mediating high-fat diet-induced insulin (show INS ELISA Kits) resistance. Our findings reveal distinct roles for the MNKs in a novel area of disease biology

  8. HAS2 (show HAS2 ELISA Kits)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (show MAPK3 ELISA Kits)/EGR1 (show EGR1 ELISA Kits) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (show TGFB1 ELISA Kits)-stimulated CD44V6/ERK (show EPHB2 ELISA Kits)/EGR1 (show EGR1 ELISA Kits) signaling.

  9. We also demonstrated that ERK1 (show MAPK3 ELISA Kits) deletion potentiates DC vaccination and provides a survival advantage in high-grade gliomas.

  10. Low frequency pulsed electromagnetic field (PEMF) induced the activation of extracellular signal-regulated kinases ERK1/2 (show MAPK1/3 ELISA Kits), and the phosphorylation level of ERK1/2 (show MAPK1/3 ELISA Kits) increased after 15 min when exposed to PEMF.

MKNK1 Antigen Profile

Antigen Summary

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with MKNK1

  • MAP kinase interacting serine/threonine kinase 1 (MKNK1) Elisa Kit
  • MAP kinase interacting serine/threonine kinase 1 (mknk1) Elisa Kit
  • MAP kinase-interacting serine/threonine kinase 1 (Mknk1) Elisa Kit
  • mitogen activated protein kinase 3 (Mapk3) Elisa Kit
  • mitogen-activated protein kinase 3 (Mapk3) Elisa Kit
  • 2410048M24Rik Elisa Kit
  • Erk-1 Elisa Kit
  • Erk1 Elisa Kit
  • Ert2 Elisa Kit
  • Esrk1 Elisa Kit
  • MAPK1 Elisa Kit
  • MKNK1 Elisa Kit
  • Mnk1 Elisa Kit
  • Mtap2k Elisa Kit
  • p44 Elisa Kit
  • p44erk1 Elisa Kit
  • p44mapk Elisa Kit
  • Prkm3 Elisa Kit
  • zgc:171912 Elisa Kit

Protein level used designations for MKNK1

MAP kinase interacting serine/threonine kinase 1 , MAP kinase-interacting serine/threonine-protein kinase 1 , MAP kinase signal-integrating kinase 1 , MAPK signal-integrating kinase 1 , mnk1 , MAP kinase 1 , MAP kinase 3 , MAP kinase isoform p44 , MAPK 1 , MAPK 3 , extracellular signal-regulated kinase 1 , insulin-stimulated MAP2 kinase , microtubule-associated protein 2 kinase , mitogen-activated 3 , mitogen-activated protein kinase 1 , mitogen-activated protein kinase 3 , p44 MAP kinase , pp42/MAP kinase

GENE ID SPECIES
469189 Pan troglodytes
555974 Danio rerio
771961 Gallus gallus
8569 Homo sapiens
525647 Bos taurus
17346 Mus musculus
500526 Rattus norvegicus
50689 Rattus norvegicus
26417 Mus musculus
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