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anti-Human RPS6KA1 antibody for Immunofluorescence

Recommended RPS6KA1 Antibody (supplied by: Log in to see )

Antigen
Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) Antibodies
  • Rsk1
  • p90rsk
  • rsk
  • HU-1
  • MAPKAPK1A
  • RSK
  • RSK1
  • RPS6KA
  • hu-1
  • mapkapk1a
  • rsk1
  • CLS
  • HU-3
  • ISPK-1
  • MAPKAPK1B
  • MRX19
  • RSK2
  • S6K-alpha3
  • p90-RSK2
  • pp90RSK2
  • ribosomal protein S6 kinase polypeptide 1
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3
  • Rps6ka1
  • RPS6KA1
  • rps6ka1
  • RPS6KA3
Epitope
AA 1-184
58
44
36
26
26
25
18
12
9
8
8
8
8
8
6
5
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
336
179
149
35
15
9
9
6
6
4
4
2
2
1
1
1
1
Host
Mouse
332
40
Clonality
Monoclonal
Conjugate
This RPS6KA1 antibody is un-conjugated
21
20
18
12
12
12
6
6
5
5
5
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
265
157
96
62
56
47
43
42
19
7
2
1
1
1
Options
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Catalog No. ABIN967837
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.813965 ABIN967838 IF IP IHC WB Mouse IgG2a AA 1-184 Log in to see 78-RSK 5
11.813965 ABIN2856202 ICC IF WB Rabbit IgG Center Log in to see Polyclonal
11.813965 ABIN500636 EIA IF WB Rabbit IgG C-Term Log in to see Polyclonal
11.813965 ABIN1870594 IF IHC WB Rabbit IgG pThr348 Log in to see Polyclonal
11.813965 ABIN2424865 IF IHC WB Rabbit IgG pThr348 Log in to see Polyclonal
11.813965 ABIN256570 ICC IF Rabbit IgG N-Term, pSer372, pThr368 Log in to see Polyclonal
11.813965 ABIN519888 IF ELISA WB Mouse IgG2b kappa AA 1-735, full length Log in to see 4E11
11.813965 ABIN4351277 ELISA ICC IF WB Rabbit C-Term Log in to see Polyclonal
11.813965 ABIN4351278 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN196796 IF IHC (p) WB Rabbit pThr348 Log in to see Polyclonal 3
1 ABIN197328 IF WB Rabbit Thr348 Log in to see Polyclonal 3
1 ABIN361702 ELISA ICC IF IP WB Rabbit C-Term Log in to see Polyclonal 4
1 ABIN302982 IF IHC (p) Rabbit IgG pSer372, pThr368 Log in to see Polyclonal
1 ABIN2486892 ELISA ICC IF IP WB Alkaline Phosphatase (AP) Rabbit C-Term Log in to see Polyclonal 4
1 ABIN2486895 ELISA ICC IF IP WB FITC Rabbit C-Term Log in to see Polyclonal 4
1 ABIN2486896 ELISA ICC IF IP WB HRP Rabbit C-Term Log in to see Polyclonal 4
1 ABIN2486898 ELISA ICC IF IP WB PerCP Rabbit C-Term Log in to see Polyclonal 4
1 ABIN2486885 ELISA ICC IF IP WB Atto 488 Rabbit C-Term Log in to see Polyclonal 4
1 ABIN2486889 ELISA ICC IF IP WB Atto 655 Rabbit C-Term Log in to see Polyclonal 4
1 ABIN2486886 ELISA ICC IF IP WB Atto 565 Rabbit C-Term Log in to see Polyclonal 4

Top referenced anti-RPS6KA1 antibody for Immunofluorescence

Similar anti-RPS6KA1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Chicken
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies 1 Antibodies 1 Antibodies
Western Blotting (WB) 242 Antibodies 128 Antibodies 101 Antibodies 13 Antibodies 9 Antibodies
Immunoprecipitation (IP) 43 Antibodies 32 Antibodies 32 Antibodies 2 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 53 Antibodies 27 Antibodies 28 Antibodies 2 Antibodies
Immunohistochemistry (IHC) 90 Antibodies 23 Antibodies

General

Antigen Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) Antibodies
Epitope AA 1-184
(58), (44), (36), (26), (26), (25), (18), (12), (9), (8), (8), (8), (8), (8), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(336), (179), (149), (35), (15), (9), (9), (6), (6), (4), (4), (2), (2), (1), (1), (1), (1)
Host Mouse
(332), (40)
Clonality (Clone)
Monoclonal   ( )
Conjugate This RPS6KA1 antibody is un-conjugated
(21), (20), (18), (12), (12), (12), (6), (6), (5), (5), (5), (5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(265), (157), (96), (62), (56), (47), (43), (42), (19), (7), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-RPS6KA1 Antibody

Target Details RPS6KA1 Application Details Handling References for anti-RPS6KA1 Antibody (ABIN967837) Images
Cross-Reactivity Dog (Canine), Rat (Rattus), Mouse (Murine), Chicken
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human p90[rsk] aa. 1-184
Clone 78-RSK
Isotype IgG2a

Target Details RPS6KA1

Product Details anti-RPS6KA1 Antibody Application Details Handling References for anti-RPS6KA1 Antibody (ABIN967837) Images back to top
Antigen
Alternative Name Rsk (RPS6KA1 Antibody Abstract)
Background The p90[rsk] (Rsk) and p70[s6k] kinases were first identified based on their ability to phosphorylate the 40S ribosomal protein S6 in vitro. Both of these enzymes are differentially regulated by serine/threonine phosphorylation in response to mitogenic stimulation. ERK1 and ERK2 have been shown to regulate Rsk activity. Once activated by this phosphorylation, a significant amount of Rsk can be found in the nucleus, suggesting that it has a role in nuclear signaling events. The regulation of nuclear Rsk and ERK activities by growth factors is coordinated with the induction of several early response genes. Rsk has also been shown to be activated by ionizing radiation, presumably through an activated MAP kinase. Studies in Xenopus oocytes and mouse NIH/3T3 cells indicate that inactive Rsk and ERK2 exist in a complex of approximately 110kDa. Upon phosphorylation of Rsk and ERK2, the heterodimer dissociates and at least a portion of these activated kinases translocate to the nucleus.
Molecular Weight 90 kDa
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Handling References for anti-RPS6KA1 Antibody (ABIN967837) Images back to top
Comment

Related Products: ABIN967389, ABIN968533

Restrictions For Research Use only

Handling

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Application Details References for anti-RPS6KA1 Antibody (ABIN967837) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.

References for anti-RPS6KA1 Antibody (ABIN967837)

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Application Details Handling Images back to top
Product cited in:

Moor, Gan, Karmazyn, Fliegel: "Activation of Na+/H+ exchanger-directed protein kinases in the ischemic and ischemic-reperfused rat myocardium." in: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 16113-22, 2001

Morrione, Navarro, Romano, Dews, Reiss, Valentinis, Belletti, Baserga: "The role of the insulin receptor substrate-1 in the differentiation of rat hippocampal neuronal cells." in: Oncogene, Vol. 20, Issue 35, pp. 4842-52, 2001

Majka, Janowska-Wieczorek, Ratajczak, Kowalska, Vilaire, Pan, Honczarenko, Marquez, Poncz, Ratajczak: "Stromal-derived factor 1 and thrombopoietin regulate distinct aspects of human megakaryopoiesis." in: Blood, Vol. 96, Issue 13, pp. 4142-51, 2000

Hsiao, Chou, Shih, Ferrell: "Evidence that inactive p42 mitogen-activated protein kinase and inactive Rsk exist as a heterodimer in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 12, pp. 5480-4, 1994

Chung, Pelech, Blenis: "Mitogen-activated Swiss mouse 3T3 RSK kinases I and II are related to pp44mpk from sea star oocytes and participate in the regulation of pp90rsk activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4981-5, 1991

Images

Product Details anti-RPS6KA1 Antibody Target Details RPS6KA1 Application Details Handling References for anti-RPS6KA1 Antibody (ABIN967837) back to top
Supplier Images
Western Blotting (WB) image for anti-RPS6KA1 antibody (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1) (AA 1-184) (ABIN967837) Western blot analysis of Rsk on A431 cell lysate. Lane 1: 1:1000, lane 2: 1:2000, lan...
Immunofluorescence (IF) image for anti-RPS6KA1 antibody (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1) (AA 1-184) (ABIN967837) Immunofluorescent staining of Hs 766T cells.