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RPS6KA1 Products

(Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

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This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured RPS6KA1 Categories

RPS6KA1 Antibodies

High quality antibodies with extensive validation data.

RPS6KA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

RPS6KA1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended RPS6KA1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN7270035
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, ELISA, WB
Validations
  • (4)
Cat. No. ABIN519888
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7180062
Quantity 100 μL
Datasheet Datasheet

Recommended RPS6KA1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959192
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Cell ELISA
Validations
Cat. No. ABIN2748625
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2748547
Quantity 96 tests
Datasheet Datasheet

Recommended RPS6KA1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093388
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133197
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1318819
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our RPS6KA1 products

Lagares-Tena, García-Monclús, López-Alemany, Almacellas-Rabaiget, Huertas-Martínez, Sáinz-Jaspeado, Mateo-Lozano, Rodríguez-Galindo, Rello-Varona, Herrero-Martín, Tirado: "Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway." in: Oncotarget, Vol. 7, Issue 35, pp. 56889-56903, (2016) (PubMed).

Chaturvedi, Poppleton, Stringfield, Barbier, Patel: "Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase." in: Molecular and cellular biology, Vol. 26, Issue 12, pp. 4586-600, (2006) (PubMed).

Wingate, Campbell, Peggie, Arthur: "Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation." in: The Biochemical journal, Vol. 393, Issue Pt 3, pp. 715-24, (2006) (PubMed).

Inoki, Ouyang, Li, Guan: "Signaling by target of rapamycin proteins in cell growth control." in: Microbiology and molecular biology reviews : MMBR, Vol. 69, Issue 1, pp. 79-100, (2005) (PubMed).

Itoh, Ding, Bains, Wang, Takeishi, Jalili, King, Walsh, Yan, Abe: "Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation." in: The Journal of biological chemistry, Vol. 280, Issue 25, pp. 24135-42, (2005) (PubMed).

Roux, Ballif, Anjum, Gygi, Blenis: "Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 37, pp. 13489-94, (2004) (PubMed).

Bohuslav, Chen, Kwon, Mu, Greene: "p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26115-25, (2004) (PubMed).

Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).

Fernando, Wimalasena: "Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt." in: Molecular biology of the cell, Vol. 15, Issue 7, pp. 3266-84, (2004) (PubMed).

Manning: "Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis." in: The Journal of cell biology, Vol. 167, Issue 3, pp. 399-403, (2004) (PubMed).

Synonyms and alternative names related to RPS6KA1

ribosomal protein S6 kinase A1 (RPS6KA1), ribosomal protein S6 kinase polypeptide 1 (Rps6ka1), ribosomal protein S6 kinase A1-like (RPS6KA1L), ribosomal protein S6 kinase A1 (Rps6ka1), ribosomal protein S6 kinase A1 L homeolog (rps6ka1.L), ribosomal protein S6 kinase a, polypeptide 1 (rps6ka1), HU-1, hu-1, MAPKAPK1A, mapkapk1a, p90rsk, RPS6KA, RSK, rsk, RSK1, Rsk1, rsk1, wu:fc56h07, zgc:152654

Protein level used designations for RPS6KA1

  • 90 kDa ribosomal protein S6 kinase 1
  • MAP kinase-activated protein kinase 1a
  • MAPK-activated protein kinase 1a
  • MAPKAP kinase 1a
  • MAPKAPK-1a
  • RSK-1
  • S6K-alpha 1
  • S6K-alpha-1
  • dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1)
  • p90-RSK 1
  • p90RSK1
  • p90S6K
  • ribosomal S6 kinase 1
  • ribosomal protein S6 kinase alpha 1
  • ribosomal protein S6 kinase alpha-1
  • ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1
  • MAP kinase-activated protein kinase 1
  • MAPK-activated protein kinase 1
  • MAPKAP kinase 1
  • MAPKAPK-1
  • S6KII-alpha
  • p90-RSK
  • ribosomal protein S6 kinase 2 alpha
  • ribosomal protein S6 kinase II alpha
  • MAPKAPK1A
  • S6 protein kinase (Rsk-1)
  • pp90RSK1
  • P90-RSK
  • S6 kinase II beta
  • S6KII-beta
  • ribosomal protein S6 kinase 2 beta
  • ribosomal protein S6 kinase II beta
  • ribosomal protein S6 kinase a, polypeptide 1
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