Browse our BHMT2 Proteins (BHMT2)

Full name:
Betaine--Homocysteine S-Methyltransferase 2 Proteins (BHMT2)
On are 6 Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) Proteins from 3 different suppliers available. Additionally we are shipping BHMT2 Antibodies (26) and BHMT2 Kits (3) and many more products for this protein. A total of 44 BHMT2 products are currently listed.
BHMT2, C81077, D13Ucla2, DKFZp469M1332
list all proteins Gene Name GeneID UniProt
BHMT2 23743 Q9H2M3
BHMT2 64918 Q91WS4
Rat BHMT2 BHMT2 365972 Q68FT5

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BHMT2 Proteins (BHMT2) by Origin

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Human Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) interaction partners

  1. A three-way interaction among maternal and fetal variants in BHMT2, GSTP1 (show GSTP1 Proteins) and GPX3 (show GPX3 Proteins) contribute to congenital heart defects

  2. The faster evolutionary rate of BHMT2 overall suggests that selective constraints were reduced relative to BHMT (show BHMT Proteins).

  3. Multiple SNPs in BHMT (show BHMT Proteins) and BHMT2 were identified to be associated with the occurrence of infant obstructive heart defects and interaction effects with maternal use of folic acid supplements.

  4. No significant level of association was found with cleft lip with or without cleft palate and BHMT2 variants.

  5. gene-gene interaction analysis revealed a significant epistatic interaction of BHMT2 (rs673752), PEMT (show PEMT Proteins) (rs12325817), and PCYT1A (show PCYT1A Proteins) (rs712012) with maternal NCL (show CLN5 Proteins)/P susceptibility.

  6. Hyperhomocysteinemia, a risk factor for coronary diseases, can be caused by genetic mutations in BHMT2 metabolism.

  7. Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.

  8. Common genetic variation in BHMT (show BHMT Proteins) and BHMT2 and functionally characterized BHMT (show BHMT Proteins) SNPs.

Mouse (Murine) Betaine--Homocysteine S-Methyltransferase 2 (BHMT2) interaction partners

  1. the mouse liver extracts, containing the BHMT-2 homocysteine methyltransferase candidate for a similar activity, recognizes (S,S)-AdoMet (show MAT1A Proteins) but not (R,S)-AdoMet (show MAT1A Proteins).

  2. Betaine-homocysteine methyltransferase 2 (Bhmt2) was identified as a diet-dependent genetic factor that affected susceptibility to acetaminophen-induced liver toxicity in mice.

BHMT2 Protein Profile

Protein Summary

Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with BHMT2

  • betaine-homocysteine methyltransferase 2 (BHMT2)
  • betaine--homocysteine S-methyltransferase 2 (BHMT2)
  • betaine-homocysteine methyltransferase 2 (Bhmt2)
  • betaine-homocysteine S-methyltransferase 2 (Bhmt2)
  • BHMT2 protein
  • C81077 protein
  • D13Ucla2 protein
  • DKFZp469M1332 protein

Protein level used designations for BHMT2

betaine-homocysteine methyltransferase 2 , Betaine--homocysteine S-methyltransferase 2 , betaine--homocysteine S-methyltransferase 2 , betaine--homocysteine S-methyltransferase 2-like , S-methylmethionine--homocysteine S-methyltransferase BHMT2 , SMM-hcy methyltransferase

471829 Pan troglodytes
488934 Canis lupus familiaris
100174229 Pongo abelii
100413513 Callithrix jacchus
100465913 Ailuropoda melanoleuca
100588253 Nomascus leucogenys
23743 Homo sapiens
64918 Mus musculus
365972 Rattus norvegicus
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