Alpha-tubulin ubiquitous (tubulin-alpha) is the major constituent of microtubules. Tubulin-alpha binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Acetylation of tubulin-alpha at Lys-40 stabilizes microtubules and affects affinity and processivity of microtubule motors. This modification has a role in multiple cellular functions, ranging from cell motility, cell cycle progression or cell differentiation to intracellular trafficking and signaling.
Each vial contains 0.1 mg IgG in 0.1 mL of PBS pH7.4, 2% BSA with 0.09% sodium azide.
Precaution of Use
Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.