anti-Human TUBB3 antibody for Enzyme Immunoassay

Recommended TUBB3 Antibody (supplied by: Log in to see )

Antigen
Tubulin, Beta, 3 (TUBB3) Antibodies
  • tubb3
  • TUBB3
  • TUBB4
  • CDCBM
  • CFEOM3A
  • beta-4
  • 3200002H15Rik
  • M(beta)3
  • M(beta)6
  • AI325297
  • M(beta)4
  • Tubb
  • Tubb4
  • tubulin, beta 3 class III
  • beta-tubulin 3
  • similar to tubulin, beta 3
  • tubulin, beta, 4
  • tubulin, beta 3
  • beta tubulin3
  • tubulin, beta 2C
  • tubulin, beta 4A class IVA
  • tubb3
  • TUBB3
  • tub3
  • TUBB2C
  • Tubb3
  • Tubb4a
Reactivity
Human
248
119
107
23
20
17
15
8
8
6
6
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
Host
Mouse
135
126
20
15
1
Clonality
Monoclonal
Conjugate
This TUBB3 antibody is un-conjugated
24
13
12
5
5
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
249
110
80
69
66
57
52
19
13
13
12
8
8
5
2
2
2
Supplier
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Catalog No. ABIN1109372
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN784019 EIA IF IHC (p) WB Chicken Ig Log in to see Polyclonal
1 ABIN1109374 EIA IHC (fro) IP WB Mouse IgG1 Log in to see 3D9

General

Antigen Tubulin, Beta, 3 (TUBB3) Antibodies
Reactivity Human
(248), (119), (107), (23), (20), (17), (15), (8), (8), (6), (6), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(135), (126), (20), (15), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TUBB3 antibody is un-conjugated
(24), (13), (12), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(249), (110), (80), (69), (66), (57), (52), (19), (13), (13), (12), (8), (8), (5), (2), (2), (2)
Pubmed 3 references available
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Product Details anti-TUBB3 Antibody

Target Details TUBB3 Application Details Handling References for anti-TUBB3 antibody (ABIN1109372) Images
Specificity Recognizes Tubulin, beta 3, also known as TUBB3.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Ascites
Clone 2-00E-009
Isotype IgG1

Target Details TUBB3

Product Details anti-TUBB3 Antibody Application Details Handling References for anti-TUBB3 antibody (ABIN1109372) Images back to top
Antigen
Alternative Name TUBB3 / TUBB4 (TUBB3 Antibody Abstract)
Background Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non exchangeable site on the alpha-chain. Tubulin is a highly conserved protein with a molecular weight of ~50 kD. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. The two main tubulin isoforms, α- and β-tubulin, are usually products of separate genes. The β-tubulin family includes six expressed genes that produce the polypeptide isoforms known as Classes I through VI, each of which have a distinct pattern of expression. Class III β-tubulin is found in neurons and mammalian testis cells and is widely used as a neuronal marker in developmental neurobiology, neoplasia, and stem cell research. Class III β-tubulin expression in neuronal and neuroblastic tumors is differentiation dependent, and its expression in certain non-neuronal neoplasms has been associated with poor prognosis and/or resistance to chemotherapy.Synonyms: Tubulin beta-3 chain, Tubulin beta-4, Tubulin beta-III
Molecular Weight 50 kDa
Gene ID 10381
Pathways Microtubule Dynamics, M Phase

Application Details

Product Details anti-TUBB3 Antibody Target Details TUBB3 Handling References for anti-TUBB3 antibody (ABIN1109372) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-TUBB3 Antibody Target Details TUBB3 Application Details References for anti-TUBB3 antibody (ABIN1109372) Images back to top
Format Liquid

References for anti-TUBB3 antibody (ABIN1109372)

Product Details anti-TUBB3 Antibody Target Details TUBB3 Application Details Handling Images back to top
Background publications

Laggner, Pipp, Budka, Hainfellner, Preusser: "Immunohistochemical detection of class III beta-tubulin in primary brain tumours: variable expression in most tumour types limits utility as a differential diagnostic marker." in: Histopathology, Vol. 50, Issue 7, pp. 949-52, 2007

Katsetos, Dráberová, Smejkalová, Reddy, Bertrand, de Chadarévian, Legido, Nissanov, Baas, Dráber: "Class III beta-tubulin and gamma-tubulin are co-expressed and form complexes in human glioblastoma cells." in: Neurochemical research, Vol. 32, Issue 8, pp. 1387-98, 2007

Vinores, Derevjanik, Mahlow, Hackett, Haller, deJuan, Frankfurter, Campochiaro: "Class III beta-tubulin in human retinal pigment epithelial cells in culture and in epiretinal membranes." in: Experimental eye research, Vol. 60, Issue 4, pp. 385-400, 1995

Images

Product Details anti-TUBB3 Antibody Target Details TUBB3 Application Details Handling References for anti-TUBB3 antibody (ABIN1109372) back to top
Supplier Images
Western Blotting (WB) image for anti-Tubulin, Beta, 3 (TUBB3) antibody (ABIN1109372) anti-Tubulin, Beta, 3 (TUBB3) antibody
Flow Cytometry (FACS) image for anti-Tubulin, Beta, 3 (TUBB3) antibody (ABIN1109372) anti-Tubulin, Beta, 3 (TUBB3) antibody (Image 2)
Immunofluorescence (IF) image for anti-Tubulin, Beta, 3 (TUBB3) antibody (ABIN1109372) anti-Tubulin, Beta, 3 (TUBB3) antibody (Image 3)