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Browse our TUBB3 Proteins (TUBB3)

Full name:
Tubulin, Beta, 3 Proteins (TUBB3)
On www.antibodies-online.com are 19 Tubulin, Beta, 3 (TUBB3) Proteins from 7 different suppliers available. Additionally we are shipping TUBB3 Antibodies (218) and TUBB3 Kits (10) and many more products for this protein. A total of 254 TUBB3 products are currently listed.
Synonyms:
3200002H15Rik, AI325297, beta-4, CDCBM, CFEOM3A, M(beta)3, M(beta)4, M(beta)6, Tubb, TUBB3, Tubb4
list all proteins Gene Name GeneID UniProt
TUBB3 10381 Q13509
TUBB3 246118 Q4QRB4
TUBB3 22152 Q9ERD7

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TUBB3 Proteins (TUBB3) by Origin

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Top referenced TUBB3 Proteins

  1. Human TUBB3 Protein expressed in Escherichia coli (E. coli) - ABIN1098562 : Tischfield, Baris, Wu, Rudolph, Van Maldergem, He, Chan, Andrews, Demer, Robertson, Mackey, Ruddle, Bird, Gottlob, Pieh, Traboulsi, Pomeroy, Hunter, Soul, Newlin, Sabol, Doherty, de Uzcátegui et al.: Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance. ... in Cell 2010 (PubMed)
    Show all 2 references for ABIN1098562

  2. Human TUBB3 Protein expressed in Escherichia coli (E. coli) - ABIN1047796 : Ranganathan, Dexter, Benetatos, Hudes: Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents. in Biochimica et biophysica acta 1998 (PubMed)

More Proteins for TUBB3 Interaction Partners

Human Tubulin, Beta, 3 (TUBB3) interaction partners

  1. TUBB3 mutations cause both Congenital Fibrosis of the Extraocular Muscles type 3 and malformations of cortical development.

  2. The decreased expression of TUBB3 could be a significant marker for predicting unfavourable prognosis in patients with cutaneous malignant melanoma.

  3. High TUBB3 mRNA expression was associated with breast cancer.

  4. mutations proximal to the TUBB3 kinesin-binding site alter polymerization dynamics.

  5. Functional characterization of MC1R-TUBB3 intergenic splice variants of the human melanocortin 1 receptor has been undertaken in response to ultraviolet irradiation.

  6. TUBB3, TOP2A (show TOP2A Proteins), CYP19A1 (show CYP19A1 Proteins) and CYP2D6 (show CYP2D6 Proteins) gene expression, but not protein expression, was associated with patient survival in breast cancer .

  7. In advanced cervical squamous cell cancer, TUBB3 was highly expressed in 20.%% of cases. It had no impact on survival in patients treated with antimicrotubule agents.

  8. Findings suggest that overexpression of Class III beta-tubulin, Sox2 (show SOX2 Proteins), and nuclear Survivin (show BIRC5 Proteins) might be predictive of taxane resistance and poor progression-free survival in patients with stage III ovarian epithelial cancer.

  9. High level of stathmin (show STMN1 Proteins) exhibited poor response to chemotherapy . Similar effects were not observed for b-III-tubulin (show TUBB Proteins).

  10. Results show an overexpression of TUBB3 in breast cancer brain metastases and its expression was significantly associated with distant metastases. These findings suggest a novel role of TUBB3 in regulation of metastases and integrin-Src (show SRC Proteins) signaling.

Mouse (Murine) Tubulin, Beta, 3 (TUBB3) interaction partners

  1. Results suggest that down syndrome cell adhesion molecule (show DSCAM Proteins) collaborates with deleted in colorectal cancer (show DCC Proteins) to regulate microtubule dynamics via direct binding to dynamic TUBB3 in Netrin-1 (show NTN1 Proteins)-induced axon branching.

  2. Differentiation-mediated activation of JunD results in enhanced TUBB4a expression in P19 embryonal carcinoma cells.

  3. determined the alpha-synuclein-binding domain of beta-III tubulin and demonstrated that a short fragment containing this domain can suppress alpha-synuclein accumulation in the primary cultured cells

  4. Study shows the critical and specific role of Tubb3 on the stereotyped morphological changes and polarization processes that are required for initiating radial migration to the cortical plate.

  5. this study reports that TUBB3, the most dynamic beta-tubulin (show TUBB Proteins) isoform in neurons, directly interacts with the netrin receptor DCC (show DCC Proteins), and that netrin-1 (show NTN1 Proteins) induces this interaction in primary neurons.

  6. Access to a running wheel for 48h induced plastic changes in the expression of astrocyte beta-tubulin (show TUBB Proteins) (III). Expression was increased in the cerebellum while much smaller increases were observed in the other motor regions.

  7. interaction between alpha-syn and beta-III tubulin (show TUBB Proteins) plays an important role in neuronal alpha-syn accumulation in an multiple system atrophy mouse model.

  8. Expression of Tubb3, a beta (show SUCLA2 Proteins)-tubulin (show TUBB Proteins) isotype, is regulated by androgens in mouse and rat Sertoli cells.

  9. these findings indicate that TGF-beta (show TGFB1 Proteins) stimulated aberrant expression of class III beta-tubulin via activation of the ERK (show EPHB2 Proteins) signaling pathway.

  10. Endotatin can inhibit the expression of Tubulin-beta (show TUBB Proteins) in retinal neovascularization.

TUBB3 Protein Profile

Protein Summary

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.

Alternative names and synonyms associated with TUBB3

  • tubulin, beta 3 class III (tubb3)
  • beta-tubulin 3 (tubb3)
  • similar to tubulin, beta 3 (TUBB3)
  • tubulin, beta, 4 (TUBB3)
  • tubulin, beta 3 (TUBB3)
  • tubulin, beta 3 class III (TUBB3)
  • beta tubulin3 (tub3)
  • tubulin, beta 2C (TUBB2C)
  • tubulin, beta 3 class III (Tubb3)
  • tubulin, beta 4A class IVA (Tubb4a)
  • 3200002H15Rik protein
  • AI325297 protein
  • beta-4 protein
  • CDCBM protein
  • CFEOM3A protein
  • M(beta)3 protein
  • M(beta)4 protein
  • M(beta)6 protein
  • Tubb protein
  • TUBB3 protein
  • Tubb4 protein

Protein level used designations for Tubulin, Beta, 3 Proteins (TUBB3)

tubulin beta3 , beta-tubulin 3 , tubulin, beta 3 , tubulin beta-3 chain , TubB , beta-3-tubulin , beta3 tubulin , p-tub3(PCR) , p-umc1181 , tub3(PCR) , umc1181 , beta-tubulin class-IV , tubulin, beta, 3 , tubulin, beta, 4 , class III beta-tubulin , tubulin beta-4 chain , tubulin beta-III , neuron-specific class III beta-tubulin , betaIII-tubulin , tubulin beta-4A chain , tubulin, beta 4

GENE ID SPECIES
395045 Xenopus (Silurana) tropicalis
495319 Xenopus laevis
543473 Triticum aestivum
698646 Macaca mulatta
699231 Macaca mulatta
700985 Macaca mulatta
100581245 Nomascus leucogenys
100613658 Pan troglodytes
542416 Zea mays
417255 Gallus gallus
768070 Bos taurus
10381 Homo sapiens
246118 Rattus norvegicus
22152 Mus musculus
608025 Canis lupus familiaris
22153 Mus musculus
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