Browse our TUBB3 Proteins (TUBB3)

Full name:
Tubulin, Beta, 3 Proteins (TUBB3)
On are 19 Tubulin, Beta, 3 (TUBB3) Proteins from 7 different suppliers available. Additionally we are shipping TUBB3 Antibodies (285) and TUBB3 Kits (11) and many more products for this protein. A total of 323 TUBB3 products are currently listed.
3200002H15Rik, AI325297, beta-4, CDCBM, CFEOM3A, M(beta)3, M(beta)4, M(beta)6, Tubb, TUBB3, Tubb4
list all proteins Gene Name GeneID UniProt
TUBB3 10381 Q13509
TUBB3 246118 Q4QRB4
TUBB3 22152 Q9ERD7

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TUBB3 Proteins (TUBB3) by Origin

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Top referenced TUBB3 Proteins

  1. Human TUBB3 Protein expressed in Escherichia coli (E. coli) - ABIN1098562 : Tischfield, Baris, Wu, Rudolph, Van Maldergem, He, Chan, Andrews, Demer, Robertson, Mackey, Ruddle, Bird, Gottlob, Pieh, Traboulsi, Pomeroy, Hunter, Soul, Newlin, Sabol, Doherty, de Uzcátegui et al.: Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance. ... in Cell 2010 (PubMed)
    Show all 2 references for 1098562

  2. Human TUBB3 Protein expressed in HEK-293 Cells - ABIN2734576 : Qu, Dwyer, Shao, Yang, Huang, Liu: Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance. in Journal of cell science 2013 (PubMed)
    Show all 2 references for 2734576

  3. Human TUBB3 Protein expressed in Escherichia coli (E. coli) - ABIN1047796 : Ranganathan, Dexter, Benetatos, Hudes: Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents. in Biochimica et biophysica acta 1998 (PubMed)

More Proteins for TUBB3 Interaction Partners

Human Tubulin, Beta, 3 (TUBB3) interaction partners

  1. TUBB3 overexpression is linked to an aggressive subtype of urinary bladder cancers, which is characterized by increased genetic instability, p53 (show TP53 Proteins) alterations, and rapid cell proliferation.

  2. The central findings of our study are that TSA (show PRDX2 Proteins) and VPA affect the expression of neuronal lineage genes in an rMSCs culture. After exposure to TSA (show PRDX2 Proteins) or VPA, the expression of early neuronal gene decreases but equally the expression of mature neuron genes increases

  3. a positive correlation was observed between Snail (show SNAI1 Proteins) presence and TUBB3 upregulation in tested adenocarcinoma cell lines.

  4. This elucidates a hitherto unknown role for this microtubule protein and provides insight into correlations between high betaIII-tubulin expression and poor patient outcome in this disease

  5. TUBB3 involvement in breast cancer cells apoptosis

  6. The expressions of TYMS (show TYMS Proteins), TUBB3 and STMN1 (show STMN1 Proteins) were significantly associated with the clinicopathological characteristics of age, gender and family history of gastric cancer, but not with differentiation, growth patterns, metastasis and TNM (show ODZ1 Proteins) staging in patients with gastric cancer.

  7. It findings reveal that expression of relatively low levels of TUBB3 in mitotic cells can be detrimental for their cytokinesis and underscore the importance of CIT-K (show CIT Proteins) in counteracting this event.

  8. Epitaxial growth of alpha1A/betaIII microtubules from heterogeneous brain seeds is inefficient but can be fully rescued by incorporating as little as 5% of brain tubulin into the homogeneous alpha1A/betaIII lattice.

  9. TUBB3 mutations cause both Congenital Fibrosis of the Extraocular Muscles type 3 and malformations of cortical development.

  10. The decreased expression of TUBB3 could be a significant marker for predicting unfavourable prognosis in patients with cutaneous malignant melanoma.

Mouse (Murine) Tubulin, Beta, 3 (TUBB3) interaction partners

  1. Here, we report that dissociation of UNC5C (show Unc5c Proteins) and polymerized TUBB3, the highly dynamic beta-tubulin (show TUBB Proteins) isoform in neurons, is essential for netrin-1 (show NTN1 Proteins)/UNC5C (show Unc5c Proteins)-promoted axon repulsion. These results not only provide a working model of direct modulation of MTs (show NEU2 Proteins) by guidance cues in growth cone navigation but also help us to understand molecular mechanisms underlying developmental brain disorders associated with TUBB3 mutations.

  2. Tubb3 could be regulated by both Akt (show AKT1 Proteins) and Erk (show EPHB2 Proteins) pathways.

  3. It findings reveal that expression of relatively low levels of TUBB3 in mitotic cells can be detrimental for their cytokinesis and underscore the importance of CIT-K (show CIT Proteins) in counteracting this event.

  4. Results suggest that down syndrome cell adhesion molecule (show DSCAM Proteins) collaborates with deleted in colorectal cancer (show DCC Proteins) to regulate microtubule dynamics via direct binding to dynamic TUBB3 in Netrin-1 (show NTN1 Proteins)-induced axon branching.

  5. Differentiation-mediated activation of JunD results in enhanced TUBB4a expression in P19 embryonal carcinoma cells.

  6. determined the alpha-synuclein-binding domain of beta-III tubulin and demonstrated that a short fragment containing this domain can suppress alpha-synuclein accumulation in the primary cultured cells

  7. Study shows the critical and specific role of Tubb3 on the stereotyped morphological changes and polarization processes that are required for initiating radial migration to the cortical plate.

  8. this study reports that TUBB3, the most dynamic beta-tubulin (show TUBB Proteins) isoform in neurons, directly interacts with the netrin receptor DCC (show DCC Proteins), and that netrin-1 (show NTN1 Proteins) induces this interaction in primary neurons.

  9. Access to a running wheel for 48h induced plastic changes in the expression of astrocyte beta-tubulin (show TUBB Proteins) (III). Expression was increased in the cerebellum while much smaller increases were observed in the other motor regions.

  10. interaction between alpha-syn and beta-III tubulin (show TUBB Proteins) plays an important role in neuronal alpha-syn accumulation in an multiple system atrophy mouse model.

TUBB3 Protein Profile

Protein Summary

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.

Alternative names and synonyms associated with TUBB3

  • tubulin, beta 3 class III (tubb3)
  • beta-tubulin 3 (tubb3)
  • similar to tubulin, beta 3 (TUBB3)
  • tubulin, beta, 4 (TUBB3)
  • tubulin, beta 3 (TUBB3)
  • tubulin, beta 3 class III (TUBB3)
  • beta tubulin3 (tub3)
  • tubulin, beta 2C (TUBB2C)
  • tubulin, beta 3 class III (Tubb3)
  • tubulin, beta 4A class IVA (Tubb4a)
  • 3200002H15Rik protein
  • AI325297 protein
  • beta-4 protein
  • CDCBM protein
  • CFEOM3A protein
  • M(beta)3 protein
  • M(beta)4 protein
  • M(beta)6 protein
  • Tubb protein
  • TUBB3 protein
  • Tubb4 protein

Protein level used designations for Tubulin, Beta, 3 Proteins (TUBB3)

tubulin beta3 , beta-tubulin 3 , tubulin, beta 3 , tubulin beta-3 chain , TubB , beta-3-tubulin , beta3 tubulin , p-tub3(PCR) , p-umc1181 , tub3(PCR) , umc1181 , beta-tubulin class-IV , tubulin, beta, 3 , tubulin, beta, 4 , class III beta-tubulin , tubulin beta-4 chain , tubulin beta-III , neuron-specific class III beta-tubulin , betaIII-tubulin , tubulin beta-4A chain , tubulin, beta 4

395045 Xenopus (Silurana) tropicalis
495319 Xenopus laevis
543473 Triticum aestivum
698646 Macaca mulatta
699231 Macaca mulatta
700985 Macaca mulatta
100581245 Nomascus leucogenys
100613658 Pan troglodytes
542416 Zea mays
417255 Gallus gallus
768070 Bos taurus
10381 Homo sapiens
246118 Rattus norvegicus
22152 Mus musculus
608025 Canis lupus familiaris
22153 Mus musculus
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