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Propionyl CoA Carboxylase beta Polypeptide ELISA Kits (PCCB)
On www.antibodies-online.com are 10 Propionyl CoA Carboxylase beta Polypeptide (PCCB) ELISA Kits from 4 different suppliers available. Additionally we are shipping Propionyl CoA Carboxylase beta Polypeptide Antibodies (36) and Propionyl CoA Carboxylase beta Polypeptide Proteins (5) and many more products for this protein. A total of 56 Propionyl CoA Carboxylase beta Polypeptide products are currently listed.
Synonyms:
1300012P06Rik, AI314687, R74805
list all ELISA KIts Gene Name GeneID UniProt
PCCB 5096 P05166
PCCB 24624  
PCCB 66904 Q99MN9

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Human Propionyl CoA Carboxylase beta Polypeptide (PCCB) interaction partners

  1. we identified seven novel genetic variants: p.Leu549Pro, p.Glu564*, p.Leu641Pro in MUT (show MUT ELISA Kits), p.Tyr206Cys in PCCB, p.His194Arg, p.Val298Met in BCKDHA (show BCKDHA ELISA Kits) and p.Glu286_Met290del in BCKDHB (show BCKDHB ELISA Kits) gene. In silico and/or eukaryotic expression studies confirmed pathogenic effect of all novel genetic variants

  2. The majority of patients had mutations in the PCCA (show PCCA ELISA Kits) gene (18/25). A total of 26 mutations were noted: 20 in the PCCA (show PCCA ELISA Kits) gene and 6 in PCCB gene. Seventeen mutations were novel (14 in PCCA (show PCCA ELISA Kits) and 3 in PCCB).

  3. Ten propionic acidemia mutations were confirmed, including 8 affecting the PCCA (show PCCA ELISA Kits) gene and 2 affecting the PCCB gene

  4. The c.-4156_183+3713del mutation is the first known large deletion that affects the PCCB gene functions.

  5. mutations affect homomeric and heteromeric assembly of Propionyl-CoA Carboxylase

  6. Structure-function analysis of a range of isolated PCCB subunit mutants has elucidated the complex relationship between genotype and phenotype in propionic acidemia.

  7. Work showed 15 novel PCCB gene mutations and phenotype-genotype correlations for the prediction of the metabolic outcome and for the implementation of treatments tailored to each PA patient.

  8. pathogenicity of R67S, R165Q and G112D mutations in PCCB gene in propionic acidemia

  9. analysis of PCCA (show PCCA ELISA Kits) and PCCB mutations in propionic acidemia

Propionyl CoA Carboxylase beta Polypeptide (PCCB) Antigen Profile

Antigen Summary

The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Propionyl CoA Carboxylase beta Polypeptide (PCCB)

  • propionyl CoA carboxylase, beta polypeptide (PCCB) Elisa Kit
  • propionyl CoA carboxylase, beta polypeptide (Pccb) Elisa Kit
  • propionyl Coenzyme A carboxylase, beta polypeptide (Pccb) Elisa Kit
  • 1300012P06Rik Elisa Kit
  • AI314687 Elisa Kit
  • R74805 Elisa Kit

Protein level used designations for PCCB

PCCase subunit beta , propanoyl-CoA:carbon dioxide ligase subunit beta , propionyl Coenzyme A carboxylase, beta polypeptide , propionyl-CoA carboxylase beta chain, mitochondrial , propionyl coenzyme A carboxylase, beta polypeptide , PCCase beta subunit , propanoyl-CoA:carbon dioxide ligase beta subunit

GENE ID SPECIES
5096 Homo sapiens
24624 Rattus norvegicus
515902 Bos taurus
100158147 Sus scrofa
66904 Mus musculus
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