Browse our anti-MYL2 (MYL2) Antibodies

Full name:
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow Antibodies (MYL2)
On www.antibodies-online.com are 106 Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) Antibodies from 22 different suppliers available. Additionally we are shipping MYL2 Proteins (16) and MYL2 Kits (5) and many more products for this protein. A total of 132 MYL2 products are currently listed.
Synonyms:
2410014J02Rik, CMH10, Mlc-2, MLC-2v, MLC2, Mlc2v, Mylpc, myosin, regulatory

Most Popular Reactivities for anti-MYL2 (MYL2) Antibodies

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anti-Mouse (Murine) MYL2 Antibodies:

anti-Human MYL2 Antibodies:

anti-Rat (Rattus) MYL2 Antibodies:

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Top referenced anti-MYL2 Antibodies

  1. Human Polyclonal MYL2 Primary Antibody for IHC - ABIN362086 : Janiak, Zemskov, Belkin: Cell surface transglutaminase promotes RhoA activation via integrin clustering and suppression of the Src-p190RhoGAP signaling pathway. in Molecular biology of the cell 2006 (PubMed)
    Show all 3 references for 362086

  2. Human Polyclonal MYL2 Primary Antibody for IF, WB - ABIN197362 : Rameh, Armelin: Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cells. in Molecular and cellular biology 1992 (PubMed)
    Show all 3 references for 197362

  3. Human Polyclonal MYL2 Primary Antibody for IHC (p), WB - ABIN319223 : Li, Wang, Jiao, Lu, Fu, Quong, Dye, Yang, Dai, Ju, Zhang, Li, Burbelo, Stanley, Pestell: Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1 and ROCK signaling. in Molecular and cellular biology 2006 (PubMed)
    Show all 3 references for 319223

  4. Human Monoclonal MYL2 Primary Antibody for ELISA, FACS - ABIN450002 : Samwer, Dehne, Spira, Kollmar, Gerlich, Urlaub, Görlich: The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. in The EMBO journal 2013 (PubMed)
    Show all 3 references for 450002

  5. Human Monoclonal MYL2 Primary Antibody for ELISA, WB - ABIN969302 : Sachdev, Raychowdhury, Sarkar: Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships. in DNA sequence : the journal of DNA sequencing and mapping 2004 (PubMed)
    Show all 2 references for 969302

  6. Human Polyclonal MYL2 Primary Antibody for IHC, IHC (p) - ABIN4337526 : He, Tian, Zhang, Hu, Huang, Zhang, Wang, Zhou: BAF200 is required for heart morphogenesis and coronary artery development. in PLoS ONE 2014 (PubMed)

  7. Human Monoclonal MYL2 Primary Antibody for IF, IP - ABIN561897 : Gannon, Doran, Kirwan, Ohlendieck: Drastic increase of myosin light chain MLC-2 in senescent skeletal muscle indicates fast-to-slow fibre transition in sarcopenia of old age. in European journal of cell biology 2009 (PubMed)

More Antibodies against MYL2 Interaction Partners

Mouse (Murine) Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. transgenic mouse models of hypertrophic cardiomyopathy may be caused by mutations in myosin regulatory light chain

  2. MLC2 phosphorylation regulates actin-based cytokinesis in mouse oocytes, and this regulation may be mediated via a RhoA-MLC2-actin pathway.

  3. Treatment of mice with an AT1R (show AGTRAP Antibodies) biased ligand, acting via beta-arrestin signalling, is able to induce an increase in cardiac contractility associated with an increase in ventricular myosin light chain-2 (show MYL12B Antibodies) phosphorylation

  4. Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice.

  5. Mammalian target of rapamycin (mTOR (show FRAP1 Antibodies)) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein (show TNNT2 Antibodies) expression.

  6. Data indicate that NRG-1beta up-regulated the gene expressions of Nkx2.5 (show NKX2-5 Antibodies), GATA4 (show GATA4 Antibodies), alpha-actin (show ACTA2 Antibodies), MLC-2v, and ANF (show HESX1 Antibodies) in a time-dependent regulation of ErbB (show EGFR Antibodies)/ERK1/2 (show MAPK1/3 Antibodies) pathways.

  7. Results indicated that sine oculis homeobox (show PRRX1 Antibodies) 1 (Six1 (show SIX1 Antibodies)) overexpression could significantly promote the expression of fast-type muscle genes Atp2a1 (show ATP2A1 Antibodies), Srl (show SRL Antibodies), and Mylpf (show MYLPF Antibodies).

  8. High resolution characterization of myosin IIC protein tailpiece and its effect on filament assembly

  9. Accelerated cMLCK protein turnover by the ubiquitin-proteasome system underlies the transition from compensated hypertrophy to decompensated heart failure as a result of reduced phosphorylation of MLC2v.

  10. Results show that the binding force between selenium and cardiac myosin (CM), which consists of two heavy chains (MHC) and two pairs of light chains: MLC1 and MLC2, was 100 times stronger than that of daunorubicin (DNR) and CM.

Human Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) interaction partners

  1. This exome-wide association study indicated that C12orf51 rs11066280, MYL2 rs12229654, and ALDH2 (show ALDH2 Antibodies) rs671 polymorphisms are linked to blood Pb levels in the Korean population.

  2. differential regulation of PKA and cell stiffness in unconfined versus confined cells is abrogated by dual, but not individual, inhibition of Piezo1 and myosin II.

  3. Mutation in myosin regulatory light chain gene is associated with defective myosin motor function that ultimately result in pathological hypertrophic remodeling.

  4. Lipolysis-stimulated lipoprotein receptors (LSRs) localized to bicellular junctions in association with myosin regulatory light chain 2 (MRLC2 (show MYL12B Antibodies)) at low cell densities and to tricellular contacts when myosin phosphatase target subunit 1 (MYPT1 (show PPP1R12A Antibodies)) localized to the bicellular regions.

  5. Structural dynamics-based approach reveals that the E56G mutation in human ventricular essential light chain affects the structure of the actin-myosin complex in the presence of ATP. The mutation increases the population in the S structural state (increasing the duty ratio), and changes the structure of the W state, so that it more closely resembles the S state.

  6. Two siblings with hypertrophic cardiomyopathy had the pathogenic variant p.Ala13Thr variant in MYL2.

  7. the MYL2 gene on chromosome 12 is associated with serum HDL (show HSD11B1 Antibodies)-C levels in Korean men. The association was much stronger in male obese subjects and smokers than that in leaner (show CACNA1A Antibodies) nonsmoking male subjects.

  8. FLNb (show FLNB Antibodies) enhances invasion of cancer cells through phosphorylation of MRLC and FAK (show PTK2 Antibodies).

  9. Ostf1b could constitutively activate the Rho kinase (show ROCK1 Antibodies) 1 (ROCK1 (show ROCK1 Antibodies)) and myosin light chain 2 (MLC2 (show MYL12B Antibodies)) signalling pathway that promotes cell migration, epithelial mesenchymal transition (EMT (show ITK Antibodies)) and cytoskeletal dynamics through stress fibre formation.

  10. Myosin regulatory light chain phosphorylation enhances cardiac beta-myosin in vitro motility under load.

MYL2 Antigen Profile

Antigen Summary

Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Alternative names and synonyms associated with MYL2

  • myosin light chain, phosphorylatable, fast skeletal muscle (Mylpf) antibody
  • Myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like (LOC100353304) antibody
  • myosin, light chain 2, regulatory, cardiac, slow (MYL2) antibody
  • myosin, light chain 2, regulatory, cardiac, slow (Myl2) antibody
  • myosin, light chain 9, regulatory (MYL9) antibody
  • myosin, light polypeptide 2, regulatory, cardiac, slow (Myl2) antibody
  • 2410014J02Rik antibody
  • CMH10 antibody
  • Mlc-2 antibody
  • MLC-2v antibody
  • MLC2 antibody
  • Mlc2v antibody
  • Mylpc antibody
  • myosin antibody
  • regulatory antibody

Protein level used designations for MYL2

MLC2F , fast skeletal myosin light chain 2 , myosin light chain 2 , myosin regulatory light chain 2, skeletal muscle isoform , MLC-2 , MLC-2v , RLC of myosin , cardiac ventricular myosin light chain 2 , myosin regulatory light chain 2, ventricular/cardiac muscle isoform , myosin, light polypeptide 2, regulatory, cardiac, slow , regulatory light chain of myosin , slow cardiac myosin regulatory light chain 2 , cardiac myosin light chain-2 , DTNB , G1 , isoform L20-A , light polypeptide 9 , myosin regulatory light chain 2, smooth muscle major isoform , myosin regulatory light polypeptide 9 , myosin, light polypeptide 9, regulatory , smooth muscle major isoform , myosin light chain 2v , myosin light chain, phosphorylatable, cardiac ventricles , ventricular myosin regulatory light chain

GENE ID SPECIES
17907 Mus musculus
100353304 Oryctolagus cuniculus
4633 Homo sapiens
363925 Rattus norvegicus
505519 Bos taurus
396215 Gallus gallus
17906 Mus musculus
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