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Browse our rho Guanine Nucleotide Exchange Factor (GEF) 3 Proteins (ARHGEF3)

Full name:
rho Guanine Nucleotide Exchange Factor (GEF) 3 Proteins (ARHGEF3)
On www.antibodies-online.com are 4 rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) Proteins from 2 different suppliers available. Additionally we are shipping rho Guanine Nucleotide Exchange Factor (GEF) 3 Antibodies (43) and rho Guanine Nucleotide Exchange Factor (GEF) 3 Kits (2) and many more products for this protein. A total of 54 rho Guanine Nucleotide Exchange Factor (GEF) 3 products are currently listed.
Synonyms:
1200004I24Rik, 9830169H03Rik, ARHGEF3, C76747, DKFZp459N027, GEF3, MGC82822, MGC108040, si:ch211-258l4.8, STA3, Xpln
list all proteins Gene Name GeneID UniProt
ARHGEF3 50650 Q9NR81
ARHGEF3 71704 Q91X46
Rat ARHGEF3 ARHGEF3 290541  

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rho Guanine Nucleotide Exchange Factor (GEF) 3 Proteins (ARHGEF3) by Origin

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More Proteins for rho Guanine Nucleotide Exchange Factor (GEF) 3 Interaction Partners

Zebrafish rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) interaction partners

  1. Evidence for ARHGEF3 being a regulator of transferrin (show Tf Proteins) uptake in erythroid cells, through activation of RHOA (show RHOA Proteins).

Human rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) interaction partners

  1. ARHGEF3 has a crucial role in myeloid differentiation.

  2. ARHGEF3 and RHOA (show RHOA Proteins) are potential regulators of a number of genes in bone cells, with influences on ACTA2 (show ACTA2 Proteins) evident in both osteoblast-like and osteoclast-like cells.

  3. XPLN is an endogenous inhibitor of mTORC2 (show CRTC2 Proteins).

  4. the association between rs7646054 in ARHGEF3 and bone mineral density observed in Caucasians was not replicated in the chinese samples.

  5. a guanine nucleotide exchange factor (show RASGRF1 Proteins) for RhoA (show RHOA Proteins) and RhoB, but not RhoC (show RHOC Proteins)

  6. genetic variation in ARHGEF3 plays a role in the determination of bone density in Caucasian women. This data implicates the RhoGTPase-RhoGEF (show ARHGEF11 Proteins) pathway in osteoporosis.

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) interaction partners

  1. the crystal structure of the tandemly arranged DH-PH domains of mouse Xpln, with a single molecule in the asymmetric unit, was determined at 1.79 A resolution (Xpln)

rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3) Protein Profile

Protein Summary

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3)

  • Rho guanine nucleotide exchange factor (GEF) 3 (arhgef3)
  • Rho guanine nucleotide exchange factor (GEF) 3 (ARHGEF3)
  • Rho guanine nucleotide exchange factor (GEF) 3 (Arhgef3)
  • 1200004I24Rik protein
  • 9830169H03Rik protein
  • ARHGEF3 protein
  • C76747 protein
  • DKFZp459N027 protein
  • GEF3 protein
  • MGC82822 protein
  • MGC108040 protein
  • si:ch211-258l4.8 protein
  • STA3 protein
  • Xpln protein

Protein level used designations for ARHGEF3

Rho guanine nucleotide exchange factor (GEF) 3 , Rho guanine nucleotide exchange factor 3 , rho guanine nucleotide exchange factor 3 , rho guanine nucleotide exchange factor 3-like , 59.8 kDA protein , RhoGEF protein , exchange factor found in platelets and leukemic and neuronal tissues, XPLN

GENE ID SPECIES
444354 Xenopus laevis
460466 Pan troglodytes
476579 Canis lupus familiaris
570228 Danio rerio
613095 Xenopus (Silurana) tropicalis
704764 Macaca mulatta
782247 Bos taurus
100173549 Pongo abelii
100352585 Oryctolagus cuniculus
100387904 Callithrix jacchus
100478961 Ailuropoda melanoleuca
100597599 Nomascus leucogenys
100627663 Sus scrofa
50650 Homo sapiens
71704 Mus musculus
290541 Rattus norvegicus
416000 Gallus gallus
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