Browse our anti-DDIT4 (DDIT4) Antibodies

On www.antibodies-online.com are 89 DNA-Damage-Inducible Transcript 4 (DDIT4) Antibodies from 17 different suppliers available. Additionally we are shipping DDIT4 Proteins (13) and DDIT4 Kits (1) and many more products for this protein. A total of 113 DDIT4 products are currently listed.
Synonyms:
5830413E08Rik, AA415483, dig2, REDD-1, REDD1, rtp801, sb:cb821, zgc:64114
list all antibodies Gene Name GeneID UniProt
DDIT4 54541 Q9NX09
DDIT4 74747 Q9D3F7
DDIT4 140942 Q8VHZ9

Most Popular Reactivities for anti-DDIT4 (DDIT4) Antibodies

anti-Human DDIT4 Antibodies:

anti-Mouse (Murine) DDIT4 Antibodies:

anti-Rat (Rattus) DDIT4 Antibodies:

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More Antibodies against DDIT4 Interaction Partners

Human DNA-Damage-Inducible Transcript 4 (DDIT4) interaction partners

  1. Expression of key autophagy markers (microtubule-associated protein 1A/1B light chain 3 and autophagy protein 5) was markedly reduced in cultured human chondrocytes with REDD1 depletion.

  2. The production of superoxide anion in nockout-Rtp801 mouse lung fibroblasts (MLF) was lower than that in Rtp801 Wt cells after cigarette smoke extract treatment, and it was inhibited in Wt MLF by silencing nicotinamide adenine dinucleotide phosphate oxidase (show DUOX2 Antibodies)-4 (Nox4 (show NOX4 Antibodies)) expression with small interfering Nox4 (show NOX4 Antibodies) RNA.

  3. Changes in REDD1 mRNA and protein have been observed in skeletal muscle under various physiological conditions (e.g., nutrient consumption and resistance exercise) and pathological conditions (e.g., sepsis, alcoholism, diabetes, obesity) suggesting a role for REDD1 in regulating mTORC1-dependent skeletal muscle protein metabolism. [Review]

  4. a novel STAT3 (show STAT3 Antibodies)-dependent mechanism of both IL-6 (show IL6 Antibodies)-induced activation of mTOR (show FRAP1 Antibodies) and IL-6 (show IL6 Antibodies)-dependent reversion of stress-induced inhibition of mTOR (show FRAP1 Antibodies) activity, is reported.

  5. findings implicate REDD1 as a crucial regulator of mTORC1 activity in iron-depleted cells

  6. C/EBPbeta (show CEBPB Antibodies) promotes autophagy in PC3 (show PCSK1 Antibodies) cells by augmenting REDD1 expression.

  7. These data highlight the central role of REDD1 in regulating both protein synthesis and autophagy in skeletal muscle during sepsis.

  8. Findings from this study propose a REDD1-regulated mechanism in T2D skeletal muscle that may contribute to whole body insulin (show INS Antibodies) resistance and may be a target to improve insulin (show INS Antibodies) action in insulin (show INS Antibodies)-resistant individuals.

  9. REDD1 knockout (KO) mice, all skin compartments, epidermal stem, and progenitor cells were protected from atrophic effects of glucocorticoids.

  10. MiR (show MLXIP Antibodies)-630 reduced apoptosis by downregulating several apoptotic modulators, PARP3 (show PARP3 Antibodies), DDIT4, and EP300 (show EP300 Antibodies).

Mouse (Murine) DNA-Damage-Inducible Transcript 4 (DDIT4) interaction partners

  1. Findings suggest that REDD1 is a key mediator of cartilage homeostasis through regulation of autophagy and mitochondrial biogenesis and that REDD1 deficiency exacerbates the severity of injury-induced osteoarthritis.

  2. These data suggest that loss of REDD1 augments the rate of the OV-induced increase in muscle mass by altering multiple protein balance pathways.

  3. The production of superoxide anion in nockout-Rtp801 mouse lung fibroblasts (MLF) was lower than that in Rtp801 Wt cells after cigarette smoke extract treatment, and it was inhibited in Wt MLF by silencing nicotinamide adenine dinucleotide phosphate oxidase (show DUOX1 Antibodies)-4 (Nox4 (show NOX4 Antibodies)) expression with small interfering Nox4 (show NOX4 Antibodies) RNA.

  4. REDD1 is required for normal insulin (show INS Antibodies)-stimulated signaling, and a subtle balance exists between MEK1 (show MAP2K1 Antibodies)/2, REDD1, and mTOR (show FRAP1 Antibodies)

  5. study suggests that VDR (show CYP27B1 Antibodies) regulates Ddit4 expression during epidermal homeostasis and the wound healing process, while elevated Ddit4 represents an early growth-arresting stress response within VDR (show CYP27B1 Antibodies)(-/-) follicles.

  6. REDD1 knockout T cells exhibit a defect in proliferation and cell survival, although markers of activation appear normal. These findings demonstrate a previously unappreciated role for REDD1 in T cell function.

  7. Reactive oxygen species regulation through REDD1/TXNIP (show TXNIP Antibodies) is physiological rheostat controlling stress-induced autophagy.

  8. LPS (show TLR4 Antibodies) induces REDD1 expression by two distinct CREB (show CREB1 Antibodies)-mediated mechanisms

  9. Glucocorticoids induce skin atrophy and activate REDD1 expression.

  10. REDD1 expression limits the nutrient-induced stimulation of protein synthesis and activation of mTORC1 signaling during periods of feed deprivation.

Zebrafish DNA-Damage-Inducible Transcript 4 (DDIT4) interaction partners

  1. Redd1 alters dorsoventral patterning by antagonizing the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.

DDIT4 Antigen Profile

Antigen Summary

HIF-1-responsive gene that may protect some types of cells from hypoxia and H(2)O(2)-triggered apoptosis

Alternative names and synonyms associated with DDIT4

  • DNA-damage-inducible transcript 4 (ddit4) antibody
  • DNA-damage-inducible transcript 4 (DDIT4) antibody
  • DNA-damage-inducible transcript 4 (Ddit4) antibody
  • 5830413E08Rik antibody
  • AA415483 antibody
  • dig2 antibody
  • REDD-1 antibody
  • REDD1 antibody
  • rtp801 antibody
  • sb:cb821 antibody
  • zgc:64114 antibody

Protein level used designations for DDIT4

DNA damage-inducible transcript 4 protein , REDD-1 , DNA-damage-inducible transcript 4 protein , protein regulated in development and DNA damage response 1 , DNA-damage-inducible transcript 4 , HIF-1 responsive protein RTP801 , HIF-1 responsive RTP801 , dexamethasone-induced gene 2 protein , regulated in development and DNA damage response 1

GENE ID SPECIES
394782 Xenopus (Silurana) tropicalis
450520 Pan troglodytes
489038 Canis lupus familiaris
54541 Homo sapiens
74747 Mus musculus
140942 Rattus norvegicus
100153821 Sus scrofa
529235 Bos taurus
379481 Xenopus laevis
378866 Danio rerio
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