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anti-Rat (Rattus) EGFR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended EGFR Antibody (supplied by: Log in to see )

Antigen
Epidermal Growth Factor Receptor (EGFR) Antibodies
  • 9030024J15Rik
  • AI552599
  • C-erb
  • c-erbB
  • CG10079
  • D-Egf
  • d-egf-r
  • D-EGFR
  • Degfr
  • dEgfr
  • DEgfr
  • DEGFR
  • dEGFR
  • dEGFR1
  • der
  • DER
  • Der
  • DER/EGFR
  • DER/faint little ball
  • DER/top
  • DER/torpedo
  • DER1
  • DER flb
  • Dmel\\CG10079
  • DmHD-33
  • EFG-R
  • Egf
  • EGF-R
  • Egf-r
  • EgfR
  • EGfr
  • EGFr
  • EGFR
  • egfr
  • egfr1
  • EGFR12
  • EGFR15
  • EK2-6
  • El
  • Elp
  • Elp-1
  • Elp-B1
  • Elp-B1RB1
  • ERBB
  • Erbb
  • ErbB-1
  • ERBB1
  • Erbb2
  • Errb1
  • Errp
  • flb
  • HD-33
  • HER1
  • l(2)05351
  • l(2)09261
  • l(2)57DEFa
  • l(2)57Ea
  • l(2)57EFa
  • mENA
  • mor1
  • PIG61
  • TOP
  • top
  • top/DER
  • top/flb
  • Torpedo/DER
  • Torpedo/Egfr
  • torpedo/Egfr
  • torpedo/egfr
  • wa-2
  • wa2
  • Wa5
Epitope
pTyr1092
127
56
55
51
51
49
48
45
45
44
44
33
32
30
30
25
23
23
23
22
21
19
18
17
16
16
14
13
13
13
13
13
13
13
13
11
10
10
10
9
9
9
8
8
8
8
8
7
7
7
6
6
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
1700
662
589
21
14
14
12
10
7
7
4
2
1
1
1
Host
Rabbit
1263
393
36
25
4
2
Clonality
Polyclonal
Conjugate
This EGFR antibody is un-conjugated
74
57
45
35
25
25
23
22
21
21
21
21
21
21
20
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
1103
500
380
239
232
205
175
142
86
60
55
54
25
11
9
5
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN498778
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34458184 ABIN498780 IHC (p) Rabbit pTyr1197 Log in to see Polyclonal
0.34458184 ABIN498781 IHC (p) Rabbit pTyr869 Log in to see Polyclonal
0.34458184 ABIN498782 IHC (p) Rabbit pTyr1110 Log in to see Polyclonal
0.34458184 ABIN498727 IHC (p) WB Rabbit pTyr1197 Log in to see Polyclonal
0.34458184 ABIN498779 IHC (p) Rabbit pTyr1172 Log in to see Polyclonal
0.34458184 ABIN498870 IHC (p) Rabbit Log in to see Polyclonal
0.34458184 ABIN498871 IHC (p) Rabbit Log in to see Polyclonal
0.34458184 ABIN498873 IHC (p) Rabbit Log in to see Polyclonal
0.34458184 ABIN498869 IHC (p) Rabbit Log in to see Polyclonal
0.34458184 ABIN498872 IHC (p) Rabbit Log in to see Polyclonal
0.34458184 ABIN615211 IF IHC (p) IP WB Sheep Internal Region Log in to see Polyclonal
0.00089488085 ABIN401341 EIA IHC (p) WB Rabbit IgG AA 1189-1199, pTyr1197 Log in to see Polyclonal 4
0.00089488085 ABIN118051 EIA IHC (p) IP WB Rabbit AA 1168-1180 Log in to see Polyclonal 1
0.00089488085 ABIN197228 IF IHC (p) WB Rabbit AA 1068-1072 Log in to see Polyclonal 4
0.00089488085 ABIN196960 IHC (p) WB Rabbit pTyr1172 Log in to see Polyclonal 5
0.00089488085 ABIN197516 IHC (p) WB Rabbit Tyr1110 Log in to see Polyclonal 3
0.00089488085 ABIN197230 IHC (p) WB Rabbit Tyr1092 Log in to see Polyclonal 5
0.00089488085 ABIN272018 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089488085 ABIN265397 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089488085 ABIN265396 EIA IHC (p) WB Rabbit Log in to see Polyclonal

Similar anti-EGFR Antibodies

Application / Reactivity Human Rat (Rattus)
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Radioimmunoassay (RIA) 1 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Neutralization (Neut) 3 Antibodies
Luminex Assay (LMNX) 11 Antibodies
Intracellular Staining (ICS) 2 Antibodies 2 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Inhibition Assay (InhA) 2 Antibodies
Indirect Immunofluorescence Assay (IFA) 2 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 216 Antibodies 22 Antibodies
Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 255 Antibodies 83 Antibodies

General

Antigen Epidermal Growth Factor Receptor (EGFR) Antibodies
Epitope pTyr1092
(127), (56), (55), (51), (51), (49), (48), (45), (45), (44), (44), (33), (32), (30), (30), (25), (23), (23), (23), (22), (21), (19), (18), (17), (16), (16), (14), (13), (13), (13), (13), (13), (13), (13), (13), (11), (10), (10), (10), (9), (9), (9), (8), (8), (8), (8), (8), (7), (7), (7), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(1700), (662), (589), (21), (14), (14), (12), (10), (7), (7), (4), (2), (1), (1), (1)
Host Rabbit
(1263), (393), (36), (25), (4), (2)
Clonality
Polyclonal
Conjugate This EGFR antibody is un-conjugated
(74), (57), (45), (35), (25), (25), (23), (22), (21), (21), (21), (21), (21), (21), (20), (2), (2), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(1103), (500), (380), (239), (232), (205), (175), (142), (86), (60), (55), (54), (25), (11), (9), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-EGFR Antibody

Target Details EGFR Application Details Handling Images
Specificity This antibody detects endogenous levels of p-EGFR protein only when phosphorylated at Tyr1068 (removal of the signal peptide).
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details EGFR

Product Details anti-EGFR Antibody Application Details Handling Images back to top
Antigen
Alternative Name EGFR / ERBB1 (EGFR Antibody Abstract)
Background Epidermal growth factor mediates its effects on cell growth through its interaction with a cell surface glycoprotein designated the EGF receptor. Binding of EGF or TGFalpha to the EGF receptor activates tyrosine-specific protein kinase activity intrinsic to the EGF receptor. The carboxy-terminal tyrosine residues on EGFR, Tyr 1068 and Tyr 1173, are the major sites of autophosphorylation, which occurs as a result of EGF binding. Once activated, EGFR mediates the binding of the phosphotyrosine binding (PTB) domain of GRB2 through direct interactions with Tyr 1068 and Tyr 1086 and through indirect interactions with Tyr 1173 in the Ras signaling pathway. Tyr 1173 of EGFR also functions as a kinase substrate. Phosphorylation of Tyr 992, Tyr 1068 and Tyr 1086 is required for conformational change in the C-terminal tail of the EGF receptorgulates Actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
Molecular Weight approx. 175 kDa
Gene ID 1956
NCBI Accession NP_005219
UniProt P00533
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-EGFR Antibody Target Details EGFR Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-EGFR Antibody Target Details EGFR Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.09 % sodium azide, 50 % Glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-EGFR Antibody Target Details EGFR Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EGFR antibody (Epidermal Growth Factor Receptor) (pTyr1092) (ABIN498778) Immunohistochemistry (IHC) analyzes of p-EGFR antibody in paraffin-e...