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anti-Human IKBKG antibody for Immunoprecipitation

Recommended IKBKG Antibody (supplied by: Log in to see )

Antigen
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) Antibodies
  • 1110037D23Rik
  • AI848108
  • AI851264
  • AMCBX1
  • AW124339
  • CG16910
  • dIKK
  • dIKK-gamma
  • Dmel\\CG16910
  • DmIKK-gamma
  • dmIKKgamma
  • Dmikkgamma
  • DmIKKgamma
  • FIP-3
  • FIP3
  • Fip3p
  • fj33c07
  • IKBKG
  • IKBKG_1
  • IKBKG_2
  • IKK
  • IKK-gamma
  • IKKg
  • IKKgamma
  • IKK[g]
  • IKK[[gamma]]
  • IP
  • IP1
  • IP2
  • IPD2
  • Kenny
  • Key
  • KEY
  • MGC97885
  • nemo
  • Nemo
  • NEMO
  • wu:fj33c07
  • ZC2HC9
  • zgc:113492
Epitope
AA 262-319
31
29
28
17
13
11
11
9
8
7
6
5
5
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
307
95
63
5
4
4
2
2
2
2
2
2
1
1
Host
Mouse
222
91
2
2
1
Clonality
Monoclonal
Conjugate
This IKBKG antibody is un-conjugated
11
10
8
6
6
6
4
4
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
243
113
73
45
42
39
25
23
4
4
3
1
1
1
Supplier
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Catalog No. ABIN567775
$ 346.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008957968 ABIN967646 IP WB Mouse IgG1, kappa Log in to see C73 7
0.0008957968 ABIN3198156 IC IF IHC IP WB Rabbit Log in to see Polyclonal
0.0008957968 ABIN2745538 IP ELISA WB Rabbit AA 40-210 Log in to see Polyclonal
0.0008957968 ABIN2972911 ICC IF IP WB Rabbit Center Log in to see Polyclonal

Top referenced anti-IKBKG antibody for Immunoprecipitation

Similar anti-IKBKG Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 13 Antibodies 20 Antibodies
Immunochromatography (IC) 2 Antibodies 2 Antibodies
Immunocytochemistry (ICC) 11 Antibodies 12 Antibodies
Immunofluorescence (IF) 9 Antibodies 12 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 15 Antibodies 18 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies 12 Antibodies
Immunoprecipitation (IP) 3 Antibodies 5 Antibodies
Western Blotting (WB) 38 Antibodies

General

Antigen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) Antibodies
Epitope AA 262-319
(31), (29), (28), (17), (13), (11), (11), (9), (8), (7), (6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(307), (95), (63), (5), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1)
Host Mouse
(222), (91), (2), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IKBKG antibody is un-conjugated
(11), (10), (8), (6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(243), (113), (73), (45), (42), (39), (25), (23), (4), (4), (3), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-IKBKG Antibody

Target Details IKBKG Application Details Handling References for anti-IKBKG Antibody (ABIN567775) Images
Specificity This antibody reacts with IKKG (45 kDa) on Western blotting.
Purification Protein-A Agarose Chromatography of hybridoma supernatant.
Immunogen Human recombinant GST-IKKG (a.a. 262-319).
Clone EA2-6
Isotype IgG1

Target Details IKBKG

Product Details anti-IKBKG Antibody Application Details Handling References for anti-IKBKG Antibody (ABIN567775) Images back to top
Antigen
Alternative Name NEMO / IKBKG (IKBKG Antibody Abstract)
Background The I-kB kinase complex (IKK) functions as a mediator of NF-kB activation in response to multiple stimuli by phosphorylating I-kB inhibitor proteins and causing their degradation. IKK contains two structurally related catalytic subunits termed IKKA and IKKB as well as a noncatalytic subunit called IKKG/NEMO. IKK is composed of a IKKG/NEMO homodimer bound together with either an IKKA/IKKB heterodimer or an IKKB homodimer. Although IKKG /NEMO itself does not have kinase activity, it is essential for NF-kB activation likely via a scaffold function that is required for IKK activity. Mutations in the X-linked gene encoding IKKG can interfere with NF-kB signaling and lead to immunodeficiency disease.Synonyms: FIP-3, FIP3, I-kappa-B kinase subunit gamma, IKK-gamma, IKKAP1, IKKG, IkB kinase subunit gamma, IkB kinase-associated protein 1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, NF-kappa-B essential modifier, NF-kappa-B essential modulator
Gene ID 8517
NCBI Accession NP_001093326
UniProt Q9Y6K9
Pathways NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-IKBKG Antibody Target Details IKBKG Handling References for anti-IKBKG Antibody (ABIN567775) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IKBKG Antibody Target Details IKBKG Application Details References for anti-IKBKG Antibody (ABIN567775) Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 50 % Glycerol without preservatives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20 °C.

References for anti-IKBKG Antibody (ABIN567775)

Product Details anti-IKBKG Antibody Target Details IKBKG Application Details Handling Images back to top
Background publications

Iha, Kibler, Yedavalli, Peloponese, Haller, Miyazato, Kasai, Jeang: "Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling." in: Oncogene, Vol. 22, Issue 55, pp. 8912-23, 2003

Chu, Shin, Yang, DiDonato, Ballard: "IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1." in: The Journal of biological chemistry, Vol. 274, Issue 22, pp. 15297-300, 1999

Images

Product Details anti-IKBKG Antibody Target Details IKBKG Application Details Handling References for anti-IKBKG Antibody (ABIN567775) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-IKBKG antibody (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma) (AA 262-319) (ABIN567775) anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) (AA 262-319) antibody
Western Blotting (WB) image for anti-IKBKG antibody (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma) (AA 262-319) (ABIN567775) anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) (AA 262-319) antibody (Image 2)
Western Blotting (WB) image for anti-IKBKG antibody (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma) (AA 262-319) (ABIN567775) anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) (AA 262-319) antibody (Image 3)