anti-Mouse (Murine) IL1B antibody for Neutralization

Recommended IL1B Antibody (supplied by: Log in to see )

Antigen
Interleukin 1, beta (IL1B) Antibodies
  • il1-b
  • zgc:111873
  • IL-1beta
  • Il-1b
  • IL1B
  • IL-1
  • IL1-BETA
  • IL1F2
  • IL-1BETA
  • IL1beta
  • IL-1B
  • interleukin 1, beta
  • interleukin 1 beta
  • il1b
  • Il1b
  • IL-1B
  • IL1B
Reactivity
Mouse (Murine)
546
192
128
37
31
20
17
13
13
12
8
7
6
4
4
2
2
2
1
1
Host
Rabbit
409
367
19
19
8
7
6
2
2
Clonality
Polyclonal
Conjugate
This IL1B antibody is un-conjugated
96
46
33
26
15
14
12
12
10
10
9
8
8
8
8
8
8
8
4
4
4
4
4
4
4
2
2
1
1
1
1
1
1
1
1
Application
Neutralization (Neut), Western Blotting (WB)
524
415
176
160
112
75
59
54
46
32
31
24
16
14
14
7
6
5
4
4
3
3
3
3
2
1
1
1
1
1
1
1
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Catalog No. ABIN223538
$ 285.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN964790 FACS IP IHC Neut RIA ELISA WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN964782 FACS IP IHC Neut RIA ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN1176987 IP Neut ELISA Armenian Hamster IgG, lambda Log in to see B122 4
1 ABIN5556655 EIA IF IHC (fro) IHC (p) IP Neut RIA WB Rabbit Log in to see Polyclonal
1 ABIN964792 FACS IP IHC Neut RIA ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN465876 ELISA IHC Neut WB Biotin Rabbit Log in to see Polyclonal
1 ABIN465863 IHC Neut ELISA WB Rabbit Log in to see Polyclonal
1 ABIN2689747 IP Neut ELISA WB Armenian Hamster IgG, lambda Log in to see B122 2
1 ABIN4224491 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN4224492 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN476584 Neut ELISA Hamster IgG Log in to see B122
1 ABIN208677 Neut ELISA Rat IgG1 Log in to see
1 ABIN4224489 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN4224488 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN208674 Neut ELISA Rat IgG1 Log in to see
1 ABIN208678 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN4965355 Neut WB Rabbit IgG Log in to see Polyclonal
1 ABIN2742005 Neut IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN4224490 BP ELISA Neut Allophycocyanin Mouse Log in to see 1400-24-17
1 ABIN346631 Neut ELISA WB Rabbit Log in to see Polyclonal

General

Antigen Interleukin 1, beta (IL1B) Antibodies
Reactivity Mouse (Murine)
(546), (192), (128), (37), (31), (20), (17), (13), (13), (12), (8), (7), (6), (4), (4), (2), (2), (2), (1), (1)
Host Rabbit
(409), (367), (19), (19), (8), (7), (6), (2), (2)
Clonality
Polyclonal
Conjugate This IL1B antibody is un-conjugated
(96), (46), (33), (26), (15), (14), (12), (12), (10), (10), (9), (8), (8), (8), (8), (8), (8), (8), (4), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Neutralization (Neut), Western Blotting (WB)
(524), (415), (176), (160), (112), (75), (59), (54), (46), (32), (31), (24), (16), (14), (14), (7), (6), (5), (4), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-IL1B Antibody

Target Details IL1B Application Details Handling References for anti-IL1B antibody (ABIN223538) Images
Purification Affinity purified
Immunogen E. coli expressed murine IL-1beta
Isotype IgG

Target Details IL1B

Product Details anti-IL1B Antibody Application Details Handling References for anti-IL1B antibody (ABIN223538) Images back to top
Antigen
Alternative Name IL-1b (IL1B Antibody Abstract)
Background IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant murine IL-1beta is a 17.5 kDa protein containing 153 amino acid residues.
Synonyms: IL-1 beta, IL1 beta, IL 1 beta, Interluekin-1 beta, Interluekin 1 beta, interluekin
Gene ID 52667
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways NF-kappaB Signaling, Interferon-gamma Pathway, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy

Application Details

Product Details anti-IL1B Antibody Target Details IL1B Handling References for anti-IL1B antibody (ABIN223538) Images back to top
Application Notes Western blot analysis (0.5-4 μg/mL). Recombinant murine IL-1β can be used as a positive control. Per researcher's feedback, the antibody can also be used in neutralization studies. However, the optimal conditions should be determined individually.
Restrictions For Research Use only

Handling

Product Details anti-IL1B Antibody Target Details IL1B Application Details References for anti-IL1B antibody (ABIN223538) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti-murine IL-1β polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 %BSA and 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-IL1B antibody (ABIN223538)

Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling Images back to top
Product cited in:

Wang, Viollet, Terkeltaub, Liu-Bryan: "AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages." in: Annals of the rheumatic diseases, 2014

Zhang, Xu, Ma, Wu, Wang, Zhou, Han: "Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 7, pp. 3517-24, 2013

Martin, Shaw, Liu, Steiger, Harper: "MSU crystal-recruited non-inflammatory monocytes differentiate into M1-like pro-inflammatory macrophages in a peritoneal murine model of gout." in: Arthritis and rheumatism, 2011

Martin, Shaw, Liu, Steiger, Harper: "Monosodium urate monohydrate crystal-recruited noninflammatory monocytes differentiate into M1-like proinflammatory macrophages in a peritoneal murine model of gout." in: Arthritis and rheumatism, Vol. 63, Issue 5, pp. 1322-32, 2011

Sozen, Tsuchiyama, Hasegawa, Suzuki, Jadhav, Nishizawa, Zhang: "Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice." in: Stroke; a journal of cerebral circulation, Vol. 40, Issue 7, pp. 2519-25, 2009

Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: "Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 9, pp. 6370-8, 2006

Images

Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling References for anti-IL1B antibody (ABIN223538) back to top
Supplier Images
 image for anti-Interleukin 1, beta (IL1B) antibody (ABIN223538) anti-Interleukin 1, beta (IL1B) antibody