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anti-Mouse (Murine) IL1B antibody for Neutralization

Recommended IL1B Antibody (supplied by: Log in to see )

Antigen
Interleukin 1, beta (IL1B) Antibodies
  • il1-b
  • zgc:111873
  • IL-1beta
  • Il-1b
  • IL1B
  • IL-1
  • IL1-BETA
  • IL1F2
  • IL-1BETA
  • IL1beta
  • IL-1B
  • interleukin 1, beta
  • interleukin 1 beta
  • il1b
  • Il1b
  • IL-1B
  • IL1B
Reactivity
Mouse (Murine)
519
165
121
38
26
20
17
12
12
10
8
7
6
3
3
2
2
2
1
1
Host
Rabbit
404
342
17
16
8
8
6
3
2
Clonality
Polyclonal
Conjugate
This IL1B antibody is un-conjugated
100
47
35
22
13
12
11
10
8
8
8
8
8
8
8
8
8
4
4
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Neutralization (Neut), Western Blotting (WB)
503
416
154
125
113
70
69
47
38
29
27
24
13
12
7
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
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Catalog No. ABIN223538
$ 325.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN964790 FACS IP IHC Neut RIA ELISA WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN1176987 IP Neut ELISA Armenian Hamster IgG, lambda Log in to see B122 4
1 ABIN964782 FACS IP IHC Neut RIA ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN616079 EIA IHC (fro) IF IHC (p) IP Neut RIA WB Rabbit Log in to see Polyclonal 3
1 ABIN964792 FACS IP IHC Neut RIA ELISA WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN2689747 IP Neut ELISA WB Armenian Hamster IgG, lambda Log in to see B122 2
1 ABIN465863 IHC Neut ELISA WB Rabbit Log in to see Polyclonal
1 ABIN476584 Neut ELISA Hamster IgG Log in to see B122
1 ABIN208678 Neut ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN208674 Neut ELISA Rat IgG1 Log in to see
1 ABIN208677 Neut ELISA Rat IgG1 Log in to see
1 ABIN4965355 Neut WB Rabbit IgG Log in to see Polyclonal
1 ABIN346631 Neut ELISA WB Rabbit Log in to see Polyclonal
1 ABIN4224492 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN4224491 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN2291040 Neut WB Rabbit IgG Log in to see Polyclonal
1 ABIN4224489 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN4224488 BP ELISA Neut Mouse Log in to see 1400-24-17
1 ABIN242199 Neut ELISA WB Rabbit Log in to see Polyclonal
1 ABIN4224490 BP ELISA Neut Allophycocyanin Mouse Log in to see 1400-24-17

Top referenced anti-IL1B antibody for Neutralization

Similar anti-IL1B Antibodies

Application / Reactivity Mouse (Murine)
Blocking Antibody (Inhibition) 2 Antibodies
Blocking Peptide (BP) 5 Antibodies
Electron Microscopy (EM) 1 Antibodies
ELISA 84 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 19 Antibodies
Functional Studies (Func) 6 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 7 Antibodies
Immunofluorescence (IF) 8 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies
Immunohistochemistry (IHC) 46 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 31 Antibodies
Immunoprecipitation (IP) 14 Antibodies
Intracellular Flow Cytometry (ICFC) 1 Antibodies

General

Antigen Interleukin 1, beta (IL1B) Antibodies
Reactivity Mouse (Murine)
(519), (165), (121), (38), (26), (20), (17), (12), (12), (10), (8), (7), (6), (3), (3), (2), (2), (2), (1), (1)
Host Rabbit
(404), (342), (17), (16), (8), (8), (6), (3), (2)
Clonality
Polyclonal
Conjugate This IL1B antibody is un-conjugated
(100), (47), (35), (22), (13), (12), (11), (10), (8), (8), (8), (8), (8), (8), (8), (8), (8), (4), (4), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Neutralization (Neut), Western Blotting (WB)
(503), (416), (154), (125), (113), (70), (69), (47), (38), (29), (27), (24), (13), (12), (7), (5), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-IL1B Antibody

Target Details IL1B Application Details Handling References for anti-IL1B Antibody (ABIN223538) Images
Purification Affinity purified
Immunogen E. coli expressed murine IL-1beta
Isotype IgG

Target Details IL1B

Product Details anti-IL1B Antibody Application Details Handling References for anti-IL1B Antibody (ABIN223538) Images back to top
Antigen
Alternative Name IL-1b (IL1B Antibody Abstract)
Background IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant murine IL-1beta is a 17.5 kDa protein containing 153 amino acid residues.
Synonyms: IL-1 beta, IL1 beta, IL 1 beta, Interluekin-1 beta, Interluekin 1 beta, interluekin
Gene ID 52667
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Pathways NF-kappaB Signaling, TCR Signaling, Interferon-gamma Pathway

Application Details

Product Details anti-IL1B Antibody Target Details IL1B Handling References for anti-IL1B Antibody (ABIN223538) Images back to top
Application Notes Western blot analysis (0.5-4 μg/mL). Neutralization studies.
Recombinant murine IL-1β can be used as a positive control.
However, the optimal conditions should be determined individually.
Comment

Country of Animal Origin: China

Restrictions For Research Use only

Handling

Product Details anti-IL1B Antibody Target Details IL1B Application Details References for anti-IL1B Antibody (ABIN223538) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer 100 μg (0.5 mg/mL) affinity purified rabbit anti-murine IL-1β polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30 % glycerol, 0.5 %BSA and 0.01 % thimerosal.
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice The antibody solution should be gently mixed before use.
Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment For long-term storage, aliquot and freeze at -70 °C.
Expiry Date 12 months

References for anti-IL1B Antibody (ABIN223538)

Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling Images back to top
Product cited in:

Wang, Viollet, Terkeltaub, Liu-Bryan: "AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages." in: Annals of the rheumatic diseases, 2014

Zhang, Xu, Ma, Wu, Wang, Zhou, Han: "Gene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 7, pp. 3517-24, 2013

Martin, Shaw, Liu, Steiger, Harper: "MSU crystal-recruited non-inflammatory monocytes differentiate into M1-like pro-inflammatory macrophages in a peritoneal murine model of gout." in: Arthritis and rheumatism, 2011

Martin, Shaw, Liu, Steiger, Harper: "Monosodium urate monohydrate crystal-recruited noninflammatory monocytes differentiate into M1-like proinflammatory macrophages in a peritoneal murine model of gout." in: Arthritis and rheumatism, Vol. 63, Issue 5, pp. 1322-32, 2011

Sozen, Tsuchiyama, Hasegawa, Suzuki, Jadhav, Nishizawa, Zhang: "Role of interleukin-1beta in early brain injury after subarachnoid hemorrhage in mice." in: Stroke; a journal of cerebral circulation, Vol. 40, Issue 7, pp. 2519-25, 2009

Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: "Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 9, pp. 6370-8, 2006

Images

Product Details anti-IL1B Antibody Target Details IL1B Application Details Handling References for anti-IL1B Antibody (ABIN223538) back to top
Supplier Images
 image for anti-IL1B antibody (Interleukin 1, beta) (ABIN223538) anti-Interleukin 1, beta (IL1B) antibody