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anti-Human IL1RAP antibody for Flow Cytometry

Recommended IL1RAP Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 Receptor Accessory Protein (IL1RAP) Antibodies
  • 6430709H04Rik
  • AI255955
  • AV239853
  • C3orf13
  • IL-1RAcp
  • IL-1RAcP
  • il-1racp
  • il-racp
  • il1r3
  • IL1R3
  • Il1racpb
  • IL1RAP
Epitope
AA 1-359
10
7
6
5
4
3
3
3
3
1
1
1
Reactivity
Human
55
15
12
1
Host
Mouse
48
10
Clonality
Monoclonal
Conjugate
This IL1RAP antibody is un-conjugated
3
2
1
1
1
Minimum Detection Limit
0.16 ng/well
Application
Flow Cytometry (FACS), ELISA
42
29
8
6
4
3
3
3
2
1
Supplier
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Catalog No. ABIN1995735
$ 218.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3068567 ABIN1995738 FACS FITC Mouse IgG2a AA 1-359 Log in to see 5
0.3068567 ABIN1995740 FACS PE Mouse IgG2a AA 1-359 Log in to see
0.0010666476 ABIN2298351 FACS ELISA PerCP Mouse IgG1 AA 21-359 Log in to see 89412
0.0010666476 ABIN2682159 FACS APC Mouse Log in to see

Similar anti-IL1RAP Antibodies

Application / Reactivity Human
ELISA 30 Antibodies
Flow Cytometry (FACS) 5 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 6 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunohistochemistry (IHC) 6 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 42 Antibodies

General

Antigen Interleukin 1 Receptor Accessory Protein (IL1RAP) Antibodies
Epitope AA 1-359
(10), (7), (6), (5), (4), (3), (3), (3), (3), (1), (1), (1)
Reactivity Human
(55), (15), (12), (1)
Host Mouse
(48), (10)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL1RAP antibody is un-conjugated
(3), (2), (1), (1), (1)
Minimum Detection Limit 0.16 ng/well
Application Flow Cytometry (FACS), ELISA
(42), (29), (8), (6), (4), (3), (3), (3), (2), (1)
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Product Details anti-IL1RAP Antibody

Target Details IL1RAP Application Details Handling Images
Specificity Human IL1R3 / IL1RAP
Cross-Reactivity (Details) No cross-reactivity with Human cell lysate (293 cell line) in WB and ELISA.
Characteristics This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1R3 / IL1RAP (rh IL1R3, NP_002173.1, Met 1-Glu 359). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Sterility 0.2 μm filtered
Clone 7E4G1E8
Isotype IgG2a

Target Details IL1RAP

Product Details anti-IL1RAP Antibody Application Details Handling Images back to top
Antigen
Alternative Name IL1RAP (IL1RAP Antibody Abstract)
Background Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a a cytokine receptor which binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. IL-1RAcP/IL-1R3 is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. IL-1RAcP/IL-1R3 mediates interleukin-1-dependent activation of NF-kappa-B. Isoform 1 is part of the membrane-bound form of the IL-1 receptor. Signaling involves formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. Isoform 2 modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
NCBI Accession NP_002173.1
Research Area Cardiovascular, Atherosclerosis, Innate Immunity, Cytokines
Pathways NF-kappaB Signaling

Application Details

Product Details anti-IL1RAP Antibody Target Details IL1RAP Handling Images back to top
Application Notes ELISA ELISA: 0.5-1 μg/mL This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human IL1R3. The detection limit for Human IL1R3 is 0.16 ng/well.
Restrictions For Research Use only

Handling

Product Details anti-IL1RAP Antibody Target Details IL1RAP Application Details Images back to top
Concentration 0.77µg/µl
Buffer PBS with 5% trehalose
Preservative Without preservative
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C/-20 °C/-80 °C
Storage Comment This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -70°C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly.
Expiry Date 12 months

Images

Product Details anti-IL1RAP Antibody Target Details IL1RAP Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-IL1RAP antibody (Interleukin 1 Receptor Accessory Protein) (AA 1-359) (ABIN1995735) anti-Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 1-359) antibody