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anti-Mouse (Murine) MYD88 antibody for Enzyme Immunoassay

Recommended MYD88 Antibody (supplied by: Log in to see )

Antigen
Myeloid Differentiation Primary Response Gene (88) (MYD88) Antibodies
  • XMyD88
  • myd88d
  • MGC84928
  • CG2078
  • DMMYD88
  • DmMyD88
  • DmMyd88
  • Dmel\\CG2078
  • EP(2)2535
  • Kra
  • LD20892
  • MYD88
  • MyD88
  • Myd88F
  • dMyD88
  • dMyd88
  • kra
  • myd88
  • zgc:103541
  • GB12344
  • NV10640
  • irak-2
  • MYD88D
  • myeloid differentiation primary response gene (88)
  • CG2078 gene product from transcript CG2078-RB
  • myeloid differentiation primary response factor 88
  • myeloid differentiation primary response 88
  • myeloid differentiation primary response gene 88
  • MyD88 adaptor
  • myeloid differentiation factor 88
  • myeloid differentiation response protein 88
  • interleukin-1 receptor-associated kinase 2
  • myd88-b
  • Myd88
  • myd88
  • IRAK2
  • irak2
  • LOC100228175
  • MYD88
Epitope
C-Term
28
20
19
17
16
15
13
10
7
6
6
5
4
3
3
3
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
252
106
54
7
4
4
3
3
2
2
1
1
1
1
1
1
Host
Rabbit
170
67
20
8
Clonality
Polyclonal
Conjugate
This MYD88 antibody is un-conjugated
9
7
6
5
5
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
223
82
68
62
55
44
36
11
9
4
3
2
2
2
1
1
1
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Catalog No. ABIN401364
$ 456.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN453754 EIA WB Rabbit Middle Region Log in to see Polyclonal 2
1 ABIN374527 EIA IHC (p) WB Goat Internal Region Log in to see Polyclonal 1
1 ABIN500300 EIA IHC (p) WB Rabbit IgG AA 233-248 Log in to see Polyclonal 2
1 ABIN500302 EIA WB Rabbit IgG AA 279-296, C-Term Log in to see Polyclonal 4
1 ABIN493143 DB EIA IHC (fro) WB Rabbit N-Term Log in to see Polyclonal 3
1 ABIN492527 EIA IHC (p) WB Mouse IgG AA 176-280 Log in to see 2E9C2
1 ABIN2563994 EIA IHC ELISA WB Goat IgG Internal Region Log in to see Polyclonal

Top referenced anti-MYD88 antibody for Enzyme Immunoassay

Similar anti-MYD88 Antibodies

Application / Reactivity Mouse (Murine) Human
Cytometry by Time of Flight (CyTOF) 2 Antibodies 2 Antibodies
Dot Blot (DB) 1 Antibodies 1 Antibodies
ELISA 24 Antibodies 76 Antibodies
Enzyme Immunoassay (EIA) 8 Antibodies
Flow Cytometry (FACS) 23 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 23 Antibodies
Immunofluorescence (IF) 25 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 29 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 16 Antibodies
Immunoprecipitation (IP) 1 Antibodies
SDS-PAGE (SDS) 1 Antibodies
Simple Western (SimWes) 1 Antibodies
Western Blotting (WB) 88 Antibodies

General

Antigen Myeloid Differentiation Primary Response Gene (88) (MYD88) Antibodies
Epitope C-Term
(28), (20), (19), (17), (16), (15), (13), (10), (7), (6), (6), (5), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(252), (106), (54), (7), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(170), (67), (20), (8)
Clonality
Polyclonal
Conjugate This MYD88 antibody is un-conjugated
(9), (7), (6), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(223), (82), (68), (62), (55), (44), (36), (11), (9), (4), (3), (2), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-MYD88 Antibody

Target Details MYD88 Application Details Handling References for anti-MYD88 Antibody (ABIN401364) Images
Specificity This antibody reacts to MYD88.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity Purified
Immunogen Synthetic peptide corresponding to a region near the carboxy terminus of human MyD88 protein
Isotype IgG

Target Details MYD88

Product Details anti-MYD88 Antibody Application Details Handling References for anti-MYD88 Antibody (ABIN401364) Images back to top
Antigen
Alternative Name MYD88 (MYD88 Antibody Abstract)
Background MyD88 (Myeloid differentiation primary response protein). The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. Recently, MyD88 was identified as an adapter molecule in the IL-1 signaling pathway (1). MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and the dominant negative form of MyD88 attenuates IL-1R-mediated NF-kappaΒ activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor (2,3), both members of the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in loss of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to the bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors. MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. The MyD88 gene is expressed in many tissues.Synonyms: Myeloid differentiation primary response protein MyD88
Gene ID 4615
NCBI Accession NP_001166037
UniProt Q99836
Pathways NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-MYD88 Antibody Target Details MYD88 Handling References for anti-MYD88 Antibody (ABIN401364) Images back to top
Application Notes ELISA: 1/5000 - 1/20000. Western Blot: 1/500 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MYD88 Antibody Target Details MYD88 Application Details References for anti-MYD88 Antibody (ABIN401364) Images back to top
Concentration 0.5 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.02 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

References for anti-MYD88 Antibody (ABIN401364)

Product Details anti-MYD88 Antibody Target Details MYD88 Application Details Handling Images back to top
Background publications

Kawai, Adachi, Ogawa, Takeda, Akira: "Unresponsiveness of MyD88-deficient mice to endotoxin." in: Immunity, Vol. 11, Issue 1, pp. 115-22, 1999

Adachi, Kawai, Takeda, Matsumoto, Tsutsui, Sakagami, Nakanishi, Akira: "Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function." in: Immunity, Vol. 9, Issue 1, pp. 143-50, 1998

Medzhitov, Preston-Hurlburt, Kopp, Stadlen, Chen, Ghosh, Janeway: "MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways." in: Molecular cell, Vol. 2, Issue 2, pp. 253-8, 1998

Bonnert, Garka, Parnet, Sonoda, Testa, Sims: "The cloning and characterization of human MyD88: a member of an IL-1 receptor related family." in: FEBS letters, Vol. 402, Issue 1, pp. 81-4, 1997

Muzio, Ni, Feng, Dixit: "IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling." in: Science (New York, N.Y.), Vol. 278, Issue 5343, pp. 1612-5, 1997

Images

Product Details anti-MYD88 Antibody Target Details MYD88 Application Details Handling References for anti-MYD88 Antibody (ABIN401364) back to top
Supplier Images
 image for anti-MYD88 antibody (Myeloid Differentiation Primary Response Gene (88)) (C-Term) (ABIN401364) anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (C-Term) antibody