anti-Rat (Rattus) MYD88 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended MYD88 Antibody (supplied by: Log in to see )

Antigen
Myeloid Differentiation Primary Response Gene (88) (MYD88) Antibodies
  • MYD88D
  • irak-2
  • XMyD88
  • myd88d
  • MGC84928
  • CG2078
  • DMMYD88
  • DmMyD88
  • DmMyd88
  • Dmel\\CG2078
  • EP(2)2535
  • Kra
  • LD20892
  • MYD88
  • MyD88
  • Myd88F
  • dMyD88
  • dMyd88
  • kra
  • myd88
  • zgc:103541
  • GB12344
  • NV10640
  • myeloid differentiation primary response 88
  • interleukin-1 receptor-associated kinase 2
  • myeloid differentiation primary response gene (88)
  • myeloid differentiation primary response gene 88
  • CG2078 gene product from transcript CG2078-RB
  • myeloid differentiation primary response factor 88
  • MyD88 adaptor
  • myeloid differentiation factor 88
  • myeloid differentiation response protein 88
  • MYD88
  • irak2
  • IRAK2
  • LOC100228175
  • myd88-b
  • Myd88
  • myd88
Epitope
AA 240-290
29
24
20
16
14
12
12
12
8
6
5
5
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
264
138
74
12
8
7
7
6
6
6
4
2
2
1
1
1
Host
Rabbit
170
68
23
22
Clonality
Polyclonal
Conjugate
This MYD88 antibody is un-conjugated
11
8
7
6
6
5
5
5
4
4
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
229
85
80
64
59
49
37
12
9
9
8
4
4
2
2
1
1
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Catalog No. ABIN736881
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN736886 IF (p) Cy5.5 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN736884 IF (p) Cy3 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN736888 IF (p) FITC Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN907427 IF (p) Alexa Fluor 555 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN907428 IF (p) Alexa Fluor 350 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN2804402 IF (p) Alexa Fluor 594 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN736885 IF (p) Cy5 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN907430 IF (p) Alexa Fluor 647 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN736887 IF (p) Cy7 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN907429 IF (p) Alexa Fluor 488 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN5007182 IF (p) Alexa Fluor 680 Rabbit IgG AA 240-290 Log in to see Polyclonal
1 ABIN5007183 IF (p) Alexa Fluor 750 Rabbit IgG AA 240-290 Log in to see Polyclonal

General

Antigen Myeloid Differentiation Primary Response Gene (88) (MYD88) Antibodies
Epitope AA 240-290
(29), (24), (20), (16), (14), (12), (12), (12), (8), (6), (5), (5), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(264), (138), (74), (12), (8), (7), (7), (6), (6), (6), (4), (2), (2), (1), (1), (1)
Host Rabbit
(170), (68), (23), (22)
Clonality
Polyclonal
Conjugate This MYD88 antibody is un-conjugated
(11), (8), (7), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(229), (85), (80), (64), (59), (49), (37), (12), (9), (9), (8), (4), (4), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-MYD88 Antibody

Target Details MYD88 Application Details Handling References for anti-MYD88 antibody (ABIN736881) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse MyD88
Isotype IgG

Target Details MYD88

Product Details anti-MYD88 Antibody Application Details Handling References for anti-MYD88 antibody (ABIN736881) Images back to top
Antigen
Alternative Name Myd88 (MYD88 Antibody Abstract)
Background

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS). Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.

Subcellular location: Cytoplasm

Synonyms: Myeloid differentiation primary response protein MyD88, Myd88

Gene ID 17874
UniProt P22366
Research Area Immunology, Innate Immunity, Atherosclerosis
Pathways NF-kappaB Signaling, TLR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-MYD88 Antibody Target Details MYD88 Handling References for anti-MYD88 antibody (ABIN736881) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-MYD88 Antibody Target Details MYD88 Application Details References for anti-MYD88 antibody (ABIN736881) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-MYD88 antibody (ABIN736881)

Product Details anti-MYD88 Antibody Target Details MYD88 Application Details Handling Images back to top
Product cited in:

Fu, Xia, Liu, Wang, Wang, Shi, Song, Song, Song et al.: "The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin ..." in: Toxicology, Vol. 381, pp. 39-50, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Fu, Shi, Song, Liu, Wang, Wang, Song, Song: "From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 153, Issue 2, pp. 303-15, 2016

Chen, Ye, Zhang, Tang, Li, Lu, Wu, Yu, Kou: "Limb Remote Ischemic Postconditioning Reduces Ischemia-Reperfusion Injury by Inhibiting NADPH Oxidase Activation and MyD88-TRAF6-P38MAP-Kinase Pathway of Neutrophils." in: International journal of molecular sciences, Vol. 17, Issue 12, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Wang, Shi, Lv, Xu, Li, Ge, Xiao, Geng, Liu: "Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-?B Activation in Microglial Cells." in: Inflammation, 2015

Lu, Liu, Gu, Ge, Wu, Ze-Ji, Qiu, Zhang, Chao, Yu: "Gene Expression Profiles Underlying Selective T-Cell-Mediated Immunity Activity of a Chinese Medicine Granule on Mice Infected with Influenza Virus H1N1." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 976364, 2014

Images

Product Details anti-MYD88 Antibody Target Details MYD88 Application Details Handling References for anti-MYD88 antibody (ABIN736881) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 240-290) antibody (ABIN736881) Formalin-fixed and paraffin embedded mouse lung tissue labeled with Anti-MyD88 Polycl...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 240-290) antibody (ABIN736881) Formalin-fixed and paraffin embedded mouse lung tissue labeled with Anti-MyD88 Polycl...