anti-Mouse (Murine) NFKBIA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended NFKBIA Antibody (supplied by: Log in to see )

Antigen
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antibodies
  • AI462015
  • Nfkbi
  • IKBA
  • MAD-3
  • NFKBI
  • ECI-6/IKBA
  • RL/IF-1
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • NFKBIA
  • LOC100220015
  • LOC100357341
  • Nfkbia
Epitope
AA 5-34
73
53
52
40
25
23
22
21
18
15
14
14
14
12
5
5
5
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
508
262
215
49
40
29
19
11
2
2
2
1
1
Host
Rabbit
349
166
6
Clonality
Polyclonal
Conjugate
This NFKBIA antibody is un-conjugated
19
15
14
12
9
8
6
6
5
5
5
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
3
3
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
395
182
178
88
88
85
68
39
34
19
9
6
5
4
3
3
2
2
1
1
1
1
1
Options
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Catalog No. ABIN674454
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.569733 ABIN252471 CyTOF FACS ICC IF IHC IHC (p) IP SimWes WB Mouse IgG1 kappa AA 32-291 Log in to see 6A920 33
11.569733 ABIN314166 ICC IF IHC (p) IHC WB Rabbit pSer32, pSer36 Log in to see Polyclonal 5
11.569733 ABIN498722 IHC (p) Rabbit pTyr42 Log in to see Polyclonal
11.569733 ABIN498601 IF IHC (p) WB Rabbit Log in to see Polyclonal
11.569733 ABIN218609 IF IHC (p) IP ELISA WB Rabbit C-Term Log in to see Polyclonal
11.569733 ABIN4324167 IHC IHC (p) WB Rabbit pTyr42 Log in to see Polyclonal
1 ABIN741360 IF (p) IHC (p) WB Rabbit IgG pSer32 Log in to see Polyclonal 1
1 ABIN3043889 IHC (p) WB Rabbit IgG AA 3-112 Log in to see Polyclonal
1 ABIN710696 IF (p) IHC (p) WB Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal 6
1 ABIN197304 IF IHC (p) WB Rabbit Ser32, Ser36 Log in to see Polyclonal 5
1 ABIN196874 IF IHC (p) WB Rabbit pSer32, pSer36 Log in to see Polyclonal 5
1 ABIN197390 IHC (p) WB Rabbit Tyr42 Log in to see Polyclonal 5
1 ABIN218341 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN214154 IF IHC (p) WB Rabbit IgG pSer32 Log in to see Polyclonal
1 ABIN2856763 ICC IF IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN2888443 IHC (p) ELISA Rabbit IgG pTyr42 Log in to see Polyclonal
1 ABIN265483 EIA IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN302954 IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN302978 IHC (p) IP WB Rabbit IgG Log in to see Polyclonal
1 ABIN318052 IHC (p) WB Rabbit pSer32, pSer36 Log in to see Polyclonal

General

Antigen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antibodies
Epitope AA 5-34
(73), (53), (52), (40), (25), (23), (22), (21), (18), (15), (14), (14), (14), (12), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(508), (262), (215), (49), (40), (29), (19), (11), (2), (2), (2), (1), (1)
Host Rabbit
(349), (166), (6)
Clonality
Polyclonal
Conjugate This NFKBIA antibody is un-conjugated
(19), (15), (14), (12), (9), (8), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(395), (182), (178), (88), (88), (85), (68), (39), (34), (19), (9), (6), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 10 references available
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Product Details anti-NFKBIA Antibody

Target Details NFKBIA Application Details Handling ProductDetails: References for anti-NFKBIA antibody (ABIN674454) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse IKB alpha
Isotype IgG

Target Details NFKBIA

Product Details anti-NFKBIA Antibody Application Details Handling ProductDetails: References for anti-NFKBIA antibody (ABIN674454) Images back to top
Antigen
Alternative Name Nfkbia/Ikb alpha (NFKBIA Antibody Abstract)
Background

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Subcellular location: Cytoplasm, Nucleus

Synonyms: Nfkbi, AI46215, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Nfkbia, Ikba

Gene ID 18035
UniProt Q9Z1E3
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades

Application Details

Product Details anti-NFKBIA Antibody Target Details NFKBIA Handling ProductDetails: References for anti-NFKBIA antibody (ABIN674454) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details ProductDetails: References for anti-NFKBIA antibody (ABIN674454) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-NFKBIA antibody (ABIN674454)

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details Handling Images back to top
Product cited in:

Gao, Guo, Wang, Lin, Yu, Sheng, Wu, Gong: "Indirubin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice through the inhibition of inflammation and the induction of Foxp3-expressing regulatory T cells." in: Acta histochemica, Vol. 118, Issue 6, pp. 606-14, 2016

Zhao, Zheng, Hu, Shen, Li: "Betulin attenuates kidney injury in septic rats through inhibiting TLR4/NF-κB signaling pathway." in: Life sciences, Vol. 144, pp. 185-93, 2016

Li, Zhang, Qi, Zhang, Yi, Li, Zhang: "Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-кB." in: The journal of headache and pain, Vol. 17, pp. 49, 2016

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Yan, Wu, Li, Meng, Dai, Zheng, Fu: "Cyanidin-3-O-glucoside Induces Apoptosis and Inhibits Migration of Tumor Necrosis Factor-?-Treated Rat Aortic Smooth Muscle Cells." in: Cardiovascular toxicology, 2015

Ma, Liu, Wang, Liu, Chen, Valle, Zuo, Xia, Liu: "Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals." in: ACS nano, Vol. 9, Issue 10, pp. 10498-515, 2015

Yan, Wu, Li, Meng, Dai, Zheng, Fu: "Cyanidin-3-O-glucoside attenuates acute lung injury in sepsis rats." in: The Journal of surgical research, Vol. 199, Issue 2, pp. 592-600, 2015

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, 2015

Yang, Wang, Zhang, Yang, Lu, Zhang, Li, Zhang, Li: "Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-?B signaling pathway in isoproterenol-induced myocardial hypertrophy." in: Journal of ethnopharmacology, Vol. 150, Issue 3, pp. 1062-70, 2014

Jiang, Tian, Fu, Zhu, Hou: "Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury." in: European journal of pharmacology, Vol. 640, Issue 1-3, pp. 75-81, 2010

Images

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details Handling ProductDetails: References for anti-NFKBIA antibody (ABIN674454) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 5-34) antibody (ABIN674454) Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-NFKBIA/IKB a...
Western Blotting (WB) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 5-34) antibody (ABIN674454) Lane 1: Mouse Spleen lysates probed with NFKBIA/IKB alpha Polyclonal Antibody, Unconj...