anti-Rat (Rattus) NFKBIA antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended NFKBIA Antibody (supplied by: Log in to see )

Antigen
Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antibodies
  • AI462015
  • Nfkbi
  • IKBA
  • MAD-3
  • NFKBI
  • ECI-6/IKBA
  • RL/IF-1
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • NFKBIA
  • LOC100220015
  • LOC100357341
  • Nfkbia
Epitope
pSer32
72
53
52
40
25
23
22
21
18
15
15
14
14
12
5
5
5
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
508
262
215
49
40
29
19
11
2
2
2
1
1
Host
Rabbit
349
166
6
Clonality
Polyclonal
Conjugate
This NFKBIA antibody is un-conjugated
19
15
14
12
9
8
6
6
5
5
5
5
5
5
5
5
5
5
5
3
3
3
3
3
3
3
3
3
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
395
182
178
88
88
85
68
39
34
19
9
6
5
4
3
3
2
2
1
1
1
1
1
Options
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Catalog No. ABIN741360
$ 329.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN710696 IF (p) IHC (p) WB Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal 6
1 ABIN674454 IF (p) IHC (p) WB Rabbit IgG AA 5-34 Log in to see Polyclonal 10
1 ABIN2804633 IF (p) Alexa Fluor 594 Rabbit IgG AA 5-34 Log in to see Polyclonal
1 ABIN2804632 IF (p) Alexa Fluor 594 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN710699 IF (p) Cy3 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN710700 IF (p) Cy5 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN710701 IF (p) Cy5.5 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN710702 IF (p) Cy7 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN710703 IF (p) FITC Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN674461 IF (p) FITC Rabbit IgG AA 5-34 Log in to see Polyclonal
1 ABIN674457 IF (p) Cy3 Rabbit IgG AA 5-34 Log in to see Polyclonal
1 ABIN674458 IF (p) Cy5 Rabbit IgG AA 5-34 Log in to see Polyclonal
1 ABIN674459 IF (p) Cy5.5 Rabbit IgG AA 5-34 Log in to see Polyclonal
1 ABIN674460 IF (p) Cy7 Rabbit IgG AA 5-34 Log in to see Polyclonal
1 ABIN879414 IF (p) Alexa Fluor 488 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN879415 IF (p) Alexa Fluor 647 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN879417 IF (p) Alexa Fluor 350 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN879418 IF (p) Alexa Fluor 555 Rabbit IgG AA 295-310, pTyr305 Log in to see Polyclonal
1 ABIN908224 IF (p) Alexa Fluor 488 Rabbit IgG AA 5-34 Log in to see Polyclonal
1 ABIN908223 IF (p) Alexa Fluor 350 Rabbit IgG AA 5-34 Log in to see Polyclonal

General

Antigen Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) Antibodies
Epitope pSer32
(72), (53), (52), (40), (25), (23), (22), (21), (18), (15), (15), (14), (14), (12), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(508), (262), (215), (49), (40), (29), (19), (11), (2), (2), (2), (1), (1)
Host Rabbit
(349), (166), (6)
Clonality
Polyclonal
Conjugate This NFKBIA antibody is un-conjugated
(19), (15), (14), (12), (9), (8), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(395), (182), (178), (88), (88), (85), (68), (39), (34), (19), (9), (6), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-NFKBIA Antibody

Target Details NFKBIA Application Details Handling ProductDetails: References for anti-NFKBIA antibody (ABIN741360) Images
Specificity These phosphorylation sites are homologous among the species listed.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Ser32/36
Isotype IgG

Target Details NFKBIA

Product Details anti-NFKBIA Antibody Application Details Handling ProductDetails: References for anti-NFKBIA antibody (ABIN741360) Images back to top
Antigen
Alternative Name Nfkbia (NFKBIA Antibody Abstract)
Background

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Subcellular location: Cytoplasm, Nucleus

Synonyms: IKBA, MAD-3, NFKBI, NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, MAD3

Gene ID 4792
UniProt P25963
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades

Application Details

Product Details anti-NFKBIA Antibody Target Details NFKBIA Handling ProductDetails: References for anti-NFKBIA antibody (ABIN741360) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details ProductDetails: References for anti-NFKBIA antibody (ABIN741360) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-NFKBIA antibody (ABIN741360)

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details Handling Images back to top
Product cited in:

Fu, Shi, Song, Xia, Su, Liu, Song, Song: "Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling." in: Environmental toxicology and pharmacology, Vol. 41, pp. 241-50, 2016

Images

Product Details anti-NFKBIA Antibody Target Details NFKBIA Application Details Handling ProductDetails: References for anti-NFKBIA antibody (ABIN741360) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (pSer32) antibody (ABIN741360) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-phospho-N...