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|Antigen||Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Antibodies|
|Epitope||AA 134-285 Alternatives|
|Conjugate||This TNFSF13B antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-TNFSF13B AntibodyTarget Details TNFSF13B Application Details Handling References for anti-TNFSF13B antibody (ABIN263920) Images
|Specificity||This antibody detects Human BLyS. Other species not tested.|
|Characteristics||Synonyms: TNFSF13B, BLYS, TALL1, TNFSF20, ZTNF4, Tumor necrosis factor ligand superfamily member13B, TNF- and APOL-related leukocyte expressed ligand 1, B lymphocyte stimulator, Bcell-activating factor, BAFF, Dendritic cell-derived TNF-like molecule|
|Purification||Protein-G affinity chromatography|
|Immunogen||Recombinant human BLyS (134-285aa) purified from E. coli|
Target Details TNFSF13BProduct Details anti-TNFSF13B Antibody Application Details Handling References for anti-TNFSF13B antibody (ABIN263920) Images back to top
|Alternative Name||CD257 / BAFF (TNFSF13B Antibody Abstract)|
|Background||B lymphocyte stimulator (BLyS),a member of the tumor necrosis factor (TNF) superfamily of cytokines, induces B-cell proliferation and immunoglobulin secretion and is a key regulator of peripheral B-cell populations in vivo.. BLyS is made by immune-cells called monocytes and macrophages. When monocytes and macrophages are activated, BLyS is released and binds to a receptor found only on B cells.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4|
|Pathways||NF-kappaB Signaling, Production of Molecular Mediator of Immune Response|
Application DetailsProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Handling References for anti-TNFSF13B antibody (ABIN263920) Images back to top
ELISA. Western blot (1: 500 approx. 1: 1,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details References for anti-TNFSF13B antibody (ABIN263920) Images back to top
|Buffer||PBS ( pH 7.4), 0.09 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C/-20 °C|
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.
|Expiry Date||12 months|
References for anti-TNFSF13B antibody (ABIN263920)Product Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details Handling Images back to top
Michaud, Daugherty, Berndt, Platz, Yeager, Crawford, Hsing, Huang, Hayes: "Genetic polymorphisms of interleukin-1B (IL-1B), IL-6, IL-8, and IL-10 and risk of prostate cancer." in: Cancer research, Vol. 66, Issue 8, pp. 4525-30, 2006
Allan, Tyrrell, Rothwell: "Interleukin-1 and neuronal injury." in: Nature reviews. Immunology, Vol. 5, Issue 8, pp. 629-40, 2005
ImagesProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details Handling References for anti-TNFSF13B antibody (ABIN263920) back to top