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|Application / Reactivity||Human|
|Blocking Antibody (Inhibition)||3 Antibodies|
|ELISA (Capture)||1 Antibodies|
|Enzyme Immunoassay (EIA)||9 Antibodies|
|Flow Cytometry (FACS)||60 Antibodies|
|Functional Studies (Func)||9 Antibodies|
|Immunochromatography (IC)||3 Antibodies|
|Immunocytochemistry (ICC)||13 Antibodies|
|Immunofluorescence (IF)||2 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||11 Antibodies|
|Immunohistochemistry (IHC)||42 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||25 Antibodies|
|Immunoprecipitation (IP)||19 Antibodies|
|Intracellular Flow Cytometry (ICFC)||2 Antibodies|
|Neutralization (Neut)||2 Antibodies|
|Western Blotting (WB)||158 Antibodies|
|Antigen||Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) Antibodies|
|Conjugate||This TNFSF13B antibody is conjugated to PE Alternatives|
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
|5 references available|
|Supplier||Log in to see|
Product Details anti-TNFSF13B AntibodyTarget Details TNFSF13B Application Details Handling References for anti-TNFSF13B Antibody (ABIN2663232) Images
|Characteristics||The T7-241 antibody recognizes human BAFF also known as B cell activating factor, tumor necrosis factor ligand superfamily 13B, B lymphocyte stimulator (BLYS), TNF and APOL-related leukocyte expressed ligand 1 (TALL1), and TNF homolog that activates apoptosis, NF-κB, and JNK (THANK). BAFF is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. BAFF can be proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homotrimers. The predicted molecular weight of a BAFF monomer is approximately 31 kD. BAFF is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-γ and downregulated by PMA/ionomycin treatment. The T7-241 antibody has been shown to be useful for flow cytometry and ELISA. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). The T7-241 antibody has been shown to be useful for flow cytometry and ELISA.|
|Purification||The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.|
Target Details TNFSF13BProduct Details anti-TNFSF13B Antibody Application Details Handling References for anti-TNFSF13B Antibody (ABIN2663232) Images back to top
|Alternative Name||CD257 (TNFSF13B Antibody Abstract)|
Application DetailsProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Handling References for anti-TNFSF13B Antibody (ABIN2663232) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details References for anti-TNFSF13B Antibody (ABIN2663232) Images back to top
|Buffer||Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Protect from prolonged exposure to light. Do not freeze.|
|Storage Comment||The antibody solution should be stored undiluted between 2°C and 8°C.|
References for anti-TNFSF13B Antibody (ABIN2663232)Product Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details Handling Images back to top
Oren, Li, Volovik et al.: "Structural basis of BLyS receptor recognition." in: Nature structural biology, Vol. 9, Issue 4, pp. 288-92, 2002 (PubMed).
Yu, Boone, Delaney et al.: "APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity." in: Nature immunology, Vol. 1, Issue 3, pp. 252-6, 2001 (PubMed).
Moore, Belvedere, Orr et al.: "BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator." in: Science (New York, N.Y.), Vol. 285, Issue 5425, pp. 260-3, 1999 (PubMed).
Schneider, MacKay, Steiner et al.: "BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth." in: The Journal of experimental medicine, Vol. 189, Issue 11, pp. 1747-56, 1999 (PubMed).
Shu, Hu, Johnson: "TALL-1 is a novel member of the TNF family that is down-regulated by mitogens." in: Journal of leukocyte biology, Vol. 65, Issue 5, pp. 680-3, 1999 (PubMed).
ImagesProduct Details anti-TNFSF13B Antibody Target Details TNFSF13B Application Details Handling References for anti-TNFSF13B Antibody (ABIN2663232) back to top