anti-Human TRAF2 antibody for Enzyme Immunoassay

Recommended TRAF2 Antibody (supplied by: Log in to see )

Antigen
TNF Receptor-Associated Factor 2 (TRAF2) Antibodies
  • MGC:45012
  • TRAP
  • TRAP3
  • TANK
  • AI325259
  • TNF-receptor-associated factor 2
  • conjugal transfer protein TraF
  • TNF receptor-associated factor 2
  • Tnf receptor-associated factor 2
  • Traf2
  • traF2
  • TRAF2
Epitope
Internal Region
42
15
13
11
10
7
7
5
4
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
193
66
56
6
3
3
2
2
1
1
Host
Rabbit
112
66
21
1
Clonality
Polyclonal
Conjugate
This TRAF2 antibody is un-conjugated
7
7
6
5
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
175
85
71
57
30
28
18
13
6
5
3
3
3
2
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN5551848
$ 411.18
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5610979 EIA WB Rabbit Ig Fraction C-Term Log in to see Polyclonal
1 ABIN5555368 EIA IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal
1 ABIN5555367 EIA IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal

General

Antigen TNF Receptor-Associated Factor 2 (TRAF2) Antibodies
Epitope Internal Region
(42), (15), (13), (11), (10), (7), (7), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(193), (66), (56), (6), (3), (3), (2), (2), (1), (1)
Host Rabbit
(112), (66), (21), (1)
Clonality
Polyclonal
Conjugate This TRAF2 antibody is un-conjugated
(7), (7), (6), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(175), (85), (71), (57), (30), (28), (18), (13), (6), (5), (3), (3), (3), (2)
Supplier Log in to see

Product Details anti-TRAF2 Antibody

Target Details TRAF2 Application Details Handling Images
Specificity This antibody is directed against TRAF2 protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Characteristics Concentration: 0.93 mg/mL (by UV absorbance at 280 nm)
Purification Affinity chromatography
Immunogen Synthetic peptide corresponding to an internal region human TRAF2
Isotype IgG

Target Details TRAF2

Product Details anti-TRAF2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TRAF2 / TRAP3 (TRAF2 Antibody Abstract)
Background TRAF2, or Tumor Necrosis factor (TNF) Receptor-Associated Factor 2, is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Association to the receptor is also mediated by the interaction with TRADD. TRAF2 mediates activation of NF-kappa-B and MAPK8/JNK and is involved in apoptosis. TRAF2 forms a heterodimeric complex with TRAF1, which then recruits the inhibitor-of-apoptosis proteins (IAPs), apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 for the inhibition of caspase activation. In this way it functions as a mediator of the anti-apoptotic signals from TNF receptors. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. TRAF2 may be involved in IL-15 signaling. Multiple alternatively spliced transcript variants exist, but the biological validity of only one transcript has been determined.Synonyms: TNF receptor-associated factor 2, Tumor necrosis factor type 2 receptor-associated protein 3
Gene ID 7186
NCBI Accession NP_066961
UniProt Q12933
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded protein response

Application Details

Product Details anti-TRAF2 Antibody Target Details TRAF2 Handling Images back to top
Application Notes ELISA: 1/60,000 - 1/250,000. Western Blot: 1 μg/m. Immunohistochemistry. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TRAF2 Antibody Target Details TRAF2 Application Details Images back to top
Concentration 0.93 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C