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anti-Human TRAF2 antibody for Immunohistochemistry (Frozen Sections)

Recommended TRAF2 Antibody (supplied by: Log in to see )

Antigen
TNF Receptor-Associated Factor 2 (TRAF2) Antibodies
  • AI325259
  • MGC:45012
  • TANK
  • TRAP
  • TRAP3
Epitope
Internal Region
45
15
13
10
9
9
7
4
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
153
53
44
5
2
1
1
Host
Rabbit
101
39
18
1
Clonality
Polyclonal
Conjugate
This TRAF2 antibody is un-conjugated
6
6
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
137
70
55
25
21
19
11
8
4
4
3
3
Supplier
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Catalog No. ABIN401470
$ 253.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008888643 ABIN401469 EIA IHC (fro) IP WB Rabbit IgG Internal Region Log in to see Polyclonal 1
0.0008888643 ABIN957235 IHC (fro) IHC (p) IP WB Rabbit AA 87-106 Log in to see Polyclonal
0.0008888643 ABIN957236 IHC (fro) IHC (p) IP WB Rabbit AA 6-31 Log in to see Polyclonal

Top referenced anti-TRAF2 antibody for Immunohistochemistry (Frozen Sections)

Similar anti-TRAF2 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 17 Antibodies 70 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies 5 Antibodies
Immunocytochemistry (ICC) 3 Antibodies 9 Antibodies
Immunofluorescence (IF) 6 Antibodies 22 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 22 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 10 Antibodies
Immunoprecipitation (IP) 11 Antibodies
Western Blotting (WB) 41 Antibodies
Flow Cytometry (FACS) 1 Antibodies
Immunochromatography (IC) 3 Antibodies

General

Antigen TNF Receptor-Associated Factor 2 (TRAF2) Antibodies
Epitope Internal Region
(45), (15), (13), (10), (9), (9), (7), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(153), (53), (44), (5), (2), (1), (1)
Host Rabbit
(101), (39), (18), (1)
Clonality
Polyclonal
Conjugate This TRAF2 antibody is un-conjugated
(6), (6), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(137), (70), (55), (25), (21), (19), (11), (8), (4), (4), (3), (3)
Pubmed 1 reference available
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Product Details anti-TRAF2 Antibody

Target Details TRAF2 Application Details Handling References for anti-TRAF2 Antibody (ABIN401470) Images
Specificity This antibody is directed against TRAF2 protein.
Cross-Reactivity (Details) Species reactivity (expected):Mouse.
Species reactivity (tested):Human.
Purification Affinity chromatography
Immunogen Synthetic peptide corresponding to an internal region human TRAF2
Isotype IgG

Target Details TRAF2

Product Details anti-TRAF2 Antibody Application Details Handling References for anti-TRAF2 Antibody (ABIN401470) Images back to top
Antigen
Alternative Name TRAF2 / TRAP3 (TRAF2 Antibody Abstract)
Background TRAF2, or Tumor Necrosis factor (TNF) Receptor-Associated Factor 2, is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Association to the receptor is also mediated by the interaction with TRADD. TRAF2 mediates activation of NF-kappa-B and MAPK8/JNK and is involved in apoptosis. TRAF2 forms a heterodimeric complex with TRAF1, which then recruits the inhibitor-of-apoptosis proteins (IAPs), apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 for the inhibition of caspase activation. In this way it functions as a mediator of the anti-apoptotic signals from TNF receptors. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. TRAF2 may be involved in IL-15 signaling. Multiple alternatively spliced transcript variants exist, but the biological validity of only one transcript has been determined.Synonyms: TNF receptor-associated factor 2, Tumor necrosis factor type 2 receptor-associated protein 3
Gene ID 7186
NCBI Accession NP_066961
UniProt Q12933
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-TRAF2 Antibody Target Details TRAF2 Handling References for anti-TRAF2 Antibody (ABIN401470) Images back to top
Application Notes ELISA: 1/60,000 - 1/250,000. Western Blot: 1 μg/m. Immunohistochemistry. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TRAF2 Antibody Target Details TRAF2 Application Details References for anti-TRAF2 Antibody (ABIN401470) Images back to top
Format Liquid
Concentration 0.93 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C

References for anti-TRAF2 Antibody (ABIN401470)

Product Details anti-TRAF2 Antibody Target Details TRAF2 Application Details Handling Images back to top
Background publications

Li, Wang, Berman, Zhang, Dorf: "RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling." in: Molecular cell, Vol. 24, Issue 4, pp. 497-509, 2006

Images

Product Details anti-TRAF2 Antibody Target Details TRAF2 Application Details Handling References for anti-TRAF2 Antibody (ABIN401470) back to top
Supplier Images
 image for anti-TRAF2 antibody (TNF Receptor-Associated Factor 2) (Internal Region) (ABIN401470) anti-TNF Receptor-Associated Factor 2 (TRAF2) (Internal Region) antibody