anti-Mouse (Murine) TRAF6 antibody for Enzyme Immunoassay

Recommended TRAF6 Antibody (supplied by: Log in to see )

Antigen
TNF Receptor-Associated Factor 6 (TRAF6) Antibodies
  • rnf85
  • traf6
  • xtraf6
  • CG10961
  • DTRAF2
  • Dmel\\CG10961
  • TRAF
  • TRAF2
  • TRAF6
  • Traf2
  • dTRAF2
  • dTRAF6
  • dTraf2
  • dtraf2
  • GB10539
  • 2310003F17Rik
  • AI851288
  • C630032O20Rik
  • fi15f02
  • wu:fi15f02
  • zgc:63704
  • MGC:3310
  • RNF85
  • TNF receptor-associated factor 6, E3 ubiquitin protein ligase
  • TNF-receptor-associated factor 6
  • TNF receptor-associated factor 6
  • traf6-b
  • Traf6
  • TRAF6
  • traf6
Epitope
C-Term
24
20
19
11
11
5
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
156
83
71
10
8
6
5
3
3
1
1
Host
Rabbit
137
28
2
Clonality
Polyclonal
Conjugate
This TRAF6 antibody is un-conjugated
5
5
5
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
134
48
37
32
27
23
22
20
13
5
5
3
2
2
1
Supplier
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Catalog No. ABIN5555371
$ 375.38
Plus shipping costs $45.00

General

Antigen TNF Receptor-Associated Factor 6 (TRAF6) Antibodies
Epitope C-Term
(24), (20), (19), (11), (11), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(156), (83), (71), (10), (8), (6), (5), (3), (3), (1), (1)
Host Rabbit
(137), (28), (2)
Clonality
Polyclonal
Conjugate This TRAF6 antibody is un-conjugated
(5), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(134), (48), (37), (32), (27), (23), (22), (20), (13), (5), (5), (3), (2), (2), (1)
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Product Details anti-TRAF6 Antibody

Target Details TRAF6 Application Details Handling Images
Specificity This antibody detects TRAF6 / RNF85 at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Ion exchange chromatography
Immunogen TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C- terminus of human TRAF6.
Isotype IgG

Target Details TRAF6

Product Details anti-TRAF6 Antibody Application Details Handling Images back to top
Antigen
Alternative Name TRAF6 / RNF85 (TRAF6 Antibody Abstract)
Background Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-?B (1,2). TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families (3). TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands (4). It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) (5) or by other TLR adaptor molecules such as TRIF (6). Also, it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK (7).Synonyms: Interleukin-1 signal transducer, RING finger protein 85, TNF receptor-associated factor 6
Gene ID 7189
NCBI Accession NP_004611
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-TRAF6 Antibody Target Details TRAF6 Handling Images back to top
Application Notes ELISA. Western blot: 1 to 2 μg/mL. Immunflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-TRAF6 Antibody Target Details TRAF6 Application Details Images back to top
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.