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Browse our F2R (F2R) ELISA Kits

Full name:
Coagulation Factor II (thrombin) Receptor ELISA Kits (F2R)
On are 62 Coagulation Factor II (thrombin) Receptor (F2R) ELISA Kits from 10 different suppliers available. Additionally we are shipping F2R Antibodies (181) and F2R Proteins (5) and many more products for this protein. A total of 264 F2R products are currently listed.
AI482343, BXR, Cf2r, f2r-a, HTR, ONR1, PAR, Par-1, Par1, PAR2, PARq, PRR, PXR, SAR, SXR, ThrR, TR, TRGPC
list all ELISA KIts Gene Name GeneID UniProt
F2R 2149 P25116
F2R 14062 P30558
F2R 25439  

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Top referenced F2R ELISA Kits

  1. Human F2R ELISA Kit for Sandwich ELISA - ABIN418624 : Karabulut, Ak?it, Tas, Ciftci, Aydiner, Yildiz, Keskin, Eralp, Yasasever, Vatansever, Disci, Saip: Is there any diagnostic value of serum protease-activated receptor-1 (PAR1) levels on determination of epithelial ovarian carcinoma? in Tumour biology 2014 (PubMed)

More ELISA Kits for F2R Interaction Partners

Human Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. Extracellular granzyme K (show GZMK ELISA Kits) mediates endothelial activation through the cleavage of PAR-1 (show MARK2 ELISA Kits).

  2. Pregnane X receptor interacts with liver X receptor to regulate expression of SMPDL3A in primary hepatocytes.

  3. 66034T/C polymorphism of the human pregnane X receptor (show NR1I2 ELISA Kits) (hPXR) is potential risk factor for drug-resistant epilepsy.

  4. The data suggest that some of the natural PXR (show NR1I2 ELISA Kits) variants may have adverse physiological consequences owing to its influence on the expression levels and functional output of drug-metabolizing enzymes and transporters.

  5. miR (show MLXIP ELISA Kits)-30c-1-3p was shown to alter the expression of CYP3A4 (show CYP3A4 ELISA Kits), a prototypical target gene of PXR (show NR1I2 ELISA Kits).

  6. The nuclear receptor PXR (show NR1I2 ELISA Kits) regulates hepatic energy metabolism. (Review)

  7. Novel functions of PXR (show NR1I2 ELISA Kits) in cardiometabolic disease development have been described. (Review)

  8. Acetylation of lysine 109 modulates PXR (show NR1I2 ELISA Kits) DNA binding and transcriptional activity; PXR (show NR1I2 ELISA Kits) acetylation status and transcriptional activity are modulated by E1A binding protein (p300 (show EP300 ELISA Kits)) and SIRT1 (show SIRT1 ELISA Kits).

  9. Genome-wide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR (show NR1I2 ELISA Kits) and PPARalpha (show PPARA ELISA Kits) in primary human hepatocytes has been presented.

  10. PXR (show NR1I2 ELISA Kits) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK (show MYLK ELISA Kits) expression and JNK1 (show MAPK8 ELISA Kits)/2 activation

Mouse (Murine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. thrombin (show F2 ELISA Kits)/PAR-1 (show MARK2 ELISA Kits) interaction regulated MCP-1 (show CPT1B ELISA Kits), TF, MCSF (show CSF1 ELISA Kits) and IL-6 (show IL6 ELISA Kits) production.

  2. Thrombin (show F2 ELISA Kits) upregulates LCN2 (show LCN2 ELISA Kits) through protease-activated receptor-1 activation and causes brain damage.

  3. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (show MMP1 ELISA Kits)/protease-activated receptor-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  4. Data indicate an involvement of protease-activated receptor-1 in the neuroinflammation mediated by Eomes (show EOMES ELISA Kits)(+) CD4 (show CD4 ELISA Kits)(+) T cells.

  5. Bladder PAR (show AFG3L2 ELISA Kits) activation elicits urothelial MIF (show MIF ELISA Kits) release and urothelial MIF (show MIF ELISA Kits) receptor signaling at least partly through CXCR4 (show CXCR4 ELISA Kits) to result in abdominal hypersensitivity without overt bladder inflammation

  6. Data suggest that the pro-fibrotic effects of protease-activated receptor PAR-1 (show MARK2 ELISA Kits) require the presence of protease-activated receptor PAR-2 (show F2RL1 ELISA Kits).

  7. Thrombin (show F2 ELISA Kits)-PAR1 signaling, via nitric oxide and EPCR (show PROCR ELISA Kits), promotes hematopoietic stem cell (HSC (show FUT1 ELISA Kits)) mobilization. aPC (show APC ELISA Kits)-EPCR (show PROCR ELISA Kits)-PAR1 signaling promotes HSC (show FUT1 ELISA Kits) retention in bone marrow.

  8. Colonic adenocarcinoma growth was reduced in PAR-1 (show MARK2 ELISA Kits)-deficient mice. Stromal cell-associated PAR-1 (show MARK2 ELISA Kits) as one thrombin (show F2 ELISA Kits) target important for tumor outgrowth.

  9. Interference with the thrombin (show F2 ELISA Kits)-PAR1 system does not reduce the adverse effects of blood on germinal cells of the immature mouse brain.

  10. Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis

Cow (Bovine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. MMP-1 (show MMP1 ELISA Kits) promotes VEGFR2 (show KDR ELISA Kits) expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB (show NFKB1 ELISA Kits)

  2. PAR1 and PAR2 (show F2RL1 ELISA Kits) regulate endothelial NO synthase (show NOS ELISA Kits) phosphorylation and activity through G(12/13) and G(q), delineating the signaling pathways by which the proteases act on protease-activated receptors to modulate endothelial functions.

Pig (Porcine) Coagulation Factor II (thrombin) Receptor (F2R) interaction partners

  1. Thrombin (show F2 ELISA Kits) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA (show RHOA ELISA Kits), and myocardin (show MYOCD ELISA Kits).

  2. Thrombin (show F2 ELISA Kits) induces a sustained contraction in the normal pulmonary artery, by activating PAR(1) and thereby increasing the sensitivity of the myofilament to Ca(2 (show CA2 ELISA Kits)+).

F2R Antigen Profile

Antigen Summary

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

Alternative names and synonyms associated with F2R

  • coagulation factor 2 (thrombin) receptor (f2r) Elisa Kit
  • coagulation factor II (thrombin) receptor (F2R) Elisa Kit
  • coagulation factor II (thrombin) receptor (F2r) Elisa Kit
  • nuclear receptor subfamily 1, group I, member 2 (NR1I2) Elisa Kit
  • AI482343 Elisa Kit
  • BXR Elisa Kit
  • Cf2r Elisa Kit
  • f2r-a Elisa Kit
  • HTR Elisa Kit
  • ONR1 Elisa Kit
  • PAR Elisa Kit
  • Par-1 Elisa Kit
  • Par1 Elisa Kit
  • PAR2 Elisa Kit
  • PARq Elisa Kit
  • PRR Elisa Kit
  • PXR Elisa Kit
  • SAR Elisa Kit
  • SXR Elisa Kit
  • ThrR Elisa Kit
  • TR Elisa Kit
  • TRGPC Elisa Kit

Protein level used designations for F2R

PAR-1 , coagulation factor II (thrombin) receptor , coagulation factor II receptor , proteinase-activated receptor 1 , thrombin receptor , protease-activated receptor 1 , Thrombin receptor , protease-activated receptor-1 , nuclear receptor subfamily 1 group I member 2 , orphan nuclear receptor PAR1 , orphan nuclear receptor PXR , pregnane X nuclear receptor variant 2 , pregnane X receptor , steroid and xenobiotic receptor

378526 Xenopus laevis
2149 Homo sapiens
14062 Mus musculus
25439 Rattus norvegicus
526585 Bos taurus
100521609 Sus scrofa
8856 Homo sapiens
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