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Browse our RP2 (RP2) ELISA Kits

Full name:
Retinitis Pigmentosa 2 (X-Linked Recessive) ELISA Kits (RP2)
On www.antibodies-online.com are 0 Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2) ELISA Kits from different suppliers available. Additionally we are shipping RP2 Proteins (1) and many more products for this protein. A total of 2 RP2 products are currently listed.
Synonyms:
AI662636, DELXp11.3, NM23-H10, NME10, RGD1565124, Rp2, Rp2h, TBCCD2, wu:fj10e02, wu:fm72d05, XRP2, zfrp2, zgc:55632
list all ELISA KIts Gene Name GeneID UniProt
Rat RP2 RP2 367714  
Human RP2 RP2 6102 O75695
Mouse RP2 RP2 19889 Q9EPK2

Show all synonyms

More ELISA Kits for RP2 Interaction Partners

Zebrafish Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2) interaction partners

  1. study also reveals a role of the C-terminal domain of RP2 in maintaining the overall protein stability.

  2. maternal rp2 mRNA is essential for successful embryonic development and thus contributes to egg developmental competence

  3. Knockout of RP2 decreases GRK1 (show GRK1 ELISA Kits) and rod transducin (show GNAT1 ELISA Kits) subunits and leads to photoreceptor degeneration in zebrafish

  4. Results suggest that RP2 plays a key role in photoreceptor development and maintenance in zebrafish

  5. Zebrafish RP2 is widely expressed throughout development. ZFRP2 knockdown caused retinal degeneration in zebrafish.

Human Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2) interaction partners

  1. study also reveals a role of the C-terminal domain of RP2 in maintaining the overall protein stability.

  2. Three XLRP families (RP-001, RP-002, and RP-003), composed of 13 individuals, were reported in this study, and 2 different mutations were detcted We found 3 genetic variants: a novel mutation c.1591G>T in exon 14 and a novel polymorphism c.1105C>T in exon 10, resulting in p.Glu531* and p.Arg369Cys of RPGR (show RPGR ELISA Kits) gene, respectively, and one already known mutation c.413A>G in exon 2, resulting in a p.Glu138Gly of RP2 gene

  3. We identified a novel causative mutation in RP2 from a single proband's exome sequence data analysis. This study highlights the effectiveness of the whole-exome sequencing in the genetic diagnosis of X-linked retinitis pigmentosa, over the conventional sequencing methods.

  4. Three mutations were identified in the ORF15 (show RPGR ELISA Kits) exon of RPGR (show RPGR ELISA Kits). No RP2 mutations were found among the examined families. Mutation screening of RP patients is essential to understand the mechanism behind this disease and develop treatments

  5. seven out of 27 families, displaying mutations in the ABCA4 (show ABCA4 ELISA Kits), RP1 (show STK19 ELISA Kits), RP2 and USH2A (show USH2A ELISA Kits) genes, could be genetically or clinically reclassified. These results demonstrate the potential of our panel-based NGS strategy in RP diagnosis

  6. The ability of the restored RP2 protein (show P2RX1 ELISA Kits) level to reverse the observed cellular phenotypes in cells lacking RP2 indicates that translational read-through could be clinically beneficial for patients.

  7. ellipsometric measurements of naRP2 demonstrated that its particular affinity for saturated phospholipids can be explained by its larger extent of insertion in this phospholipid monolayer compared to that in polyunsaturated phospholipid monolayers.

  8. The methylation state of CpG sites close to the RP2 core promoter (GAAA)n repeat serves as a proxy measurement of X-chromosome inactivation in human and non-human primates.

  9. A novel frameshift mutation in RP2 was detected. This mutation was located in exon 2 of the RP2 gene: a nucleotide C was inserted at 111 (c.111insC, Fig. 1A), which caused a protein translation frameshift

  10. Direct sequencing of RPGR (show RPGR ELISA Kits) and RP2 allowed for identification of a disease-causing mutation in 21 families. Of these "adRP (show PLIN2 ELISA Kits)" families 19 had RPGR (show RPGR ELISA Kits) mutations, and two had RP2 mutations.

Mouse (Murine) Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2) interaction partners

  1. RP2 has a role in cone photoreceptor sensory cilium elongation in mice

  2. we first performed detailed characterization of the Rp2-knockout (Rp2-KO) mice and observed early-onset cone dysfunction

  3. Our studies suggest that RP2 contributes to the maintenance of photoreceptor function and that cone opsin (show RHO ELISA Kits) mislocalization represents an early step in XLRP caused by RP2 mutations.

  4. We propose that RP2 regulation of Arl3 is important for maintaining Golgi cohesion, facilitating the transport and docking of vesicles and thereby carrying proteins to the base of the photoreceptor connecting cilium for transport to the outer segment.

RP2 Antigen Profile

Antigen Summary

The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death

Alternative names and synonyms associated with RP2

  • retinitis pigmentosa 2 homolog (human) (Rp2) Elisa Kit
  • retinitis pigmentosa 2 (X-linked recessive) (RP2) Elisa Kit
  • XRP2 protein (Bm1_36735) Elisa Kit
  • XRP2-like protein (PITG_13367) Elisa Kit
  • XRP2 protein (LOAG_11813) Elisa Kit
  • XRP2 protein (LOC100338686) Elisa Kit
  • retinitis pigmentosa 2 (X-linked recessive) (rp2) Elisa Kit
  • retinitis pigmentosa 2 homolog (human) (Rp2h) Elisa Kit
  • AI662636 Elisa Kit
  • DELXp11.3 Elisa Kit
  • NM23-H10 Elisa Kit
  • NME10 Elisa Kit
  • RGD1565124 Elisa Kit
  • Rp2 Elisa Kit
  • Rp2h Elisa Kit
  • TBCCD2 Elisa Kit
  • wu:fj10e02 Elisa Kit
  • wu:fm72d05 Elisa Kit
  • XRP2 Elisa Kit
  • zfrp2 Elisa Kit
  • zgc:55632 Elisa Kit

Protein level used designations for RP2

protein XRP2 , retinitis pigmentosa 2 (X-linked recessive) , XRP2 protein , XRP2-like protein , protein XRP2-like , nme10 , retinitis pigmentosa 2 homolog

GENE ID SPECIES
367714 Rattus norvegicus
465596 Pan troglodytes
534054 Bos taurus
6102232 Brugia malayi
9474509 Phytophthora infestans T30-4
9949274 Loa loa
100338686 Oryctolagus cuniculus
100468530 Ailuropoda melanoleuca
406755 Danio rerio
491853 Canis lupus familiaris
711227 Macaca mulatta
100060484 Equus caballus
100380020 Xenopus (Silurana) tropicalis
100413670 Callithrix jacchus
100460005 Pongo abelii
100622983 Sus scrofa
6102 Homo sapiens
418675 Gallus gallus
379779 Xenopus laevis
19889 Mus musculus
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