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Browse our CD82 Proteins (CD82)

Full name:
CD82 Molecule Proteins (CD82)
On are 7 CD82 Molecule (CD82) Proteins from 4 different suppliers available. Additionally we are shipping CD82 Antibodies (142) and CD82 Kits (3) and many more products for this protein. A total of 162 CD82 products are currently listed.
4F9, AA682076, AL023070, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
list all proteins Gene Name GeneID UniProt
CD82 12521 P40237
CD82 3732 P27701
Rat CD82 CD82 83628  

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CD82 Proteins (CD82) by Origin

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Top referenced CD82 Proteins

  1. Human CD82 Protein expressed in Human Cells - ABIN2005160 : Tonoli, Barrett: CD82 metastasis suppressor gene: a potential target for new therapeutics? in Trends in molecular medicine 2005 (PubMed)

More Proteins for CD82 Interaction Partners

Mouse (Murine) CD82 Molecule (CD82) interaction partners

  1. The perturbation of CD82-ganglioside-CD44 (show CD44 Proteins) signaling attenuates pathological angiogenesis.

  2. Loss of Kai1 expression is associated with neoplasm metastasis.

  3. The synergistic effects of CD82 and GM3 (show GRM6 Proteins) or GM2 (show CYB5D2 Proteins)/GM3 (show GRM6 Proteins) ganglioside on EGFR (show EGFR Proteins) expression and phosphorylation and cMet activation are responsible for CD82 inhibition of EGF (show EGF Proteins)- and HGF (show HGF Proteins)-dependent cell motility and migration of Hepa1-6 cells.

  4. CD81 (show CD81 Proteins) promotes the microvillus formation and/or extension while tetraspanin CD82 inhibits these events. In addition, CD81 (show CD81 Proteins) enhances the outward bending of the plasma membrane while CD82 inhibits it.

  5. the CD82 tetraspanin is specifically recruited to pathogen-containing phagosomes prior to fusion with lysosomes.

  6. KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase

  7. Hypoxia-dependent induction of KAI1 was directly mediated by hypoxia-inducible factor-1alpha binding on the promoter, which subsequently caused increased recruitment of RNA polymerase II for transcriptional activation.

  8. An antibody to this protein that can specifically detect murine Kai1/CD82, should be useful in addressing the mechanism of action of Kai1 in metastatic suppression.

  9. gp78 (show AMFR Proteins) promotes sarcoma metastasis by targeting KAI1 for degradation

  10. The transgenic adenocarcinoma of mouse prostate model encompasses androgen depletion independent sublines with increased tumorigenicity and invasiveness. All showed downregulation in tumor suppressor, E-cadherin (show CDH1 Proteins), and metastatis suppressor, KAI-1.

Human CD82 Molecule (CD82) interaction partners

  1. Survivin (show BIRC5 Proteins), Bcl-2 (show BCL2 Proteins), and KAI1 are metastasis-related factors in cervical cancer. Overexpression of survivin (show BIRC5 Proteins) and Bcl-2 (show BCL2 Proteins), and low expression of KAI1 promotes cervical cancer progress and metastasis.

  2. KAI1 was able to suppress melanoma angiogenesis by downregulating IL-6 and VEGF expression.

  3. Loss of both KAI1 and p27 (show PAK2 Proteins) defines a subgroup of primary melanoma patients with poor prognosis.

  4. The expression of KAI1/CD82, CD44 (show CD44 Proteins), MMP7 (show MMP7 Proteins) and beta-catenin (show CTNNB1 Proteins) is related to tumor metastasis and prognosis in colorectal carcinoma.

  5. Serum-free media and hypoxia protected the MiaPaCa-2 cells from a KAI1-induced apoptosis and proliferation inhibition via autophagy induction.

  6. High KAI1 expression is associated with epithelial-mesenchymal transition in non-small cell lung cancer.

  7. CD82 regulated BCL2L12 (show BCL2L12 Proteins) expression via STAT5A (show STAT5A Proteins) and AKT (show AKT1 Proteins) signaling and stimulated proliferation and engrafting of leukemia cells.

  8. CD82 enhanced the expression of miR (show MLXIP Proteins)-203 and directly downregulated FZD2 (show FZD2 Proteins) expression, suppressing cancer metastasis/cell migration by inhibiting the Wnt (show WNT2 Proteins) signaling pathway.

  9. blockade of CD82 in leukemia cells lowered EZH2 (show EZH2 Proteins) expression via activation of p38 MAPK (show MAPK14 Proteins) signaling.

  10. KAI1-splice does not only counteract the tumor-suppressive actions of KAI1, but - beyond that - promotes alphavbeta3-mediated biological functions in favor of tumor progression and metastasis.

CD82 Protein Profile

Protein Summary

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with CD82

  • CD82 antigen (Cd82)
  • CD82 molecule (CD82)
  • Cd82 molecule (Cd82)
  • 4F9 protein
  • AA682076 protein
  • AL023070 protein
  • C33 protein
  • GR15 protein
  • IA4 protein
  • KAI1 protein
  • R2 protein
  • SAR2 protein
  • ST6 protein
  • TSPAN27 protein

Protein level used designations for CD82 Molecule Proteins (CD82)

C33 antigen , inducible membrane protein R2 , kangai 1 (suppression of tumorigenicity 6, prostate) , metastasis suppressor Kangai-1 homolog , CD82 antigen , kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) , metastasis suppressor Kangai-1 , tetraspanin-27 , tspan-27 , CD82 antigen (R2 leukocyte antigen antigen detected by monoclonal and antibody IA4)) , CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) , Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen , Kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) , kangai 1 (suppression of tumorigenicity 6), prostate

12521 Mus musculus
3732 Homo sapiens
83628 Rattus norvegicus
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