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Browse our CD82 Proteins (CD82)

Full name:
CD82 Molecule Proteins (CD82)
On www.antibodies-online.com are 10 CD82 Molecule (CD82) Proteins from 4 different suppliers available. Additionally we are shipping CD82 Antibodies (174) and CD82 Kits (4) and many more products for this protein. A total of 198 CD82 products are currently listed.
Synonyms:
4F9, AA682076, AL023070, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
list all proteins Gene Name GeneID UniProt
CD82 12521 P40237
CD82 3732 P27701
Rat CD82 CD82 83628  

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CD82 Proteins (CD82) by Origin

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Top referenced CD82 Proteins

  1. Human CD82 Protein expressed in Human Cells - ABIN2005160 : Tonoli, Barrett: CD82 metastasis suppressor gene: a potential target for new therapeutics? in Trends in molecular medicine 2005 (PubMed)

More Proteins for CD82 Interaction Partners

Mouse (Murine) CD82 Molecule (CD82) interaction partners

  1. The CD82 is a functional surface marker of long-term repopulating hematopoietic stem cells (LT-HSCs) that maintains quiescence through interaction with DARC (show DARC Proteins)-expressing macrophages in the bone marrow stem cell niche.

  2. The perturbation of CD82-ganglioside-CD44 (show CD44 Proteins) signaling attenuates pathological angiogenesis.

  3. Loss of Kai1 expression is associated with neoplasm metastasis.

  4. The synergistic effects of CD82 and GM3 (show GRM6 Proteins) or GM2 (show CYB5D2 Proteins)/GM3 (show GRM6 Proteins) ganglioside on EGFR (show EGFR Proteins) expression and phosphorylation and cMet activation are responsible for CD82 inhibition of EGF (show EGF Proteins)- and HGF (show HGF Proteins)-dependent cell motility and migration of Hepa1-6 cells.

  5. CD81 (show CD81 Proteins) promotes the microvillus formation and/or extension while tetraspanin CD82 inhibits these events. In addition, CD81 (show CD81 Proteins) enhances the outward bending of the plasma membrane while CD82 inhibits it.

  6. the CD82 tetraspanin is specifically recruited to pathogen-containing phagosomes prior to fusion with lysosomes.

  7. KAI1 has a role in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase

  8. Hypoxia-dependent induction of KAI1 was directly mediated by hypoxia-inducible factor-1alpha binding on the promoter, which subsequently caused increased recruitment of RNA polymerase II for transcriptional activation.

  9. An antibody to this protein that can specifically detect murine Kai1/CD82, should be useful in addressing the mechanism of action of Kai1 in metastatic suppression.

  10. gp78 (show AMFR Proteins) promotes sarcoma metastasis by targeting KAI1 for degradation

Human CD82 Molecule (CD82) interaction partners

  1. The overexpression of KAI1/CD82 inhibited the proliferation and invasion of OSCC-15 cells.

  2. Our present work therefore suggests that CD82 on EC is a potential target for anti-angiogenic therapy in VEGFR2 (show KDR Proteins)-dependent tumor angiogenesis.

  3. that a loss of KAI1/CD82 and an increase in PDGFR (show PDGFRB Proteins) expression in gliomas relate to a progressive tumor growth

  4. KAI1 underexpression is associated with gastric cancer.

  5. KAI1-induced decreases in VEGFC (show VEGFC Proteins) expression are mediated via Src (show SRC Proteins)/STAT3 (show STAT3 Proteins) signaling pathways in pancreatic cancer cells.

  6. The simultaneous overexpression of p12CDK2-AP1 (show FOSB Proteins) and CD82 significantly suppressed the in vivo tumor growth.

  7. Lack of expression of the KAI1 might indicate a more aggressive form of breast cancer.

  8. KAI1 and KISS1 (show KISS1 Proteins) are implicated in the pathogenesis and maintenance of endometriosis.

  9. Ubiquitously expressed CD82 restrains cell migration and cell invasion by modulating both cell-matrix and cell-cell adhesiveness and confining outside-in pro-motility signaling.

  10. Survivin (show BIRC5 Proteins), Bcl-2 (show BCL2 Proteins), and KAI1 are metastasis-related factors in cervical cancer. Overexpression of survivin (show BIRC5 Proteins) and Bcl-2 (show BCL2 Proteins), and low expression of KAI1 promotes cervical cancer progress and metastasis.

CD82 Protein Profile

Protein Summary

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with CD82

  • CD82 antigen (Cd82)
  • CD82 molecule (CD82)
  • Cd82 molecule (Cd82)
  • 4F9 protein
  • AA682076 protein
  • AL023070 protein
  • C33 protein
  • GR15 protein
  • IA4 protein
  • KAI1 protein
  • R2 protein
  • SAR2 protein
  • ST6 protein
  • TSPAN27 protein

Protein level used designations for CD82 Molecule Proteins (CD82)

C33 antigen , inducible membrane protein R2 , kangai 1 (suppression of tumorigenicity 6, prostate) , metastasis suppressor Kangai-1 homolog , CD82 antigen , kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) , metastasis suppressor Kangai-1 , tetraspanin-27 , tspan-27 , CD82 antigen (R2 leukocyte antigen antigen detected by monoclonal and antibody IA4)) , CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) , Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen , Kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) , kangai 1 (suppression of tumorigenicity 6), prostate

GENE ID SPECIES
12521 Mus musculus
3732 Homo sapiens
83628 Rattus norvegicus
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