Browse our anti-GADD45A (GADD45A) Antibodies

Full name:
anti-Growth Arrest and DNA-Damage-Inducible, alpha Antibodies (GADD45A)
On www.antibodies-online.com are 84 Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) Antibodies from 21 different suppliers available. Additionally we are shipping GADD45A Proteins (19) and GADD45A Kits (11) and many more products for this protein. A total of 121 GADD45A products are currently listed.
Synonyms:
AA545191, DDIT1, Gadd45, GADD45A, MGC53491, zgc:91795
list all antibodies Gene Name GeneID UniProt
GADD45A 13197 P48316
GADD45A 1647 P24522
GADD45A 25112  

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anti-Mouse (Murine) GADD45A Antibodies:

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Top referenced anti-GADD45A Antibodies

  1. Human Monoclonal GADD45A Primary Antibody for ELISA, WB - ABIN393701 : Sánchez, Pantoja-Uceda, Prieto, Diercks, Marcaida, Montoya, Campos-Olivas, Blanco: Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 393701

  2. Human Polyclonal GADD45A Primary Antibody for FACS, WB - ABIN650724 : Li, Morales, Hwang, Wagner, Boothman: DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis. in The Journal of biological chemistry 2008 (PubMed)
    Show all 5 references for 650724

  3. Human Polyclonal GADD45A Primary Antibody for EIA, WB - ABIN453659 : Kearsey, Coates, Prescott, Warbrick, Hall: Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1. in Oncogene 1995 (PubMed)
    Show all 4 references for 453659

  4. Human Polyclonal GADD45A Primary Antibody for FACS, WB - ABIN389281 : Al-Romaih, Sadikovic, Yoshimoto, Wang, Zielenska, Squire: Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells. in Neoplasia (New York, N.Y.) 2008 (PubMed)
    Show all 4 references for 389281

  5. Human Monoclonal GADD45A Primary Antibody for PLA, ELISA - ABIN560584 : Matteucci, Minutolo, Balestrieri, Marino-Merlo, Bramanti, Garaci, Macchi, Mastino: Inhibition of NF-?B activation sensitizes U937 cells to 3'-azido-3'-deoxythymidine induced apoptosis. in Cell death & disease 2011 (PubMed)
    Show all 2 references for 560584

  6. Human Polyclonal GADD45A Primary Antibody for IF (p), IHC (p) - ABIN685432 : Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. in International journal of nanomedicine 2014 (PubMed)

More Antibodies against GADD45A Interaction Partners

Xenopus laevis Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) interaction partners

  1. Gadd45a and Gadd45g (show GADD45G Antibodies) regulate neural development and exit from pluripotency in Xenopus.

Zebrafish Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) interaction partners

  1. Results provide evidence for a coupled mechanism of 5-methylcytosine (5-meC (show CCL28 Antibodies)) demethylation, whereby 5-meC (show CCL28 Antibodies) deaminase (AID) deaminates 5-meC (show CCL28 Antibodies), followed by thymine base excision by G:T mismatch-specific thymine glycosylase (Mbd4 (show MBD4 Antibodies)), promoted by Gadd45.

Pig (Porcine) Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) interaction partners

  1. GADD45A gene variants are associated with meat quality in pigs.

Mouse (Murine) Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) interaction partners

  1. Data show that loss of growth arrest and DNA-damage-inducible 45 alpha protein (Gadd45a) accelerates the onset of BCR-ABL driven leukemia in bone marrow recipient mice.

  2. by forming a complex with MEKK4 (show MAP3K4 Antibodies) in skeletal muscle fibers, Gadd45a increases MEKK4 (show MAP3K4 Antibodies) protein kinase (show CDK7 Antibodies) activity, which is both sufficient to induce skeletal muscle fiber atrophy and required for Gadd45a-mediated skeletal muscle fiber atrophy.

  3. Gadd45a may counteract hepatic fi brosis by regulating the activation of hepatic stellate cells via the inhibition of TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling.

  4. These data indicate that genotoxic stress-induced GADD45A expression in HSCs prevents their fatal transformation by directing them into differentiation and thereby clearing them from the system

  5. provide the novel evidence that GADD45A inhibits autophagy via impairing the BECN1 (show BECN1 Antibodies)-PIK3C3 (show PIK3C3 Antibodies) complex formation

  6. Results suggest the possibility that differential Gadd45a, Gadd45b (show GADD45B Antibodies) and Gadd45g (show GADD45G Antibodies) expression during development affects neurons, contributing cortical evolution and diversity

  7. GADD45a promoter regulation by a functional genetic variant is associated with acute mechanical lung injury.

  8. In SOD1 (show SOD1 Antibodies) and Neurotomized mice the results of this studysuggest LC3 (show MAP1LC3A Antibodies), Fn14 (show TNFRSF12A Antibodies), Bcl3 (show BCL3 Antibodies) and Gadd45a as candidate genes involved in the maintenance of the severe atrophic state.

  9. results for the first time demonstrate that nucleolin (show NCL Antibodies)-SUMO at K294R plays a critical role in its nucleus sequestration and gadd45alpha mRNA binding activity.

  10. Dendrin is dispensable for the function of the normal glomerular filtration barrier, and it interacts with Wtip (show WTIP Antibodies) and Gadd45a.

Human Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) interaction partners

  1. The findings indicate that p38alpha (show MAPK14 Antibodies) and GADD45alpha are involved in an enhanced vitamin D signaling on TRPV6 (show TRPV6 Antibodies) expression.

  2. the enhancement of GADD45A-mediated base excision repair modulated by ATF2 (show ATF2 Antibodies) might be a potential protective mechanism of visible red light.

  3. Data show that growth arrest and DNA-damage-inducible 45 alpha protein (Gadd45a) expression is up-regulated in chronic phase myelocytic leukemia, chronic (CML) patient samples but down-regulated in accelerated and blast crisis phase samples.

  4. These data revealed that Riboflavin plus ultraviolet (UV) pathogen reduction technology effectively inhibited proliferation and induced apoptosis of lymphocytes by promoting GADD45alpha expression, which subsequently activates p38 (show CRK Antibodies) and JNK (show MAPK8 Antibodies) signaling pathways.

  5. data suggest GADD45 proteins play a role in controlling HIV-1 transcription and in regulating HIV-1 latency

  6. Taken together, our results suggest that ROS (show ROS1 Antibodies) generation might be a predisposing event in berberine-induced mitochondrial apoptosis in EBV-transformed B cells through the upregulation of XAF1 (show XAF1 Antibodies) and GADD45alpha expression by MAPK (show MAPK1 Antibodies) and functional p53 (show TP53 Antibodies).

  7. Collective results lead us to conclude that GADD45alpha modulates curcumin sensitivity through activation of c-Abl (show ABL1 Antibodies) > JNK (show MAPK8 Antibodies) signaling in a mismatch repair-dependent manner

  8. BRCA1 may act as an important negative regulator in cell cycle progression and tumorigenesis through regulating the stability of Smad4 (show SMAD4 Antibodies); this defines a novel link that connects BRCA1 to TGF-beta1 (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) pathway.

  9. MiR (show MLXIP Antibodies)-362-5p promotes the malignancy of chronic myelocytic leukaemia via down-regulation of GADD45alpha

  10. these data suggest a dual function of GADD45a in oxidative DNA demethylation, to promote directly or indirectly TET1 (show TET1 Antibodies) activity and to enhance subsequent 5-formylcytosine/5-carboxylcytosine removal.

GADD45A Antigen Profile

Antigen Summary

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with GADD45A

  • growth arrest and DNA-damage-inducible, alpha (gadd45a) antibody
  • growth arrest and DNA-damage-inducible, alpha, b (gadd45ab) antibody
  • growth arrest and DNA-damage-inducible, alpha (GADD45A) antibody
  • growth arrest and DNA damage-inducible protein 45 (GADD45) antibody
  • growth arrest and DNA-damage-inducible 45 alpha (Gadd45a) antibody
  • growth arrest and DNA-damage-inducible, alpha (Gadd45a) antibody
  • AA545191 antibody
  • DDIT1 antibody
  • Gadd45 antibody
  • GADD45A antibody
  • MGC53491 antibody
  • zgc:91795 antibody

Protein level used designations for GADD45A

growth arrest and DNA-damage-inducible, alpha , growth arrest and DNA damage-inducible protein GADD45 alpha , growth arrest and DNA-damage-inducible protein 45 alpha , growth arrest and DNA-damage-inducible protein alpha , growth arrest and DNA damage-inducible protein 45 , Growth arrest and DNA-damage-inducible protein GADD45 alpha , DDIT-1 , DNA damage-inducible transcript 1 protein , DNA-damage inducible transcript 1 , DNA-damage-inducible transcript 1 , Gadd45alpha , growth arrest and DNA-damage-inducible protein GADD45 alpha , DNA damage-inducible transcript-1 , growth arrest and DNA-damage-inducible 45 alpha

GENE ID SPECIES
379224 Xenopus laevis
431763 Danio rerio
456929 Pan troglodytes
548905 Xenopus (Silurana) tropicalis
693255 Gallus gallus
701054 Macaca mulatta
733669 Sus scrofa
493656 Felis catus
13197 Mus musculus
1647 Homo sapiens
25112 Rattus norvegicus
505463 Bos taurus
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