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anti-Human HMGB1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended HMGB1 Antibody (supplied by: Log in to see )

Antigen
High-Mobility Group Box 1 (HMGB1) Antibodies
  • hmgb1
  • amphoterin
  • hmg-1
  • hmg1
  • hmg3
  • sbp-1
  • HMGB1
  • HMG1
  • HMG3
  • SBP-1
  • DEF
  • HMG-1
  • Hmg1
  • p30
  • Ac2-008
  • ik:tdsubc_1a5
  • wu:fb23c02
  • xx:tdsubc_1a5
  • zgc:56110
  • zgc:77104
  • Hmgb1
  • high-mobility group box 1
  • high mobility group box 1
  • high mobility group protein B1-like
  • high-mobility group box 1a
  • HMG-box transcription factor 1
  • hmgb1
  • HMGB1
  • Hmgb1
  • LOC100392312
  • LOC100754755
  • LOC100359149
  • hmgb1a
  • Hbp1
Epitope
AA 60-110
69
53
38
38
38
20
19
19
18
17
14
13
12
12
11
11
7
5
5
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
437
208
140
51
39
30
14
13
6
6
3
1
1
Host
Rabbit
241
205
4
4
2
2
Clonality
Polyclonal
Conjugate
This HMGB1 antibody is un-conjugated
27
20
18
16
8
8
8
7
7
7
7
7
7
6
6
5
5
5
5
3
2
2
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
366
189
128
128
105
83
45
19
12
12
6
5
3
2
1
1
1
1
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Catalog No. ABIN671616
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.096642 ABIN615020 IHC (p) WB Rabbit IgG Log in to see Polyclonal
12.096642 ABIN2506663 ICC IF IHC (p) WB Rabbit IgG Log in to see Polyclonal
12.096642 ABIN449594 IHC (p) IHC ELISA WB Mouse IgG2b kappa AA 1-215 Log in to see J2E1
12.096642 ABIN1107583 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal
12.096642 ABIN4319342 CyTOF FACS IHC IHC (p) SimWes WB Mouse IgG2b kappa A Box Domain, AA 9-79, full length Log in to see 19N10B7
12.096642 ABIN4319346 FACS IHC (p) WB Mouse IgG1 kappa A Box Domain, AA 9-79, full length Log in to see 19N15F4
12.096642 ABIN4319340 CyTOF FACS IHC IHC (p) SimWes WB Mouse IgG2b kappa A Box Domain, AA 9-79, full length Log in to see 19N10B7
12.096642 ABIN4319323 IHC (p) WB Rabbit IgG Log in to see Polyclonal
12.096642 ABIN4319337 FACS IHC (p) SimWes WB Rabbit Log in to see Polyclonal
1 ABIN250703 ELISA FACS ICC IF IHC IHC (p) SimWes WB Rabbit AA 100-200, Internal Region Log in to see Polyclonal 12
1 ABIN272158 IF IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN356226 EIA IHC (p) WB Mouse IgG2b AA 1-215, N-Term Log in to see J2E1
1 ABIN561286 IF IHC (p) ELISA WB Mouse IgG2a kappa AA 1-90, partial Log in to see 2F6 2
1 ABIN1326935 IF IHC (p) ELISA WB Mouse IgG1 kappa AA 1-215, full length Log in to see 1E6-E10 2
1 ABIN2854997 ICC IF IHC (p) IHC WB Rabbit IgG Center Log in to see Polyclonal
1 ABIN1536601 IHC (p) WB Mouse IgM AA 152-180, C-Term Log in to see 393CT23-1-4
1 ABIN614615 EIA IF IHC (p) WB Mouse IgG2a AA 1-216 Log in to see 1D5
1 ABIN561282 IF IHC (p) ELISA WB Mouse IgG2a kappa AA 1-215, full length Log in to see 1B11 2
1 ABIN561281 IF IHC (p) ELISA WB Mouse IgG2a kappa AA 1-215, full length Log in to see 1D5 5
1 ABIN2878832 IHC (p) ELISA WB Rabbit IgG AA 131-180 Log in to see Polyclonal

Top referenced anti-HMGB1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-HMGB1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Cytometry by Time of Flight (CyTOF) 2 Antibodies 5 Antibodies
ELISA 57 Antibodies 58 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 1 Antibodies
Flow Cytometry (FACS) 36 Antibodies 76 Antibodies
Immunochromatography (IC) 1 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 36 Antibodies
Immunofluorescence (IF) 44 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 40 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 30 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Simple Western (SimWes) 3 Antibodies
Western Blotting (WB) 104 Antibodies

General

Antigen High-Mobility Group Box 1 (HMGB1) Antibodies
Epitope AA 60-110
(69), (53), (38), (38), (38), (20), (19), (19), (18), (17), (14), (13), (12), (12), (11), (11), (7), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(437), (208), (140), (51), (39), (30), (14), (13), (6), (6), (3), (1), (1)
Host Rabbit
(241), (205), (4), (4), (2), (2)
Clonality
Polyclonal
Conjugate This HMGB1 antibody is un-conjugated
(27), (20), (18), (16), (8), (8), (8), (7), (7), (7), (7), (7), (7), (6), (6), (5), (5), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(366), (189), (128), (128), (105), (83), (45), (19), (12), (12), (6), (5), (3), (2), (1), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-HMGB1 Antibody

Target Details HMGB1 Application Details Handling References for anti-HMGB1 Antibody (ABIN671616) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human HMGB1
Isotype IgG

Target Details HMGB1

Product Details anti-HMGB1 Antibody Application Details Handling References for anti-HMGB1 Antibody (ABIN671616) Images back to top
Antigen
Alternative Name HMGB1 (HMGB1 Antibody Abstract)
Background

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).

Subcellular location: Nucleus


Synonyms: HMG1, HMG3, SBP-1, High mobility group protein B1, High mobility group protein 1, HMG-1, HMGB1
Gene ID 3146
UniProt P09429
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Chromatin Binding Proteins, Neurology
Pathways p53 Signaling

Application Details

Product Details anti-HMGB1 Antibody Target Details HMGB1 Handling References for anti-HMGB1 Antibody (ABIN671616) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-HMGB1 Antibody Target Details HMGB1 Application Details References for anti-HMGB1 Antibody (ABIN671616) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-HMGB1 Antibody (ABIN671616)

Product Details anti-HMGB1 Antibody Target Details HMGB1 Application Details Handling Images back to top
Product cited in:

Li, Xu, Xu, Cai, Sun, Yang, Sun, Lu: "Methotrexate affects HMGB1 expression in rheumatoid arthritis, and the downregulation of HMGB1 prevents rheumatoid arthritis progression." in: Molecular and cellular biochemistry, Vol. 420, Issue 1-2, pp. 161-70, 2016

Sun, Zhang, Cui, Chen, Xie, Zhou, Liu, Peng, Zhang: "High mobility group box-1 and its clinical value in breast cancer." in: OncoTargets and therapy, Vol. 8, pp. 413-9, 2015

Zhang, He, Wang, Zhou, Ma: "Omega-3 polyunsaturated fatty acids inhibit the increase in cytokines and chemotactic factors induced in vitro by lymph fluid from an intestinal ischemia-reperfusion injury model." in: Nutrition (Burbank, Los Angeles County, Calif.), Vol. 31, Issue 3, pp. 508-14, 2015

Luan, Kan, Xu, Lv, Jiang: "Rosmarinic acid protects against experimental diabetes with cerebral ischemia: relation to inflammation response." in: Journal of neuroinflammation, Vol. 10, pp. 28, 2013 Method employed by authors: Western Blotting (WB)

Zhao, Hu, Sun, Sun: "The high mobility group box 1 protein of Sciaenops ocellatus is a secreted cytokine that stimulates macrophage activation." in: Developmental and comparative immunology, Vol. 35, Issue 10, pp. 1052-8, 2011

Jiang, Fu, Tian, Zhu, Hou: "Curculigoside A attenuates experimental cerebral ischemia injury in vitro and vivo." in: Neuroscience, Vol. 192, pp. 572-9, 2011

Images

Product Details anti-HMGB1 Antibody Target Details HMGB1 Application Details Handling References for anti-HMGB1 Antibody (ABIN671616) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Formalin-fixed and paraffin embedded human endometrium carcinoma labeled Anti-HMGB1 P...
Immunohistochemistry (IHC) image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Formalin-fixed and paraffin embedded rat liver tissue labeled Anti-HMGB1 Polyclonal A...
ELISA image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Antigen: 2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16...
Flow Cytometry (FACS) image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Human HepG2 cell lysates probed with Rabbit Anti-HMGB1 Polyclonal Antibody, PE-Cy5 co...
Flow Cytometry (FACS) image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Rat splenocytes stained with Anti- HMGB1 Polyclonal Antibody, A488 Conjugated at 1:50.
Western Blotting (WB) image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Lane 1: Mouse Macrophages probed with Rabbit Anti-HMGB1 Polyclonal Antibody, Unconjug...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Formalin-fixed and paraffin embedded human endometrium carcinoma labeled Anti-HMGB1 P...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-HMGB1 antibody (High-Mobility Group Box 1) (AA 60-110) (ABIN671616) Formalin-fixed and paraffin embedded rat liver tissue labeled Anti-HMGB1 Polyclonal A...