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anti-Human p53 antibody for Radioimmunoassay

Recommended p53 Antibody (supplied by: Log in to see )

Antigen
Tumor Protein P53 (TP53) Antibodies
  • bbl
  • BCC7
  • bfy
  • bhy
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • LFS1
  • p44
  • P53
  • p53
  • tp53
  • TP53
  • Tp53
  • TpMs
  • Trp53
  • TRP53
  • wu:fb40d06
  • Xp53
  • zgc:111919
Epitope
AA 46-53
123
87
62
54
50
50
49
48
46
46
43
40
39
30
27
25
22
20
19
17
17
13
13
13
13
13
12
12
9
9
9
8
8
8
8
8
8
8
7
7
7
6
6
6
6
6
6
6
6
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
1760
319
269
99
34
19
13
11
11
10
10
9
5
4
4
4
3
3
3
2
2
2
1
Host
Mouse
1235
612
7
4
3
1
1
Clonality
Monoclonal
Conjugate
This p53 antibody is un-conjugated
59
49
34
31
23
23
15
15
14
14
14
14
14
14
13
4
4
4
4
4
4
4
4
4
4
3
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Radioimmunoassay (RIA), ELISA, Western Blotting (WB)
1378
581
528
319
314
303
234
156
99
87
52
39
35
17
16
12
12
11
11
9
4
3
3
3
2
2
2
1
1
1
1
1
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Catalog No. ABIN863095
$ 321.20
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008676689 ABIN152250 ChIP FACS IHC (fro) IHC (p) IP IHC RIA ELISA WB Mouse IgG1 Log in to see PAb 1801 5
0.0008676689 ABIN2482452 FACS IP RIA IHC ELISA WB FITC Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482455 FACS IP RIA IHC ELISA WB PerCP Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482442 FACS IP RIA IHC ELISA WB Atto 488 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482456 FACS IP RIA IHC ELISA WB PE Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482457 FACS IP RIA IHC ELISA WB Streptavidin Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482453 FACS IP RIA IHC ELISA WB HRP Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482449 FACS IP RIA IHC ELISA WB Alkaline Phosphatase (AP) Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482447 FACS IP RIA IHC ELISA WB Atto 680 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482451 FACS IP RIA IHC ELISA WB Biotin Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482448 FACS IP RIA IHC ELISA WB Atto 700 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482441 FACS IP RIA IHC ELISA WB Atto 390 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482445 FACS IP RIA IHC ELISA WB Atto 633 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482454 FACS IP RIA IHC ELISA WB PE-Atto 594 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482444 FACS IP RIA IHC ELISA WB Atto 594 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482446 FACS IP RIA IHC ELISA WB Atto 655 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482443 FACS IP RIA IHC ELISA WB Atto 565 Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN2482450 FACS IP RIA IHC ELISA WB APC Mouse AA 46-53 Log in to see Pab 1801 1
0.0008676689 ABIN492445 EIA FACS IHC (fro) IHC (p) IP RIA WB Mouse IgG1 AA 46-53 Log in to see Pab 1801
0.0008676689 ABIN1104760 IHC (fro) FACS IHC (p) IP RIA ELISA WB Mouse IgG1 Log in to see PAb1801

Top referenced anti-p53 antibody for Radioimmunoassay

Similar anti-p53 Antibodies

Application / Reactivity Human
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Cellular Assay (CA) 1 Antibodies
Chromatin Immunoprecipitation (ChIP) 11 Antibodies
Dot Blot (DB) 31 Antibodies
ELISA 550 Antibodies
ELISA (Capture) 2 Antibodies
ELISA (Detection) 2 Antibodies
Enzyme Immunoassay (EIA) 17 Antibodies
Flow Cytometry (FACS) 220 Antibodies
Gel Shift (GS) 3 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 35 Antibodies
Immunocytochemistry (ICC) 82 Antibodies
Immunodiffusion (ID) 16 Antibodies
Immunofluorescence (IF) 311 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 156 Antibodies
Immunohistochemistry (IHC) 515 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 11 Antibodies

General

Antigen Tumor Protein P53 (TP53) Antibodies
Epitope AA 46-53
(123), (87), (62), (54), (50), (50), (49), (48), (46), (46), (43), (40), (39), (30), (27), (25), (22), (20), (19), (17), (17), (13), (13), (13), (13), (13), (12), (12), (9), (9), (9), (8), (8), (8), (8), (8), (8), (8), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(1760), (319), (269), (99), (34), (19), (13), (11), (11), (10), (10), (9), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1)
Host Mouse
(1235), (612), (7), (4), (3), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This p53 antibody is un-conjugated
(59), (49), (34), (31), (23), (23), (15), (15), (14), (14), (14), (14), (14), (14), (13), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (1), (1)
Application Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Radioimmunoassay (RIA), ELISA, Western Blotting (WB)
(1378), (581), (528), (319), (314), (303), (234), (156), (99), (87), (52), (39), (35), (17), (16), (12), (12), (11), (11), (9), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-p53 Antibody

Target Details p53 Application Details Handling References for anti-p53 Antibody (ABIN863095) Images
Specificity Detects ~53 kDa.
Sensitivity 1 µg/mL of SMC-183 was sufficient for detection of p53 in 10 µg of HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Purification Protein G Purified
Immunogen Fusion protein (Human), amino acids 46-53
Clone Pab 1801

Target Details p53

Product Details anti-p53 Antibody Application Details Handling References for anti-p53 Antibody (ABIN863095) Images back to top
Antigen
Alternative Name p53 (TP53 Antibody Abstract)
Background The p53 protein (tumor protein 53 or TP53) is a DNA-binding cell cycle-regulating transcription factor that governs cell division and the fine balance between cell death and cell survival (1). P53 plays a critical role in tumor suppression and hence it is often described as "the guardian of the genome", "the guardian angel gene", or the "master watchman." This also refers to its role in conserving stability by preventing genome mutation (2). Defects in p53 are linked to >50 % of human cancers, and restoring p53 function to these cancer cells can induce growth arrest and apoptosis (3). When p53 has been damaged, it can also lead to autoimmune disorders (4, 5).
Cellular Localization: Cytoplasm | Nucleus | PML body | Endoplasmic Reticulum
Gene ID 7157
NCBI Accession NP_000537
UniProt P04637
Research Area Cancer, Cell Cycle, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling

Application Details

Product Details anti-p53 Antibody Target Details p53 Handling References for anti-p53 Antibody (ABIN863095) Images back to top
Application Notes Recommended Dilution: WB (1:1000), optimal dilutions for assays should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-p53 Antibody Target Details p53 Application Details References for anti-p53 Antibody (ABIN863095) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C

References for anti-p53 Antibody (ABIN863095)

Product Details anti-p53 Antibody Target Details p53 Application Details Handling Images back to top
Background publications

Hansen, Fischer, Chan, Chang, Baldwin, Aragon, Carter, Lilly, Nishimura, Weisbart, Reeves: "Antibody-mediated p53 protein therapy prevents liver metastasis in vivo." in: Cancer research, Vol. 67, Issue 4, pp. 1769-74, 2007

Georgescu, Săftoiu, Georgescu, Ciurea, Ciurea: "Correlations of proliferation markers, p53 expression and histological findings in colorectal carcinoma." in: Journal of gastrointestinal and liver diseases : JGLD, Vol. 16, Issue 2, pp. 133-9, 2007

Akere, Otegbayo: "Evaluation of the pattern and prognostic implications of anti-p53 in hepatocellular carcinoma." in: Singapore medical journal, Vol. 48, Issue 1, pp. 41-4, 2007

Di Cesare, Previti, Lombardo, Di Benedetto, Mazzù, Romano, De Luca, Lasco, Cucinotta: "Serum anti-p53 autoantibodies in patients with type 1 diabetes." in: Annals of clinical and laboratory science, Vol. 31, Issue 3, pp. 253-8, 2001

Images

Product Details anti-p53 Antibody Target Details p53 Application Details Handling References for anti-p53 Antibody (ABIN863095) back to top
Supplier Images
Western Blotting (WB) image for anti-p53 antibody (Tumor Protein P53) (AA 46-53) (ABIN863095) p53 Hela 20ug 1 in 1000 Western Blotting.