You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) p53 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended p53 Antibody (supplied by: Log in to see )

Antigen
Tumor Protein P53 (TP53) Antibodies
  • bbl
  • BCC7
  • bfy
  • bhy
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • LFS1
  • p44
  • P53
  • p53
  • tp53
  • TP53
  • Tp53
  • TpMs
  • Trp53
  • TRP53
  • wu:fb40d06
  • Xp53
  • zgc:111919
Epitope
AA 240-290, Wild Type
123
87
62
54
51
50
49
48
46
46
43
40
39
30
27
25
22
20
19
17
16
13
13
13
13
12
12
12
9
9
9
8
8
8
8
8
8
8
7
7
7
6
6
6
6
6
6
6
6
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1760
318
268
99
34
19
13
11
11
10
10
9
5
4
4
4
3
3
3
2
2
2
1
Host
Rabbit
1234
613
7
4
3
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
59
49
34
31
23
23
15
15
14
14
14
14
14
14
13
4
4
4
4
4
4
4
4
4
4
3
1
1
Application
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1378
582
529
319
315
302
235
155
99
87
53
39
35
17
16
12
12
11
10
9
4
3
3
3
2
2
2
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN723935
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008836048 ABIN677408 IF (p) IHC (p) WB Rabbit IgG AA 345-390, Wild Type Log in to see Polyclonal 1
0.0008836048 ABIN702895 IF (p) IHC (p) WB Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN2804970 IF (p) Alexa Fluor 594 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN874748 IF (p) Alexa Fluor 647 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN874746 IF (p) Alexa Fluor 350 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN874750 IF (p) Alexa Fluor 555 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN874747 IF (p) Alexa Fluor 488 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN702898 IF (p) Cy3 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN702899 IF (p) Cy5 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN702900 IF (p) Cy5.5 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN702901 IF (p) Cy7 Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN702902 IF (p) FITC Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.0008836048 ABIN2804980 IF (p) Alexa Fluor 594 Rabbit IgG pSer376 Log in to see Polyclonal
0.0008836048 ABIN2804978 IF (p) Alexa Fluor 594 Rabbit IgG pThr81 Log in to see Polyclonal
0.0008836048 ABIN2804977 IF (p) Alexa Fluor 594 Rabbit IgG pThr18 Log in to see Polyclonal
0.0008836048 ABIN2808148 IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 240-290 Log in to see Polyclonal
0.0008836048 ABIN878537 IF (p) Alexa Fluor 647 Rabbit IgG pThr81 Log in to see Polyclonal
0.0008836048 ABIN878540 IF (p) Alexa Fluor 350 Rabbit IgG pThr81 Log in to see Polyclonal
0.0008836048 ABIN878538 IF (p) Alexa Fluor 555 Rabbit IgG pThr81 Log in to see Polyclonal
0.0008836048 ABIN878539 IF (p) Alexa Fluor 488 Rabbit IgG pThr81 Log in to see Polyclonal

Top referenced anti-p53 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-p53 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 80 Antibodies 73 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 3 Antibodies
Flow Cytometry (FACS) 8 Antibodies
Immunochromatography (IC) 7 Antibodies
Immunocytochemistry (ICC) 16 Antibodies
Immunofluorescence (IF) 51 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 11 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 66 Antibodies
Immunohistochemistry (IHC) 66 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 41 Antibodies
Immunoprecipitation (IP) 36 Antibodies
Intracellular Staining (ICS) 1 Antibodies
Radioimmunoassay (RIA) 1 Antibodies
Western Blotting (WB) 184 Antibodies
Chromatin Immunoprecipitation (ChIP) 1 Antibodies
Dot Blot (DB) 11 Antibodies

General

Antigen Tumor Protein P53 (TP53) Antibodies
Epitope AA 240-290, Wild Type
(123), (87), (62), (54), (51), (50), (49), (48), (46), (46), (43), (40), (39), (30), (27), (25), (22), (20), (19), (17), (16), (13), (13), (13), (13), (12), (12), (12), (9), (9), (9), (8), (8), (8), (8), (8), (8), (8), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1760), (318), (268), (99), (34), (19), (13), (11), (11), (10), (10), (9), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1)
Host Rabbit
(1234), (613), (7), (4), (3), (1), (1)
Clonality
Polyclonal
Conjugate This p53 antibody is un-conjugated
(59), (49), (34), (31), (23), (23), (15), (15), (14), (14), (14), (14), (14), (14), (13), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (1), (1)
Application Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(1378), (582), (529), (319), (315), (302), (235), (155), (99), (87), (53), (39), (35), (17), (16), (12), (12), (11), (10), (9), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-p53 Antibody

Target Details p53 Application Details Handling References for anti-p53 Antibody (ABIN723935) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human P53
Isotype IgG

Target Details p53

Product Details anti-p53 Antibody Application Details Handling References for anti-p53 Antibody (ABIN723935) Images back to top
Antigen
Alternative Name P53 Protein (TP53 Antibody Abstract)
Background

Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.

Subcellular location: Cytoplasm, Nucleus


Synonyms: P53, BCC7, LFS1, TRP53, Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, TP53
Gene ID 7157
UniProt P04637
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling

Application Details

Product Details anti-p53 Antibody Target Details p53 Handling References for anti-p53 Antibody (ABIN723935) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-p53 Antibody Target Details p53 Application Details References for anti-p53 Antibody (ABIN723935) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-p53 Antibody (ABIN723935)

Product Details anti-p53 Antibody Target Details p53 Application Details Handling Images back to top
Product cited in:

Chen, Shi, Liu, Fang, Zhang, Zhao: "Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis." in: BMC cancer, Vol. 12, pp. 464, 2012 (1:1000).

Images

Product Details anti-p53 Antibody Target Details p53 Application Details Handling References for anti-p53 Antibody (ABIN723935) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-p53 antibody (Tumor Protein P53) (AA 240-290) (ABIN723935) Formalin-fixed and paraffin embedded human ovarian carcinoma labeled with Rabbit Anti...
SDS-PAGE (SDS) image for anti-p53 antibody (Tumor Protein P53) (AA 240-290) (ABIN723935) 1 rat brain, L2 human colon carcinoma lysates probed (ABIN723935) at 1:200 in 4 °C. F...
Immunofluorescence (IF) image for anti-p53 antibody (Tumor Protein P53) (AA 240-290) (ABIN723935) Image kindly submitted by Piotr Mamczur from Wroclaw University. Immunofluorescent lo...