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anti-Mouse (Murine) p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended p53 Antibody (supplied by: Log in to see )

Antigen
Tumor Protein P53 (TP53) Antibodies
  • bbl
  • BCC7
  • bfy
  • bhy
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • LFS1
  • p44
  • P53
  • p53
  • tp53
  • TP53
  • Tp53
  • TpMs
  • Trp53
  • TRP53
  • wu:fb40d06
  • Xp53
  • zgc:111919
Epitope
AA 14-389
156
103
87
67
66
65
56
52
52
52
47
46
42
40
31
30
28
25
25
22
22
21
20
17
17
14
14
14
14
14
12
11
11
10
10
9
9
8
8
8
7
7
7
7
7
7
6
6
6
6
6
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus), Yeast
2087
394
328
120
101
89
56
54
29
23
19
15
14
10
10
5
5
4
4
3
3
3
3
2
2
Host
Mouse
1254
931
7
4
3
1
1
Clonality
Monoclonal
Conjugate
This p53 antibody is un-conjugated
68
61
49
45
31
31
30
23
23
17
17
16
16
14
14
14
14
14
14
13
13
13
13
13
12
12
6
4
4
4
4
4
4
4
4
4
3
3
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
1659
732
564
492
442
421
397
230
194
170
53
38
35
17
16
12
12
11
11
9
9
4
3
3
3
2
2
2
1
1
1
1
1
Supplier
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Catalog No. ABIN152249
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.23808794 ABIN498795 IHC (p) WB Rabbit pSer20 Log in to see Polyclonal
0.23808794 ABIN498159 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.23808794 ABIN499003 IHC (p) WB Rabbit Log in to see Polyclonal
0.23808794 ABIN499004 IHC (p) WB Rabbit Log in to see Polyclonal
0.23808794 ABIN4342743 ICC IF IHC IHC (p) IP WB Rabbit pSer15 Log in to see Polyclonal 2
0.23808794 ABIN498886 IHC (p) WB Rabbit Log in to see Polyclonal
0.23808794 ABIN4342748 FACS ICC IF IHC IHC (p) SimWes WB Mouse IgG1 Log in to see 5-00E02
0.000899519 ABIN358195 EIA IHC (p) WB Rabbit Ig pThr18 Log in to see Polyclonal 5
0.000899519 ABIN967419 IHC (fro) IHC (p) IP WB Mouse IgG1 AA 14-289 Log in to see PAb 240 7
0.000899519 ABIN967420 IHC (fro) IHC (p) IP WB Mouse IgG1 AA 14-289 Log in to see PAb 240 7
0.000899519 ABIN319211 IHC (p) WB Rabbit pSer6 Log in to see Polyclonal 4
0.000899519 ABIN272049 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.000899519 ABIN272156 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.000899519 ABIN272050 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.000899519 ABIN677408 IF (p) IHC (p) WB Rabbit IgG AA 345-390, Wild Type Log in to see Polyclonal 1
0.000899519 ABIN723935 IF (cc) IF (p) IHC (p) WB Rabbit IgG AA 240-290, Wild Type Log in to see Polyclonal 3
0.000899519 ABIN127171 IHC (p) IP WB Rabbit pSer15 Log in to see Polyclonal
0.000899519 ABIN389626 DB IHC (p) WB Rabbit Ig pThr18 Log in to see Polyclonal
0.000899519 ABIN126922 IF IHC (p) IP WB Mouse IgG1 Ser20 Log in to see C6A5
0.000899519 ABIN317853 IF IHC (p) WB Rabbit Log in to see Polyclonal

Top referenced anti-p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-p53 Antibodies

Application / Reactivity Yeast Rat (Rattus)
ELISA 15 Antibodies 117 Antibodies
Flow Cytometry (FACS) 16 Antibodies 45 Antibodies
Immunocytochemistry (ICC) 7 Antibodies 45 Antibodies
Immunofluorescence (IF) 7 Antibodies 83 Antibodies
Immunohistochemistry (IHC) 15 Antibodies 86 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies 36 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Immunoprecipitation (IP) 15 Antibodies
Western Blotting (WB) 15 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Immunochromatography (IC) 7 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 12 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 72 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies

General

Antigen Tumor Protein P53 (TP53) Antibodies
Epitope AA 14-389
(156), (103), (87), (67), (66), (65), (56), (52), (52), (52), (47), (46), (42), (40), (31), (30), (28), (25), (25), (22), (22), (21), (20), (17), (17), (14), (14), (14), (14), (14), (12), (11), (11), (10), (10), (9), (9), (8), (8), (8), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus), Yeast
(2087), (394), (328), (120), (101), (89), (56), (54), (29), (23), (19), (15), (14), (10), (10), (5), (5), (4), (4), (3), (3), (3), (3), (2), (2)
Host Mouse
(1254), (931), (7), (4), (3), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This p53 antibody is un-conjugated
(68), (61), (49), (45), (31), (31), (30), (23), (23), (17), (17), (16), (16), (14), (14), (14), (14), (14), (14), (13), (13), (13), (13), (13), (12), (12), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (1), (1)
Application Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(1659), (732), (564), (492), (442), (421), (397), (230), (194), (170), (53), (38), (35), (17), (16), (12), (12), (11), (11), (9), (9), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 19 references available
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Product Details anti-p53 Antibody

Target Details p53 Application Details Handling References for anti-p53 Antibody (ABIN152249) Images
Specificity This monoclonal recognizes both mutant forms and wild-type human p53 under denaturing conditions.
No Cross-Reactivity Xenopus laevis
Cross-Reactivity (Details) Yeast reactivity reported in scientific literature (PMID: 8710879) Does not cross-react with Xenopus laevis. Not yet tested in other species.
Purification Protein G purified
Immunogen Gel-purified p53-beta-galactosidase fusion protein containing murine p53 from aa 14-389 (derived from pSV53C cDNA clone).
Clone PAb 240
Isotype IgG1 kappa

Target Details p53

Product Details anti-p53 Antibody Application Details Handling References for anti-p53 Antibody (ABIN152249) Images back to top
Antigen
Alternative Name p53 (TP53 Antibody Abstract)
Background Gene Symbol: TP53
Research Area DNA/RNA, Cell Cycle, Transcription Factors, Apoptosis/Necrosis, Cancer
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling

Application Details

Product Details anti-p53 Antibody Target Details p53 Handling References for anti-p53 Antibody (ABIN152249) Images back to top
Application Notes Western Blot 1:1000-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:250-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 10 μg/mg, Immunohistochemistry-Paraffin 1:250-1:500, Immunohistochemistry-Frozen
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-p53 Antibody Target Details p53 Application Details References for anti-p53 Antibody (ABIN152249) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

References for anti-p53 Antibody (ABIN152249)

Product Details anti-p53 Antibody Target Details p53 Application Details Handling Images back to top
Product cited in:

Shi, Ma, Zhou, Fu: "Renal Protective Effects of 17β-Estradiol on Mice with Acute Aristolochic Acid Nephropathy." in: Molecules (Basel, Switzerland), Vol. 21, Issue 10, 2016

Ge, Pettan-Brewer, Morton, Carter, Fatemi, Rabinovitch, Ladiges: "Mitochondrial catalase suppresses naturally occurring lung cancer in old mice." in: Pathobiology of aging & age related diseases, Vol. 5, pp. 28776, 2015 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry

Biswas, Mitchell, Johnson: "E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis." in: Cancer research, Vol. 74, Issue 12, pp. 3369-77, 2014 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Lange, Bedford, Reh, Wittschieben, Carbajal, Kusewitt, DiGiovanni, Wood: "Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 8, pp. E687-96, 2013 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Jensen, Factor, Fantozzi, Helin, Huh, Thorgeirsson: "Reduced hepatic tumor incidence in cyclin G1-deficient mice." in: Hepatology (Baltimore, Md.), Vol. 37, Issue 4, pp. 862-70, 2003 (Sample species: Mouse (Murine)). Further details: Western Blotting

Asher, Lotem, Cohen, Sachs, Shaul: "Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 3, pp. 1188-93, 2001 (Sample species: Mouse (Murine)). Further details: Western Blotting

Jones, Turner, McIlwrath, Brown, Dive: "Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53." in: Molecular pharmacology, Vol. 53, Issue 5, pp. 819-26, 1998 (Sample species: Human). Further details: Immunoprecipitation

Blagosklonny, Toretsky, Bohen, Neckers: "Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8379-83, 1996 (Sample species: Yeast). Further details: Immunoprecipitation

Bargonetti, Manfredi, Chen, Marshak, Prives: "A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein." in: Genes & development, Vol. 7, Issue 12B, pp. 2565-74, 1994 (Sample species: Human). Further details: Western Blotting

Rubio, von Deimling, Yandell, Wiestler, Gusella, Louis: "Accumulation of wild type p53 protein in human astrocytomas." in: Cancer research, Vol. 53, Issue 15, pp. 3465-7, 1993 (Sample species: Human). Further details: Immunohistochemistry (Frozen Sections)

Halazonetis, Davis, Kandil: "Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA." in: The EMBO journal, Vol. 12, Issue 3, pp. 1021-8, 1993 (Sample species: Human). Further details: Western Blotting,Immunoprecipitation

Eccles, Brett, Lessells, Gruber, Lane, Steel, Leonard: "Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma." in: British journal of cancer, Vol. 65, Issue 1, pp. 40-4, 1992 (Sample species: Human). Further details: Immunohistochemistry (Frozen Sections)

Somers, Merrick, Lopez, Incognito, Schechter, Casey: "Frequent p53 mutations in head and neck cancer." in: Cancer research, Vol. 52, Issue 21, pp. 5997-6000, 1992 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Remvikos, Tominaga, Hammel, Laurent-Puig, Salmon, Dutrillaux, Thomas: "Increased p53 protein content of colorectal tumours correlates with poor survival." in: British journal of cancer, Vol. 66, Issue 4, pp. 758-64, 1992 (Sample species: Human). Further details: ELISA,Flow Cytometry

Cunningham, Lust, Schaid, Bren, Carpenter, Rizza, Kovach, Thibodeau: "Expression of p53 and 17p allelic loss in colorectal carcinoma." in: Cancer research, Vol. 52, Issue 7, pp. 1974-80, 1992 (Sample species: Human). Further details: Immunohistochemistry

Farrell, Allan, Shanahan, Vousden, Crook: "p53 is frequently mutated in Burkitt's lymphoma cell lines." in: The EMBO journal, Vol. 10, Issue 10, pp. 2879-87, 1991 Further details: Immunoprecipitation

Martinez, Georgoff, Martinez, Levine: "Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein." in: Genes & development, Vol. 5, Issue 2, pp. 151-9, 1991 (Sample species: Rat (Rattus)). Further details: Immunocytochemistry,Immunofluorescence

Davidoff, Humphrey, Iglehart, Marks: "Genetic basis for p53 overexpression in human breast cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 5006-10, 1991 (Sample species: Human). Further details: Immunohistochemistry

Gannon, Greaves, Iggo, Lane: "Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form." in: The EMBO journal, Vol. 9, Issue 5, pp. 1595-602, 1990 Further details: Western Blotting,Immunoprecipitation,ELISA,Immunohistochemistry

Images

Product Details anti-p53 Antibody Target Details p53 Application Details Handling References for anti-p53 Antibody (ABIN152249) back to top
Supplier Images
 image for anti-p53 antibody (Tumor Protein P53) (AA 14-389) (ABIN152249) Flow (Intracellular): p53 Antibody (PAb 240) [ABIN152249] - An intracellular stain wa...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-p53 antibody (Tumor Protein P53) (AA 14-389) (ABIN152249) Immunohistochemistry-Paraffin: p53 Antibody (PAb 240) [ABIN152249] - p53 was detected...
Immunofluorescence (IF) image for anti-p53 antibody (Tumor Protein P53) (AA 14-389) (ABIN152249) Immunocytochemistry/Immunofluorescence: p53 Antibody (PAb 240) [ABIN152249] - HeLa ce...
Western Blotting (WB) image for anti-p53 antibody (Tumor Protein P53) (AA 14-389) (ABIN152249) Western Blot: p53 Antibody (PAb 240) [ABIN152249] - WB analysis of p53 in MCF7 and He...