You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Rat (Rattus) p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended p53 Antibody (supplied by: Log in to see )

Antigen
Tumor Protein P53 (TP53) Antibodies
  • bbl
  • BCC7
  • bfy
  • bhy
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • LFS1
  • p44
  • P53
  • p53
  • tp53
  • TP53
  • Tp53
  • TpMs
  • Trp53
  • TRP53
  • wu:fb40d06
  • Xp53
  • zgc:111919
Reactivity
Human, Mouse (Murine), Rat (Rattus)
2048
380
309
124
102
93
56
54
27
23
19
16
13
11
10
10
5
4
4
3
3
2
2
1
Host
Rabbit
1240
916
7
4
3
1
1
Clonality
Polyclonal
Conjugate
This p53 antibody is un-conjugated
66
61
47
44
31
31
23
23
17
17
16
16
16
14
14
14
14
14
13
13
13
13
13
13
13
12
12
4
4
4
4
4
4
4
4
4
3
3
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1657
717
558
487
437
428
397
237
196
156
53
39
35
17
16
13
12
11
11
9
9
4
3
3
3
2
2
2
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN499003
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34425658 ABIN499004 IHC (p) WB Rabbit Log in to see Polyclonal
0.34425658 ABIN498159 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089731865 ABIN967420 IHC (fro) IHC (p) IP WB Mouse IgG1 AA 14-289 Log in to see PAb 240 7
0.00089731865 ABIN967419 IHC (fro) IHC (p) IP WB Mouse IgG1 AA 14-289 Log in to see PAb 240 7
0.00089731865 ABIN723935 IF (cc) IF (p) IHC (p) WB Rabbit IgG AA 240-290, Wild Type Log in to see Polyclonal 1
0.00089731865 ABIN677408 IF (p) IHC (p) WB Rabbit IgG AA 345-390, Wild Type Log in to see Polyclonal 1
0.00089731865 ABIN272049 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089731865 ABIN272050 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089731865 ABIN272156 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089731865 ABIN271765 IHC (p) WB Rabbit Log in to see Polyclonal
0.00089731865 ABIN127171 IHC (p) IP WB Rabbit pSer15 Log in to see Polyclonal
0.00089731865 ABIN126922 IF IHC (p) IP WB Mouse IgG1 Ser20 Log in to see C6A5
0.00089731865 ABIN492445 EIA FACS IHC (fro) IHC (p) IP RIA WB Mouse IgG1 AA 46-53 Log in to see Pab 1801
0.00089731865 ABIN318091 IHC (p) IP WB Rabbit pSer15 Log in to see Polyclonal
0.00089731865 ABIN723366 IF (p) IHC (p) WB Mouse IgG Log in to see D2F7 1
0.00089731865 ABIN702895 IF (p) IHC (p) WB Rabbit IgG AA 5-55, pSer20 Log in to see Polyclonal
0.00089731865 ABIN317853 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.00089731865 ABIN1740217 ELISA ICC IF IHC (p) Rabbit IgG Lys379, acLys379 Log in to see Polyclonal
0.00089731865 ABIN1740218 IHC (p) ELISA WB Rabbit IgG N-Term Log in to see Polyclonal
0.00089731865 ABIN1740222 IF IHC (p) ELISA WB Rabbit IgG C-Term Log in to see Polyclonal

Top referenced anti-p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-p53 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 1572 Antibodies 282 Antibodies 224 Antibodies
Transfected Cell Culture (TCC) 1 Antibodies
RNA Interference (RNAi) 1 Antibodies
Radioimmunoassay (RIA) 54 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies
Intracellular Staining (ICS) 3 Antibodies 1 Antibodies 1 Antibodies
Intracellular Flow Cytometry (ICFC) 4 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 402 Antibodies 82 Antibodies 72 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 486 Antibodies 81 Antibodies

General

Antigen Tumor Protein P53 (TP53) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(2048), (380), (309), (124), (102), (93), (56), (54), (27), (23), (19), (16), (13), (11), (10), (10), (5), (4), (4), (3), (3), (2), (2), (1)
Host Rabbit
(1240), (916), (7), (4), (3), (1), (1)
Clonality
Polyclonal
Conjugate This p53 antibody is un-conjugated
(66), (61), (47), (44), (31), (31), (23), (23), (17), (17), (16), (16), (16), (14), (14), (14), (14), (14), (13), (13), (13), (13), (13), (13), (13), (12), (12), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(1657), (717), (558), (487), (437), (428), (397), (237), (196), (156), (53), (39), (35), (17), (16), (13), (12), (11), (11), (9), (9), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-p53 Antibody

Target Details p53 Application Details Handling Images
Specificity This antibody detects endogenous levels of p53 protein. (region surrounding Leu369)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details p53

Product Details anti-p53 Antibody Application Details Handling Images back to top
Antigen
Alternative Name p53 (TP53) (TP53 Antibody Abstract)
Background P53 is a DNA-binding, oligomerization domain and transcription activation domain-containing tumor suppressor that upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation and cell cycle control mechanisms. p53 localizes to the nucleus yet can be chaperoned to the cytoplasm by the negative regulator MDM2, an E3 ubiquitin ligase that is upregulated in the presence of active p53, where MDM2 polyubiquitinates p53 for proteasome targeting. p53 can assemble into tetramers in the absence of DNA, fluctuates between latent and active (DNA-binding) conformations, and is differentially activated through posttranslational modifications including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) (amino acids 110-286) of p53 can compromise energetically favorable association with cis elements and are implicated in several human cancers.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
Molecular Weight approx. 53, 43 kDa
Gene ID 7157
NCBI Accession NP_000537
UniProt P04637
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling

Application Details

Product Details anti-p53 Antibody Target Details p53 Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-p53 Antibody Target Details p53 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-p53 Antibody Target Details p53 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-p53 antibody (Tumor Protein P53) (ABIN499003) Immunohistochemistry (IHC) analyzes of p53 antibody in paraffin-embedded human...
Western Blotting (WB) image for anti-p53 antibody (Tumor Protein P53) (ABIN499003) Western blot (WB) analysis of p53 antibody in extracts from HT-29 cells.