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|Application / Reactivity||Human||Mouse (Murine)||Rat (Rattus)||Cow (Bovine)|
|Immunofluorescence (fixed cells) (IF/ICC)||4 Antibodies||4 Antibodies||3 Antibodies|
|Western Blotting (WB)||160 Antibodies||49 Antibodies||43 Antibodies||8 Antibodies|
|Immunoprecipitation (IP)||17 Antibodies||6 Antibodies||3 Antibodies||1 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||20 Antibodies||14 Antibodies||11 Antibodies||3 Antibodies|
|Immunohistochemistry (IHC)||47 Antibodies||23 Antibodies||18 Antibodies||2 Antibodies|
|Antigen||Peroxiredoxin 1 (PRDX1) Antibodies|
|Epitope||AA 1-146 Alternatives|
|Reactivity||Cow (Bovine), Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This Peroxiredoxin 1 antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-Peroxiredoxin 1 AntibodyTarget Details Peroxiredoxin 1 Application Details Handling Images
|Specificity||Recognizes Peroxiredoxin-1 (PRDX1).|
Species reactivity (expected):Rat (98 %) and Bovine (95 %), Xenopus tropicalis (83 %).
Species reactivity (tested):Human and Mouse.
|Purification||Affinity Chromatography on Protein A|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 146 of Peroxiredoxin-1/PRDX1.|
Target Details Peroxiredoxin 1Product Details anti-Peroxiredoxin 1 Antibody Application Details Handling Images back to top
|Alternative Name||Peroxiredoxin-1 / PRDX1 (PRDX1 Antibody Abstract)|
|Background||Peroxiredoxin 1 is involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It is constitutively expressed in most human cells, is induced to higher levels upon serum stimulation in untransformed and transformed cells.Synonyms: NKEF-A, NKEFA PAGA, Natural killer cell-enhancing factor A, PAG, PAGB, PRDX-1, Proliferation-associated gene protein, Prx-1, Prx1, TDPX2, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2|
|Gene ID||5052, 9606|
|Pathways||p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events|
Application DetailsProduct Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Handling Images back to top
Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200. Positive Controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details Images back to top
|Buffer||1xPBS, 1 % BSA, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative|
|Precaution of Use||This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage Comment||Store the antibody undiluted (in aliquots) at -20 °C.|
ImagesProduct Details anti-Peroxiredoxin 1 Antibody Target Details Peroxiredoxin 1 Application Details Handling back to top