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anti-Rat (Rattus) PML antibody for Immunohistochemistry

Recommended PML Antibody (supplied by: Log in to see )

Antigen
Promyelocytic Leukemia (PML) Antibodies
  • PML
  • MYL
  • PP8675
  • RNF71
  • TRIM19
  • 1200009E24Rik
  • AI661194
  • Trim19
  • RGD1562602
  • promyelocytic leukemia
  • PML
  • Pml
Epitope
C-Term
15
14
8
7
7
6
5
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
117
28
10
1
1
1
1
Host
Rabbit
94
40
Clonality
Polyclonal
Conjugate
This PML antibody is un-conjugated
5
5
3
3
3
3
Application
Immunohistochemistry (IHC), Western Blotting (WB)
117
46
43
42
27
24
17
7
6
5
4
3
2
2
1
1
1
Options
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Available images

Catalog No. ABIN2777721
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN3021659 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2894095 IHC WB Rabbit Log in to see Polyclonal
1 ABIN1994884 IHC WB Rabbit IgG Log in to see
1 ABIN2920703 IHC WB Rabbit IgG Log in to see Polyclonal

Similar anti-PML Antibodies

Application / Reactivity Mouse (Murine) Human Rat (Rattus) Cow (Bovine) Guinea Pig Horse (Equine) Dog (Canine) Pig (Porcine) Rabbit
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies 4 Antibodies
Western Blotting (WB) 29 Antibodies 101 Antibodies 11 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies 1 Antibodies 1 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 4 Antibodies 1 Antibodies
Immunoprecipitation (IP) 8 Antibodies 10 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 24 Antibodies 6 Antibodies 2 Antibodies 1 Antibodies 1 Antibodies

General

Antigen Promyelocytic Leukemia (PML) Antibodies
Epitope C-Term
(15), (14), (8), (7), (7), (6), (5), (5), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(117), (28), (10), (1), (1), (1), (1)
Host Rabbit
(94), (40)
Clonality
Polyclonal
Conjugate This PML antibody is un-conjugated
(5), (5), (3), (3), (3), (3)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(117), (46), (43), (42), (27), (24), (17), (7), (6), (5), (4), (3), (2), (2), (1), (1), (1)
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Product Details anti-PML Antibody

Target Details PML Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN981889
Sequence EGPSTLRVLD ENLADPQAED RPLVFFDLKI DNETQKISQL AAVNRESKFR
Specificity Isoform 1, 9, 10 and 11 specific
Predicted Reactivity Cow: 100%, Dog: 92%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 92%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against PML. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human PML

Target Details PML

Product Details anti-PML Antibody Application Details Handling Images back to top
Antigen
Alternative Name PML (PML Antibody Abstract)
Background PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions, all variants encode the same N-terminus.
Alias Symbols: MYL, PP8675, RNF71, TRIM19
Protein Interaction Partner: RPL11, RPL5, SUMO1, UBC, TP53, SUMO2, SUMO3, MDM2, RNF4, EGFR, NCOA2, SP100, DAXX, MAPK7, HDAC1, ATXN1, ATRX, ASF1A, EHMT2, HIRA, HTT, H3F3A, ATF7IP, PML, JAK1, EIF4E, GLIS2, UBE2I, smt3, HDAC11, HDAC6, LMNA, RNF111, CDK6, CDK2, CDK1, CASP8AP2, RBX1, SH3G
Protein Size: 540
Molecular Weight 59 kDa
Gene ID 5371
UniProt P29590, A4VCI9
Research Area Cancer
Pathways p53 Signaling, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus

Application Details

Product Details anti-PML Antibody Target Details PML Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 540 AA

Restrictions For Research Use only

Handling

Product Details anti-PML Antibody Target Details PML Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-PML Antibody Target Details PML Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-PML antibody (Promyelocytic Leukemia) (C-Term) (ABIN2777721) anti-Promyelocytic Leukemia (PML) (C-Term) antibody
Immunohistochemistry (IHC) image for anti-PML antibody (Promyelocytic Leukemia) (C-Term) (ABIN2777721) anti-Promyelocytic Leukemia (PML) (C-Term) antibody (Image 2)