anti-Human XPC antibody for Western Blotting

Recommended XPC Antibody (supplied by: Log in to see )

Antigen
Xeroderma Pigmentosum, Complementation Group C (XPC) Antibodies
  • RAD4
  • XP3
  • XPCC
  • xeroderma pigmentosum, complementation group C
  • XPC
  • LOC100346279
  • Xpc
Reactivity
Human, Mouse (Murine)
98
33
20
1
Host
Mouse
75
28
Clonality
Monoclonal
Conjugate
This XPC antibody is un-conjugated
8
8
7
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
77
32
31
27
23
20
13
5
2
2
1
1
Supplier
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Catalog No. ABIN151924
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2182703 ABIN1882000 WB Rabbit AA 154-183, N-Term Log in to see Polyclonal 1
3.2182703 ABIN188792 IP WB Rabbit AA 890-940 Log in to see Polyclonal 2
3.2182703 ABIN2855495 ICC IF IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
3.2182703 ABIN2737826 WB Rabbit IgG Log in to see Polyclonal
3.2182703 ABIN2967153 IHC WB Rabbit Log in to see Polyclonal
3.2182703 ABIN5532381 WB Rabbit Ig Fraction AA 154-183, N-Term Log in to see Polyclonal
3.2182703 ABIN4366415 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal
1 ABIN719171 IF (p) IHC (p) WB Rabbit IgG AA 880-920 Log in to see Polyclonal 1
1 ABIN396711 ELISA WB Mouse IgG2a kappa AA 141-251 Log in to see 6D11 5
1 ABIN1583828 ELISA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN719180 IHC (p) WB HRP Rabbit IgG AA 880-920 Log in to see Polyclonal
1 ABIN790293 IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN719173 IHC (p) WB Biotin Rabbit IgG AA 880-920 Log in to see Polyclonal
1 ABIN563389 ELISA WB Mouse IgG2a kappa AA 141-250, partial Log in to see 6D11
1 ABIN1829132 ELISA WB Mouse IgG2a, kappa AA 141-250 Log in to see 6D11
1 ABIN2469790 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN563388 ELISA WB Mouse AA 141-250, partial Log in to see Polyclonal
1 ABIN1948984 ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 154-183 Log in to see Polyclonal
1 ABIN1948985 ELISA WB FITC Rabbit IgG AA 154-183 Log in to see Polyclonal
1 ABIN1948986 ELISA WB Biotin Rabbit IgG AA 154-183 Log in to see Polyclonal

General

Antigen Xeroderma Pigmentosum, Complementation Group C (XPC) Antibodies
Reactivity Human, Mouse (Murine)
(98), (33), (20), (1)
Host Mouse
(75), (28)
Clonality (Clone)
Monoclonal   ( )
Conjugate This XPC antibody is un-conjugated
(8), (8), (7), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
(77), (32), (31), (27), (23), (20), (13), (5), (2), (2), (1), (1)
Pubmed 18 references available
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Product Details anti-XPC Antibody

Target Details XPC Application Details Handling References for anti-XPC antibody (ABIN151924) Images
Purification Protein G purified
Immunogen Recombinant XPC purified from E. coli
Clone 3-26
Isotype IgG1

Target Details XPC

Product Details anti-XPC Antibody Application Details Handling References for anti-XPC antibody (ABIN151924) Images back to top
Antigen
Alternative Name XPC (XPC Antibody Abstract)
Background Gene Symbol: XPC
Gene ID 7508
UniProt Q01831
Pathways p53 Signaling, DNA Damage Repair

Application Details

Product Details anti-XPC Antibody Target Details XPC Handling References for anti-XPC antibody (ABIN151924) Images back to top
Application Notes Western Blot 1:500-1:3000, Immunohistochemistry 1:100-1:1000, Immunocytochemistry/Immunofluorescence 1:100-1:1000, Immunohistochemistry-Paraffin 1:100-1:1000WB: Detects an approx. 113 kDa.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-XPC Antibody Target Details XPC Application Details References for anti-XPC antibody (ABIN151924) Images back to top
Format Liquid
Buffer PBS ( pH 7.2)
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

References for anti-XPC antibody (ABIN151924)

Product Details anti-XPC Antibody Target Details XPC Application Details Handling Images back to top
Product cited in:

Beresova, Vesela, Chamrad, Voller, Yamada, Furst, Lenobel, Chroma, Gursky, Krizova, Mistrik, Bartek: "Role of DNA Repair Factor Xeroderma Pigmentosum Protein Group C in Response to Replication Stress As Revealed by DNA Fragile Site Affinity Chromatography and Quantitative Proteomics." in: Journal of proteome research, Vol. 15, Issue 12, pp. 4505-4517, 2016

Berra, de Oliveira, Garcia, Rocha, Lerner, Lima, Baptista, Menck: "Nucleotide excision repair activity on DNA damage induced by photoactivated methylene blue." in: Free radical biology & medicine, Vol. 61, pp. 343-56, 2014 (Sample species: Human). Further details: Western Blotting

Mohni, Kavanaugh, Cortez: "ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency." in: Cancer research, Vol. 74, Issue 10, pp. 2835-45, 2014 (Sample species: Human). Further details: Western Blotting

Kothandapani, Gopalakrishnan, Kahali, Reisman, Patrick: "Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity." in: Experimental cell research, Vol. 318, Issue 16, pp. 1973-86, 2012 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Muenyi, States, Masters, Fan, Helm, States et al.: "Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal ..." in: Journal of ovarian research, Vol. 4, pp. 9, 2011 (Sample species: Human). Further details: Western Blotting

Takedachi, Saijo, Tanaka: "DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA." in: Molecular and cellular biology, Vol. 30, Issue 11, pp. 2708-23, 2010 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Acu, Liu, Suino-Powell, Mooney, DAssoro, Rowland, Muotri, Correa, Niu, Kumar, Salisbury: "Coordination of centrosome homeostasis and DNA repair is intact in MCF-7 and disrupted in MDA-MB 231 breast cancer cells." in: Cancer research, Vol. 70, Issue 8, pp. 3320-8, 2010 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

de Feraudy, Ridd, Richards, Kwok, Revet, Oh, Feeney, Cleaver: "The DNA damage-binding protein XPC is a frequent target for inactivation in squamous cell carcinomas." in: The American journal of pathology, Vol. 177, Issue 2, pp. 555-62, 2010 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Rezvani, Mahfouf, Ali, Chemin, Ged, Kim, de Verneuil, Taïeb, Bickers, Mazurier: "Hypoxia-inducible factor-1alpha regulates the expression of nucleotide excision repair proteins in keratinocytes." in: Nucleic acids research, Vol. 38, Issue 3, pp. 797-809, 2010 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Klein, Nigg: "SUMO-dependent regulation of centrin-2." in: Journal of cell science, Vol. 122, Issue Pt 18, pp. 3312-21, 2009 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Yan, Seo, Kinsella: "Differential cellular responses to prolonged LDR-IR in MLH1-proficient and MLH1-deficient colorectal cancer HCT116 cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6912-20, 2009 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Ferguson-Yates, Li, Dong, Hsiao, Oh: "Impaired repair of cyclobutane pyrimidine dimers in human keratinocytes deficient in p53 and p63." in: Carcinogenesis, Vol. 29, Issue 1, pp. 70-5, 2008 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Wang, Liu, Matsuda, Plunkett: "Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair." in: Cancer research, Vol. 68, Issue 10, pp. 3881-9, 2008 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Laposa, Huang, Cleaver: "Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 4, pp. 1389-94, 2007 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Lovejoy, Lock, Yenamandra, Cortez: "DDB1 maintains genome integrity through regulation of Cdt1." in: Molecular and cellular biology, Vol. 26, Issue 21, pp. 7977-90, 2006

Ferguson, Oh: "Proficient global nucleotide excision repair in human keratinocytes but not in fibroblasts deficient in p53." in: Cancer research, Vol. 65, Issue 19, pp. 8723-9, 2005 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Background publications

de Laat, Jaspers, Hoeijmakers: "Molecular mechanism of nucleotide excision repair." in: Genes & development, Vol. 13, Issue 7, pp. 768-85, 1999

Aboussekhra, Biggerstaff, Shivji, Vilpo, Moncollin, Podust, Protić, Hübscher, Egly, Wood: "Mammalian DNA nucleotide excision repair reconstituted with purified protein components." in: Cell, Vol. 80, Issue 6, pp. 859-68, 1995

Images

Product Details anti-XPC Antibody Target Details XPC Application Details Handling References for anti-XPC antibody (ABIN151924) back to top
Supplier Images
Western Blotting (WB) image for anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (ABIN151924) Western blot analysis of human XPC protein using anti-XPC (3.26) monoclonal antibody ...
Immunofluorescence (IF) image for anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (ABIN151924) anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (Image 2)
Western Blotting (WB) image for anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (ABIN151924) anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (Image 3)
Western Blotting (WB) image for anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (ABIN151924) Western Blot: XPC Antibody (3.26) [ABIN151924] - Whole cell extracts (30 ug) was sepa...
Western Blotting (WB) image for anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (ABIN151924) Western Blot: XPC Antibody (3.26) [ABIN151924] - HeLa whole cell lysate.
Immunofluorescence (IF) image for anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (ABIN151924) Immunocytochemistry/Immunofluorescence: XPC Antibody (3.26) [ABIN151924] - HeLa cells...
Immunofluorescence (IF) image for anti-Xeroderma Pigmentosum, Complementation Group C (XPC) antibody (ABIN151924) Immunocytochemistry/Immunofluorescence: XPC Antibody (3.26) [ABIN151924] - Analysis o...