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Browse our ENPEP Proteins (ENPEP)

Full name:
Glutamyl Aminopeptidase (Aminopeptidase A) Proteins (ENPEP)
On www.antibodies-online.com are 12 Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP) Proteins from 5 different suppliers available. Additionally we are shipping ENPEP Antibodies (138) and ENPEP Kits (11) and many more products for this protein. A total of 168 ENPEP products are currently listed.
Synonyms:
6030431M22Rik, APA, Bp-1/6C3, CD249, gp160, im:7152184, Ly-51, Ly51, si:ch211-146m5.2
list all proteins Gene Name GeneID UniProt
ENPEP 13809 P16406
ENPEP 64017 P50123
ENPEP 2028 Q07075

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ENPEP Proteins (ENPEP) by Origin

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Top referenced ENPEP Proteins

  1. Rat (Rattus) ENPEP Primary Antibody for - ABIN2009572 : Li, Wang, Cooper: cDNA cloning and expression of human glutamyl aminopeptidase (aminopeptidase A). in Genomics 1993 (PubMed)
    Show all 4 references for ABIN2009572

More Proteins for ENPEP Interaction Partners

Zebrafish Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP) interaction partners

  1. Study describes a zebrafish 2 kb glutamyl aminopeptidase (enpep) promoter fragment, and shows that it can drive gene expression specifically in the kidney during early and late development.

Mouse (Murine) Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP) interaction partners

  1. de-regulation of both PITX2 (show PITX2 Proteins) and ENPEP could contribute to an increased risk of atrial fibrillation in carriers of disease-associated variants.

  2. Demonstrate a novel role of APA in ANG-(1 (show ANGPT1 Proteins)-7) metabolism and suggest that the upregulation of APA, which occurs after myocardial infarction, may deprive the heart of cardioprotective ANG-(1 (show ANGPT1 Proteins)-7).

  3. Ischemia-induced angiogenesis is impaired in APA-KO mice partly through decreased HIF-1alpha (show HIF1A Proteins) stability by proteasomal degradation and subsequent suppression of HIF-1alpha (show HIF1A Proteins)-driven target protein expression such as growth factors.

  4. Replacement of active site residue glutamate (show GRIN1 Proteins)-215 of aminopeptidase A with aspartate or alanine leads to a strong decrease in the rate of hydrolysis of the synthetic substrate alpha-L-glutamyl-beta-naphthylamide.

  5. the C-terminal domain of aminopeptidase A acts as an intramolecular chaperone

  6. Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice.Elevated central concentrations of the vasopressor octapeptide angiotensin (Ang) II (show AGT Proteins) increase the water intake in mammals.

  7. Results demonstrate a key role of Thr (show TRH Proteins)-348 in substrate specificity of aminopeptidase A for N-terminal acidic amino acids by insuring the optimal positioning of the substrate during catalysis.

Human Glutamyl Aminopeptidase (Aminopeptidase A) (ENPEP) interaction partners

  1. The substrate Angiotensin II, the enzymes aminopeptidases-A, B, M as well as IRAP (show IL1RN Proteins) were detected in the jejunal mucosa.

  2. miR-125b acts as a tumor suppressor in breast tumorigenesis via its novel direct targets ENPEP, CK2-alpha, CCNJ, and MEGF9.

  3. These results explain the calcium-modulated substrate specificity of APA in central hypertension regulation

  4. There was no significant alteration in plasma APA activity in the patients with Chagas disease or dilated cardiomyopathies, as compared with that in health controls

  5. Rieger syndrome with microdeletions including only the PITX2 (show PITX2 Proteins) and ENPEP (glutamyl aminopeptidase) genes.

  6. Data show that APA appears to be an essential enzyme in the control of blood pressure via degradation of Angiotensin II.

  7. Data show that aminopeptidase A (APA) plays important roles in the regulation of blood pressure under both the physiological and pathological conditions.

  8. Data show that brain aminopeptidases act upon Ang I (show AGT Proteins), Ang II (show AGT Proteins) and Ang III (show AGT Proteins) in order to activate brain AT(1) receptors.

  9. rare and common variation in ENPEP may contribute to the development of renal and hypertensive disorders and warrants further study

  10. The presence of APA in several human brain nuclei sensitive to angiotensins and involved in blood pressure regulation suggests that APA in humans is an integral component of the brain renin (show REN Proteins) angiotensin system.

ENPEP Protein Profile

Protein Summary

ectoenzyme that selectively hydrolyzes acidic amino acid residues from the amino terminus of oligopeptides

Alternative names and synonyms associated with ENPEP

  • glutamyl aminopeptidase (aminopeptidase A) (ENPEP)
  • glutamyl aminopeptidase (enpep)
  • glutamyl aminopeptidase (ECU01_1470)
  • glutamyl aminopeptidase (pepA)
  • glutamyl aminopeptidase (AaeL_AAEL007201)
  • glutamyl aminopeptidase (CpipJ_CPIJ011103)
  • glutamyl aminopeptidase (Eint_011390)
  • glutamyl aminopeptidase (Halhy_0222)
  • glutamyl aminopeptidase (Enpep)
  • 6030431M22Rik protein
  • APA protein
  • Bp-1/6C3 protein
  • CD249 protein
  • gp160 protein
  • im:7152184 protein
  • Ly-51 protein
  • Ly51 protein
  • si:ch211-146m5.2 protein

Protein level used designations for ENPEP

glutamyl aminopeptidase (aminopeptidase A) , aminopeptidase A , glutamyl aminopeptidase , AP-A , BP-1/6C3 antigen , EAP , aminopeptidase-A , differentiation antigen gp160

GENE ID SPECIES
428771 Gallus gallus
461437 Pan troglodytes
478517 Canis lupus familiaris
504088 Danio rerio
860321 Encephalitozoon cuniculi GB-M1
932959 Streptococcus pneumoniae R6
5568916 Aedes aegypti
6043869 Culex quinquefasciatus
8798939 Streptococcus mitis B6
9698615 Encephalitozoon intestinalis ATCC 50506
10584375 Haliscomenobacter hydrossis DSM 1100
100168247 Acyrthosiphon pisum
100173346 Pongo abelii
13809 Mus musculus
64017 Rattus norvegicus
2028 Homo sapiens
397080 Sus scrofa
504350 Bos taurus
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