Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) (Internal Region) Peptide

Details for Product No. ABIN1382324
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Protein Name
Synonyms 9030414B18Rik, AI225830, C85377, Ire1a, Ire1alpha, Ire1p, Ern1, Ire1, Ire1b, IRE1, IRE1P, IRE1a, hIRE1p, RGD1559716
Protein Region
Internal Region
(1), (1), (6), (3), (1), (3)
Blocking Peptide (BP)
Pubmed 4 references available
Quantity 0.05 mg
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Availability Will be delivered in 2 to 3 Business Days
Characteristics 15 amino acids near the center of human IRE1p.
Alternative Name IRE1p
Application Notes IRE1p peptide is used for blocking the activity of IRE1p.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications McGettrick, ONeill: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, 2004 (PubMed).

Hawn, Verbon, Lettinga et al.: "A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1563-72, 2003 (PubMed).

Hayashi, Smith, Ozinsky et al.: "The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5." in: Nature, Vol. 410, Issue 6832, pp. 1099-103, 2001 (PubMed).

Miyoshi, Katayama, Imaizumi et al.: "Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line." in: Brain research. Molecular brain research, Vol. 85, Issue 1-2, pp. 68-76, 2001 (PubMed).

Catalog No. ABIN1382324
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