G-Protein Signaling Modulator 2 (GPSM2) (N-Term) Peptide
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- Target See all GPSM2 products
- GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SGNLGNTLKV LGNFDEAIVC CQRHLDISRE LNDKVGEARA LYNLGNVYHA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GPSM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
- Synonyms
- CMCS Peptide, DFNB82 Peptide, LGN Peptide, PINS Peptide, dfnb82 Peptide, lgn Peptide, pins Peptide, RGD1560967 Peptide, Pinsa Peptide, zgc:63574 Peptide, 6230410J09Rik Peptide, Pins Peptide, G protein signaling modulator 2 Peptide, G-protein signaling modulator 2 S homeolog Peptide, G-protein signaling modulator 2 Peptide, G-protein signalling modulator 2 (AGS3-like, C. elegans) Peptide, GPSM2 Peptide, gpsm2.S Peptide, Gpsm2 Peptide, gpsm2 Peptide
- Background
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The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).
Alias Symbols: CMCS, DFNB82, LGN, PINS
Protein Size: 684 - Molecular Weight
- 75 kDa
- Gene ID
- 29899
- NCBI Accession
- NM_013296, NP_037428
- UniProt
- P81274
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