Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2) (N-Term) Peptide
KCNA2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KCNA2 products
- KCNA2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VATGDPADEA AALPGHPQDT YDPEADHECC ERVVINISGL RFETQLKTLA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- KCNA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KCNA2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 2 (KCNA2))
- Synonyms
- KCNA2 Peptide, kcna2 Peptide, HBK5 Peptide, HK4 Peptide, HUKIV Peptide, KV1.2 Peptide, MK2 Peptide, NGK1 Peptide, RBK2 Peptide, Akr6a4 Peptide, ENSMUSG00000074335 Peptide, Gm10672 Peptide, Kca1-2 Peptide, Kv1.2 Peptide, Mk-2 Peptide, BK2 Peptide, XSha2 Peptide, k(v)1.2 Peptide, kcna2-a Peptide, kv1.2 Peptide, potassium voltage-gated channel subfamily A member 2 Peptide, potassium channel, voltage gated shaker related subfamily A, member 1 Peptide, potassium voltage-gated channel, shaker-related subfamily, member 2 Peptide, potassium channel, voltage gated shaker related subfamily A, member 2 S homeolog Peptide, KCNA2 Peptide, kcna1 Peptide, Kcna2 Peptide, LOC100537815 Peptide, kcna2.S Peptide
- Background
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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
Alias Symbols: HK4, MK2, HBK5, NGK1, RBK2, HUKIV, KV1.2, EIEE32
Protein Size: 499 - Gene ID
- 3737
- NCBI Accession
- NM_001204269, NP_001191198
- UniProt
- P16389
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