Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1) Peptide
ALG1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ALG1 products
- ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALG1 antibody (Catalog #: ARP49445_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ALG1 (Chitobiosyldiphosphodolichol beta-Mannosyltransferase (ALG1))
- Synonyms
- CDG1K Peptide, HMAT1 Peptide, HMT-1 Peptide, HMT1 Peptide, MT-1 Peptide, Mat-1 Peptide, hMat-1 Peptide, zgc:66221 Peptide, wu:fi34b12 Peptide, alg1 Peptide, hmat1 Peptide, hmt1 Peptide, ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase Peptide, asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase) Peptide, Beta-mannosyltransferase Peptide, ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase L homeolog Peptide, ALG1 Peptide, Alg1 Peptide, alg1 Peptide, alg1.L Peptide
- Background
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ALG1 catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. Defects in ALG1 are the cause of congenital disorder of glycosylation type 1K (CDG1K).The biosynthesis of lipid-linked oligosaccharides is highly conserved among eukaryotes and is catalyzed by 14 glycosyltransferases in an ordered stepwise manner. Mannosyltransferase I (MT I) catalyzes the first mannosylation step in this process.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-421 BM767933.1 1-421 422-1179 AY359073.1 416-1173 1180-1444 CA455103.1 259-523 1445-1939 CD366777.1 17-511 c 1940-2122 BC031095.1 1931-2113 2123-2149 BQ002699.1 1-27 c
Alias Symbols: HMAT1, HMT-1, HMT1, MT-1, CDG1K, Mat-1, hMat-1
Protein Size: 464 - Molecular Weight
- 52 kDa
- Gene ID
- 56052
- NCBI Accession
- NM_019109, NP_061982
- UniProt
- Q9BT22
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