Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2) Peptide
AOC2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AOC2 products
- AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AOC2 antibody (Catalog #: ARP45055_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))
- Synonyms
- DAO2 Peptide, RAO Peptide, AOC2 Peptide, AOC3 Peptide, aoc3 Peptide, wu:fa94a08 Peptide, wu:fe14c05 Peptide, zgc:113006 Peptide, amine oxidase, copper containing 2 Peptide, amine oxidase, copper containing 2 (retina-specific) Peptide, membrane primary amine oxidase-like Peptide, retina-specific copper amine oxidase Peptide, AOC2 Peptide, Aoc2 Peptide, LOC100353051 Peptide, aoc2 Peptide
- Background
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Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine.Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
Alias Symbols: DAO2, RAO
Protein Size: 756 - Molecular Weight
- 84 kDa
- Gene ID
- 314
- NCBI Accession
- NM_009590, NP_033720
- UniProt
- O75106
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