B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) (N-Term) Peptide
BCL11A
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all BCL11A products
- BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BCL11A antibody (Catalog #: ARP39322_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
- Synonyms
- 2810047E18Rik Peptide, BCL-11A Peptide, Ctip1 Peptide, D930021L15Rik Peptide, Evi9 Peptide, Evi9a Peptide, Evi9b Peptide, Evi9c Peptide, mKIAA1809 Peptide, BCL11A-L Peptide, BCL11A-S Peptide, BCL11A-XL Peptide, BCL11a-M Peptide, CTIP1 Peptide, EVI9 Peptide, HBFQTL5 Peptide, ZNF856 Peptide, bcl11a Peptide, wu:fi09f10 Peptide, zgc:136898 Peptide, B cell CLL/lymphoma 11A (zinc finger protein) Peptide, B-cell CLL/lymphoma 11A Peptide, B-cell CLL/lymphoma 11A L homeolog Peptide, B-cell CLL/lymphoma 11Aa Peptide, Bcl11a Peptide, BCL11A Peptide, bcl11a.L Peptide, bcl11aa Peptide
- Background
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BCL11A Is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, ZNF856
Protein Interaction Partner: NR2F1,NR2F2,NR2F1
Protein Size: 835 - Molecular Weight
- 91 kDa
- Gene ID
- 53335
- NCBI Accession
- NM_022893, NP_075044
- UniProt
- Q9H165
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