Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3) (N-Term) Peptide
CAPZA3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CAPZA3 products
- CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CAPZA3 antibody (Catalog #: ARP58604_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))
- Synonyms
- CAPZA3 Peptide, CAPPA3 Peptide, Gsg3 Peptide, 510-4 Peptide, Cappa3 Peptide, Tex8 Peptide, repro32 Peptide, capping actin protein of muscle Z-line alpha subunit 3 Peptide, capping protein (actin filament) muscle Z-line, alpha 3 Peptide, CAPZA3 Peptide, Capza3 Peptide
- Background
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F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA3 may play a role in the morphogenesis of spermatid.This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.
Alias Symbols: CAPPA3, Gsg3
Protein Interaction Partner: ACTG1,CAPZA2
Protein Size: 299 - Molecular Weight
- 33 kDa
- Gene ID
- 93661
- NCBI Accession
- NM_033328, NP_201585
- UniProt
- Q96KX2
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