Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2) Peptide
CPSF2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CPSF2 products
- CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CPSF2 antibody (Catalog #: ARP40857_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CPSF2 (Cleavage and Polyadenylation Specific Factor 2, 100kDa (CPSF2))
- Synonyms
- CPSF100 Peptide, 100kDa Peptide, 2610024B04Rik Peptide, AI662483 Peptide, Cpsf Peptide, MCPSF Peptide, mKIAA1367 Peptide, zgc:92484 Peptide, cpsf2-A Peptide, cleavage and polyadenylation specific factor 2 Peptide, cleavage and polyadenylation specific factor 2 S homeolog Peptide, cleavage and polyadenylation specificity factor subunit 2 Peptide, CPSF2 Peptide, Cpsf2 Peptide, cpsf2 Peptide, PAAG_07931 Peptide, cpsf2.S Peptide, LOC582050 Peptide, LOC100157277 Peptide, LOC100179344 Peptide
- Background
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CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.
Alias Symbols: CPSF100, KIAA1367
Protein Interaction Partner: POLR2A,CSTF2,RNPS1
Protein Size: 782 - Molecular Weight
- 88 kDa
- Gene ID
- 53981
- NCBI Accession
- NM_017437, NP_059133
- UniProt
- Q9P2I0
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