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Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) Peptide

DVL2 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN976047
  • Target See all DVL2 products
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DVL2 antibody (Catalog #: ARP32102_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    Synonyms
    Xdsh Peptide, dishevelled Peptide, dsh Peptide, dvl Peptide, Dvl-2 Peptide, xdsh Peptide, wu:fc05d12 Peptide, wu:fo71e09 Peptide, wu:fp54a02 Peptide, zgc:55372 Peptide, dishevelled segment polarity protein 2 Peptide, dishevelled segment polarity protein 2 L homeolog Peptide, DVL2 Peptide, dvl2 Peptide, Dvl2 Peptide, dvl2.L Peptide
    Background
    DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: -

    Protein Interaction Partner: A2BP1,AP1M1,AP2M1,ARR3,ARRB1,ARRB2,ATN1,AXIN1,BAG3,BAHD1,C16orf48,C9orf100,CCDC33,CPSF7,CSNK1E,DAAM1,DDI1,DPPA2,DVL2,DYNLT1,FAM105B,FZD4,MCRS1,PCBD1,POLI,PPM1A,PRKCA,PRKCB,PRKCG,PRPF3,RAC1,RBPMS,RHOA,RHOXF2,RNPS1,RUNX2,SNF8,SNIP1,SORBS3,TCEB3B,THAP1,TIFA,TP53,TRAF2,U2AF2,USP5,VANGL1,ZBTB8B,ZNF165,ZNF250,ZNF263,AP1M1,AP2M1,ARR3,ARRB1,AXIN1,BAG3,BAHD1,C16orf48,C9orf100,CCDC33,CPSF7,CSNK1E,CSNK2A1,CTNNB1,DAB2,DDI1,DPPA2,DVL2,FAM105B,MAP3K1,MCRS1,PCBD1,POLI,PRPF3,RBPMS,RHOXF2,RNPS1,SNF8,SNIP1,SORBS3,TCEB3B,THAP1,TIFA,TP53,TRAF2,U2AF2,USP5,ZBTB8A,ZNF165,ZNF250,ZNF263

    Protein Size: 736
    Molecular Weight
    79 kDa
    Gene ID
    1856
    NCBI Accession
    NM_004422, NP_004413
    UniProt
    O14641
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