Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1) Peptide
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- Target See all ECH1 products
- ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ECH1 antibody (Catalog #: ARP43560_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ECH1 (Enoyl Coenzyme A Hydratase 1, Peroxisomal (ECH1))
- Synonyms
- HPXEL Peptide, Pxel Peptide, AA617331 Peptide, enoyl-CoA hydratase 1, peroxisomal Peptide, enoyl CoA hydratase 1, peroxisomal Peptide, enoyl-CoA hydratase 1 Peptide, delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Peptide, enoyl-CoA hydratase 1, peroxisomal L homeolog Peptide, enoyl coenzyme A hydratase 1, peroxisomal Peptide, ech1 Peptide, ECH1 Peptide, LOC747511 Peptide, ech1.L Peptide, Ech1 Peptide
- Background
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ECH1 is a member of the hydratase/isomerase superfamily. ECH1 shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The protein contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway.This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Alias Symbols: HPXEL
Protein Interaction Partner: CSTF2,EEF1G,PAFAH1B3,SERPINB9,TIMP1,TLR10,CSTF2,EEF1G,PAFAH1B3,SERPINB9,TIMP1
Protein Size: 328 - Molecular Weight
- 36 kDa
- Gene ID
- 1891
- NCBI Accession
- NM_001398, NP_001389
- UniProt
- Q13011
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