F-Box and WD Repeat Domain Containing 11 (FBXW11) Peptide
FBXW11
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FBXW11 products
- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBXW11 antibody (Catalog #: ARP43379_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
- Synonyms
- BTRC2 Peptide, BTRCP2 Peptide, FBW1B Peptide, FBXW1B Peptide, Fbw11 Peptide, Hos Peptide, 2310065A07Rik Peptide, AA536858 Peptide, Fbxw1b Peptide, HOS Peptide, btrc2 Peptide, fbxw11a Peptide, wu:fa12e12 Peptide, wu:fb11f03 Peptide, zgc:63728 Peptide, fbxw11 Peptide, fbxw11b Peptide, fbxw1b Peptide, wu:fd14d12 Peptide, wu:fi43f07 Peptide, F-box and WD repeat domain containing 11 Peptide, F-box and WD-40 domain protein 11 Peptide, F-box/WD repeat-containing protein 11 Peptide, F-box and WD repeat domain containing 11b Peptide, F-box and WD repeat domain containing 11a Peptide, FBXW11 Peptide, Fbxw11 Peptide, LOC100199403 Peptide, fbxw11b Peptide, fbxw11a Peptide
- Background
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FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Alias Symbols: BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
Protein Interaction Partner: BTRC,CDC25A,CUL1,FBXW11,GLI2,IFNAR1,NFKB1,NFKBIA,WEE1,ARIH1,ATG4B,BTRC,CDC25B,CLPX,CLSPN,CUL1,FAM123B,FBXW11,HIVEP1,HIVEP2,KHDRBS2,MYO10,NFKBIA,NRD1,NUDC,OGT,PDCD4,RPRM,SKP1,SUN2,TFAP4,TUBGCP3,USP37,USP47,WEE1,ZRANB1
Protein Size: 529 - Molecular Weight
- 61 kDa
- Gene ID
- 23291
- NCBI Accession
- NM_033644, NP_387448
- UniProt
- Q9UKB1
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