F-Box and WD Repeat Domain Containing 8 (FBXW8) (Middle Region) Peptide
FBXW8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FBXW8 products
- FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FBXW8 Antibody(ARP55586_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
- Synonyms
- FBW6 Peptide, FBW8 Peptide, FBX29 Peptide, FBXO29 Peptide, FBXW6 Peptide, 4930438M06Rik Peptide, Fbx29 Peptide, F-box and WD repeat domain containing 8 Peptide, ring finger protein, transmembrane 2 Peptide, F-box and WD-40 domain protein 8 Peptide, FBXW8 Peptide, Fbxw8 Peptide, RNFT2 Peptide
- Background
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FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.
Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6
Protein Interaction Partner: SKP1,CUL7,RBX1,SKP1,CUL7,EP300,RBX1,SKP1
Protein Size: 598 - Molecular Weight
- 67 kDa
- Gene ID
- 26259
- NCBI Accession
- NM_153348, NP_699179
- UniProt
- Q8N3Y1
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